Function and cancer genomics of FAT family genes

International Journal of Oncology - Tập 41 Số 6 - Trang 1913-1918 - 2012
Masaru Katoh1
1Division of Integrative Omics and Bioinformatics, National Cancer Center, Tokyo 104-0045, Japan.

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Bryant, 1988, Mutations at the fat locus interfere with cell proliferation control and epithelial morphogenesis in Drosophila, Dev Biol, 129, 541, 10.1016/0012-1606(88)90399-5

Woods, 1991, The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions, Cell, 66, 451, 10.1016/0092-8674(81)90009-X

Strand, 1994, The Drosophila lethal(2) giant larvae tumor suppressor protein is a component of the cytoskeleton, J Cell Biol, 127, 1345, 10.1083/jcb.127.5.1345

Justice, 1995, The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation, Genes Dev, 9, 534, 10.1101/gad.9.5.534

Bilder, 2000, Localization of apical epithelial determinants by the basolateral PDZ protein Scribble, Nature, 403, 676, 10.1038/35001108

Tapon, 2002, salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines, Cell, 110, 467, 10.1016/S0092-8674(02)00824-3

Pantalacci, 2003, The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila, Nat Cell Biol, 5, 921, 10.1038/ncb1051

Bryant, 1993, Tumor suppressor genes encoding proteins required for cell interactions and signal transduction in Drosophila, Dev Suppl, 239

Hariharan, 2006, Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila, Annu Rev Genet, 40, 335, 10.1146/annurev.genet.39.073003.100738

Saucedo, 2007, Filling out the Hippo pathway, Nat Rev Mol Cell Biol, 8, 613, 10.1038/nrm2221

Reddy, 2008, The Fat and Warts signaling pathways: new insights into their regulation, mechanism and conservation, Development, 135, 2827, 10.1242/dev.020974

Pan, 2010, The hippo signaling pathway in development and cancer, Dev Cell, 19, 491, 10.1016/j.devcel.2010.09.011

Genevet, 2011, The Hippo pathway and apico-basal cell polarity, Biochem J, 436, 213, 10.1042/BJ20110217

Yang, 2002, Regulation of Frizzled by fat-like cadherins during planar polarity signaling in the Drosophila compound eye, Cell, 108, 675, 10.1016/S0092-8674(02)00658-X

Strutt, 2002, Nonautonomous planar polarity patterning in Drosophila: dishevelled-independent functions of frizzled, Dev Cell, 3, 851, 10.1016/S1534-5807(02)00363-5

Axelrod, 2009, Progress and challenges in understanding planar cell polarity signaling, Semin Cell Dev Biol, 20, 964, 10.1016/j.semcdb.2009.08.001

Djiane, 2010, The Drosophila GIPC homologue can modulate myosin based processes and planar cell polarity but is not essential for development, PLoS One, 5, e11228, 10.1371/journal.pone.0011228

Axelrod, 1998, Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways, Genes Dev, 12, 2610, 10.1101/gad.12.16.2610

Mlodzik, 2002, Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation?, Trends Genet, 18, 564, 10.1016/S0168-9525(02)02770-1

Katoh, 2005, WNT/PCP signaling pathway and human cancer (Review), Oncol Rep, 14, 1583

Ishikawa, 2008, Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains, Science, 321, 401, 10.1126/science.1158159

Sopko, 2009, The skinny on Fat: an enormous cadherin that regulates cell adhesion, tissue growth, and planar cell polarity, Curr Opin Cell Biol, 21, 717, 10.1016/j.ceb.2009.07.001

Thomas, 2012, The roles of the cadherins Fat and Dachsous in planar polarity specification in Drosophila, Dev Dyn, 241, 27, 10.1002/dvdy.22736

Bosveld, 2012, Mechanical control of morphogenesis by Fat/Dachsous/Four-jointed planar cell polarity pathway, Science, 336, 724, 10.1126/science.1221071

Mahoney, 1991, The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily, Cell, 67, 853, 10.1016/0092-8674(91)90359-7

Tanoue, 2005, New insights into Fat cadherins, J Cell Sci, 118, 2347, 10.1242/jcs.02398

Hulpiau, 2009, Molecular evolution of the cadherin superfamily, Int J Biochem Cell Biol, 41, 349, 10.1016/j.biocel.2008.09.027

Dunne, 1995, Molecular cloning and tissue expression of FAT, the human homologue of the Drosophila fat gene that is located on chromosome 4q34-q35 and encodes a putative adhesion molecule, Genomics, 30, 207, 10.1006/geno.1995.9884

Wu, 2000, Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes, Proc Natl Acad Sci USA, 97, 3124, 10.1073/pnas.97.7.3124

Höng, 2004, Identification of new human cadherin genes using a combination of protein motif search and gene finding methods, J Mol Biol, 337, 307, 10.1016/j.jmb.2004.01.026

Katoh, 2006, Comparative integromics on FAT1, FAT2, FAT3 and FAT4, Int J Mol Med, 18, 523

Sadeqzadeh, 2011, Dual processing of FAT1 cadherin protein by human melanoma cells generates distinct protein products, J Biol Chem, 286, 28181, 10.1074/jbc.M111.234419

Magg, 2005, Processing of the human protocadherin Fat1 and translocation of its cytoplasmic domain to the nucleus, Exp Cell Res, 307, 100, 10.1016/j.yexcr.2005.03.006

Tanoue, 2004, Mammalian Fat1 cadherin regulates actin dynamics and cell-cell contact, J Cell Biol, 165, 517, 10.1083/jcb.200403006

Moeller, 2004, Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization, EMBO J, 23, 3769, 10.1038/sj.emboj.7600380

Schreiner, 2006, The intracellular domain of the human protocadherin hFat1 interacts with Homer signalling scaffolding proteins, FEBS Lett, 580, 5295, 10.1016/j.febslet.2006.08.079

Skouloudaki, 2009, Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development, Proc Natl Acad Sci USA, 106, 8579, 10.1073/pnas.0811691106

Hou, 2006, The Fat1 cadherin integrates vascular smooth muscle cell growth and migration signals, J Cell Biol, 173, 417, 10.1083/jcb.200508121

Ishiuchi, 2009, Mammalian Fat and Dachsous cadherins regulate apical membrane organization in the embryonic cerebral cortex, J Cell Biol, 185, 959, 10.1083/jcb.200811030

Katoh, 2004, Identification and characterization of human MPP7 gene and mouse Mpp7 gene in silico, Int J Mol Med, 13, 333

Saburi, 2008, Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease, Nat Genet, 40, 1010, 10.1038/ng.179

Jones, 2007, Planar cell polarity signaling in vertebrates, Bioessays, 29, 120, 10.1002/bies.20526

Kibar, 2001, Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail, Nat Genet, 28, 251, 10.1038/90081

van Hateren, 2011, FatJ acts via the Hippo mediator Yap1 to restrict the size of neural progenitor cell pools, Development, 138, 1893, 10.1242/dev.064204

Nakaya, 2007, Identification of homozygous deletions of tumor suppressor gene FAT in oral cancer using CGH-array, Oncogene, 26, 5300, 10.1038/sj.onc.1210330

Chosdol, 2009, Frequent loss of heterozygosity and altered expression of the candidate tumor suppressor gene ‘FAT’ in human astrocytic tumors, BMC Cancer, 9, 5, 10.1186/1471-2407-9-5

Lee, 2012, Differentially expressed genes regulating the progression of ductal carcinoma in situ to invasive breast cancer, Cancer Res, 72, 4574, 10.1158/0008-5472.CAN-12-0636

de Bock, 2012, The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemia, Leukemia, 26, 918, 10.1038/leu.2011.319

Settakorn, 2005, FAT, E-cadherin, β-catenin, HER 2/neu, Ki67 immuno-expression, and histological grade in intrahepatic cholangiocarcinoma, J Clin Pathol, 58, 1249, 10.1136/jcp.2005.026575

Rohrbeck, 2009, Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1, PLoS One, 4, e7315, 10.1371/journal.pone.0007315

Qi, 2009, Identification of Fat4 as a candidate tumor suppressor gene in breast cancers, Int J Cancer, 124, 793, 10.1002/ijc.23775

Rauch, 2012, DNA methylation biomarkers for lung cancer, Tumour Biol, 33, 287, 10.1007/s13277-011-0282-2

Jones, 2008, Core signaling pathways in human pancreatic cancers revealed by global genomic analyses, Science, 321, 1801, 10.1126/science.1164368

Agrawal, 2011, Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1, Science, 333, 1154, 10.1126/science.1206923

Li, 2011, Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma, Nat Genet, 43, 828, 10.1038/ng.903

Nikolaev, 2011, Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma, Nat Genet, 44, 133, 10.1038/ng.1026

Zang, 2012, Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes, Nat Genet, 44, 570, 10.1038/ng.2246

Imajo, 2012, A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling, EMBO J, 31, 1109, 10.1038/emboj.2011.487

Katoh, 2007, WNT signaling pathway and stem cell signaling network, Clin Cancer Res, 13, 4042, 10.1158/1078-0432.CCR-06-2316

Yu, 2012, Regulation of the Hippo-YAP pathway by G-Protein-coupled receptor signaling, Cell, 150, 780, 10.1016/j.cell.2012.06.037

Huang, 2012, The N-terminal phosphodegron targets TAZ/WWTR1 protein for SCF β-TrCP-dependent degradation in response to phosphatidylinositol 3-kinase inhibition, J Biol Chem, 287, 26245, 10.1074/jbc.M112.382036

Cordenonsi, 2011, The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells, Cell, 147, 759, 10.1016/j.cell.2011.09.048