Fusion Partner Toolchest for the Stabilization and Crystallization of G Protein-Coupled Receptors
Tóm tắt
Từ khóa
Tài liệu tham khảo
Alexandrov, 2008, Microscale fluorescent thermal stability assay for membrane proteins, Structure, 16, 351, 10.1016/j.str.2008.02.004
Bjarnadóttir, 2006, Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse, Genomics, 88, 263, 10.1016/j.ygeno.2006.04.001
Caffrey, 2009, Crystallizing membrane proteins using lipidic mesophases, Nat. Protoc., 4, 706, 10.1038/nprot.2009.31
Chae, 2010, Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins, Nat. Methods, 7, 1003, 10.1038/nmeth.1526
Cherezov, 2004, A robotic system for crystallizing membrane and soluble proteins in lipidic mesophases, Acta Crystallogr. D Biol. Crystallogr., 60, 1795, 10.1107/S0907444904019109
Cherezov, 2007, High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor, Science, 318, 1258, 10.1126/science.1150577
Chien, 2010, Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist, Science, 330, 1091, 10.1126/science.1197410
Day, 2007, A monoclonal antibody for G protein-coupled receptor crystallography, Nat. Methods, 4, 927
Doré, 2011, Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine, Structure, 19, 1283, 10.1016/j.str.2011.06.014
Engel, 2002, Insertion of carrier proteins into hydrophilic loops of the Escherichia coli lactose permease, Biochim. Biophys. Acta, 1564, 38, 10.1016/S0005-2736(02)00398-X
Feng, 2004, Detection and structure determination of an equilibrium unfolding intermediate of Rd-apocytochrome b562: native fold with non-native hydrophobic interactions, J. Mol. Biol., 343, 1477, 10.1016/j.jmb.2004.08.099
Granier, 2012, Structure of the δ-opioid receptor bound to naltrindole, Nature, 485, 400, 10.1038/nature11111
Haga, 2012, Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist, Nature, 482, 547, 10.1038/nature10753
Hanson, 2008, A specific cholesterol binding site is established by the 2.8 A structure of the human beta(2)-adrenergic receptor, Structure, 16, 897, 10.1016/j.str.2008.05.001
Hanson, 2012, Crystal structure of a lipid G protein-coupled receptor, Science, 335, 851, 10.1126/science.1215904
Hino, 2012, G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody, Nature, 482, 237, 10.1038/nature10750
Jaakola, 2008, The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist, Science, 322, 1211, 10.1126/science.1164772
Kimura, 2009, Folding energy landscape of cytochrome cb562, Proc. Natl. Acad. Sci. USA, 106, 7834, 10.1073/pnas.0902562106
Kruse, 2012, Structure and dynamics of the M3 muscarinic acetylcholine receptor, Nature, 482, 552, 10.1038/nature10867
Lebon, 2011, Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation, Nature, 474, 521, 10.1038/nature10136
Lederer, 1981, Improvement of the 2.5 A resolution model of cytochrome b562 by redetermining the primary structure and using molecular graphics, J. Mol. Biol., 148, 427, 10.1016/0022-2836(81)90185-6
Liu, 2012, Structural basis for allosteric regulation of GPCRs by sodium ions, Science, 10.1126/science.1219218
Manglik, 2012, Crystal structure of the μ-opioid receptor bound to a morphinan antagonist, Nature, 485, 321, 10.1038/nature10954
Miller, 2011, Engineering an ultra-thermostable β(1)-adrenoceptor, J. Mol. Biol., 413, 628, 10.1016/j.jmb.2011.08.057
Palczewski, 2000, Crystal structure of rhodopsin: A G protein-coupled receptor, Science, 289, 739, 10.1126/science.289.5480.739
Privé, 1994, Fusion proteins as tools for crystallization: the lactose permease from Escherichia coli, Acta Crystallogr. D Biol. Crystallogr., 50, 375, 10.1107/S0907444993014301
Rasmussen, 2007, Crystal structure of the human beta2 adrenergic G-protein-coupled receptor, Nature, 450, 383, 10.1038/nature06325
Rasmussen, 2011, Structure of a nanobody-stabilized active state of the β(2) adrenoceptor, Nature, 469, 175, 10.1038/nature09648
Rasmussen, 2011, Crystal structure of the β2 adrenergic receptor-Gs protein complex, Nature, 477, 549, 10.1038/nature10361
Rosenbaum, 2007, GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function, Science, 318, 1266, 10.1126/science.1150609
Serrano-Vega, 2008, Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form, Proc. Natl. Acad. Sci. USA, 105, 877, 10.1073/pnas.0711253105
Shimamura, 2011, Structure of the human histamine H1 receptor complex with doxepin, Nature, 475, 65, 10.1038/nature10236
Thompson, 2012, Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic, Nature, 485, 395, 10.1038/nature11085
Wacker, 2010, Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography, J. Am. Chem. Soc., 132, 11443, 10.1021/ja105108q
Warne, 2008, Structure of a beta1-adrenergic G-protein-coupled receptor, Nature, 454, 486, 10.1038/nature07101
West, 2011, Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX, Structure, 19, 1424, 10.1016/j.str.2011.08.001
Wu, 2010, Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists, Science, 330, 1066, 10.1126/science.1194396
Wu, 2012, Structure of the human κ-opioid receptor in complex with JDTic, Nature, 485, 327, 10.1038/nature10939
Xu, 2011, Development of an automated high throughput LCP-FRAP assay to guide membrane protein crystallization in lipid mesophases, Cryst. Growth Des., 11, 1193, 10.1021/cg101385e