Function and cancer genomics of FAT family genes
Tóm tắt
Từ khóa
Tài liệu tham khảo
Bryant, 1988, Mutations at the fat locus interfere with cell proliferation control and epithelial morphogenesis in Drosophila, Dev Biol, 129, 541, 10.1016/0012-1606(88)90399-5
Woods, 1991, The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions, Cell, 66, 451, 10.1016/0092-8674(81)90009-X
Strand, 1994, The Drosophila lethal(2) giant larvae tumor suppressor protein is a component of the cytoskeleton, J Cell Biol, 127, 1345, 10.1083/jcb.127.5.1345
Justice, 1995, The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation, Genes Dev, 9, 534, 10.1101/gad.9.5.534
Bilder, 2000, Localization of apical epithelial determinants by the basolateral PDZ protein Scribble, Nature, 403, 676, 10.1038/35001108
Tapon, 2002, salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines, Cell, 110, 467, 10.1016/S0092-8674(02)00824-3
Pantalacci, 2003, The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila, Nat Cell Biol, 5, 921, 10.1038/ncb1051
Bryant, 1993, Tumor suppressor genes encoding proteins required for cell interactions and signal transduction in Drosophila, Dev Suppl, 239
Hariharan, 2006, Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila, Annu Rev Genet, 40, 335, 10.1146/annurev.genet.39.073003.100738
Reddy, 2008, The Fat and Warts signaling pathways: new insights into their regulation, mechanism and conservation, Development, 135, 2827, 10.1242/dev.020974
Pan, 2010, The hippo signaling pathway in development and cancer, Dev Cell, 19, 491, 10.1016/j.devcel.2010.09.011
Genevet, 2011, The Hippo pathway and apico-basal cell polarity, Biochem J, 436, 213, 10.1042/BJ20110217
Yang, 2002, Regulation of Frizzled by fat-like cadherins during planar polarity signaling in the Drosophila compound eye, Cell, 108, 675, 10.1016/S0092-8674(02)00658-X
Strutt, 2002, Nonautonomous planar polarity patterning in Drosophila: dishevelled-independent functions of frizzled, Dev Cell, 3, 851, 10.1016/S1534-5807(02)00363-5
Axelrod, 2009, Progress and challenges in understanding planar cell polarity signaling, Semin Cell Dev Biol, 20, 964, 10.1016/j.semcdb.2009.08.001
Djiane, 2010, The Drosophila GIPC homologue can modulate myosin based processes and planar cell polarity but is not essential for development, PLoS One, 5, e11228, 10.1371/journal.pone.0011228
Axelrod, 1998, Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways, Genes Dev, 12, 2610, 10.1101/gad.12.16.2610
Mlodzik, 2002, Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation?, Trends Genet, 18, 564, 10.1016/S0168-9525(02)02770-1
Katoh, 2005, WNT/PCP signaling pathway and human cancer (Review), Oncol Rep, 14, 1583
Ishikawa, 2008, Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains, Science, 321, 401, 10.1126/science.1158159
Sopko, 2009, The skinny on Fat: an enormous cadherin that regulates cell adhesion, tissue growth, and planar cell polarity, Curr Opin Cell Biol, 21, 717, 10.1016/j.ceb.2009.07.001
Thomas, 2012, The roles of the cadherins Fat and Dachsous in planar polarity specification in Drosophila, Dev Dyn, 241, 27, 10.1002/dvdy.22736
Bosveld, 2012, Mechanical control of morphogenesis by Fat/Dachsous/Four-jointed planar cell polarity pathway, Science, 336, 724, 10.1126/science.1221071
Mahoney, 1991, The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily, Cell, 67, 853, 10.1016/0092-8674(91)90359-7
Hulpiau, 2009, Molecular evolution of the cadherin superfamily, Int J Biochem Cell Biol, 41, 349, 10.1016/j.biocel.2008.09.027
Dunne, 1995, Molecular cloning and tissue expression of FAT, the human homologue of the Drosophila fat gene that is located on chromosome 4q34-q35 and encodes a putative adhesion molecule, Genomics, 30, 207, 10.1006/geno.1995.9884
Wu, 2000, Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes, Proc Natl Acad Sci USA, 97, 3124, 10.1073/pnas.97.7.3124
Höng, 2004, Identification of new human cadherin genes using a combination of protein motif search and gene finding methods, J Mol Biol, 337, 307, 10.1016/j.jmb.2004.01.026
Katoh, 2006, Comparative integromics on FAT1, FAT2, FAT3 and FAT4, Int J Mol Med, 18, 523
Sadeqzadeh, 2011, Dual processing of FAT1 cadherin protein by human melanoma cells generates distinct protein products, J Biol Chem, 286, 28181, 10.1074/jbc.M111.234419
Magg, 2005, Processing of the human protocadherin Fat1 and translocation of its cytoplasmic domain to the nucleus, Exp Cell Res, 307, 100, 10.1016/j.yexcr.2005.03.006
Tanoue, 2004, Mammalian Fat1 cadherin regulates actin dynamics and cell-cell contact, J Cell Biol, 165, 517, 10.1083/jcb.200403006
Moeller, 2004, Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization, EMBO J, 23, 3769, 10.1038/sj.emboj.7600380
Schreiner, 2006, The intracellular domain of the human protocadherin hFat1 interacts with Homer signalling scaffolding proteins, FEBS Lett, 580, 5295, 10.1016/j.febslet.2006.08.079
Skouloudaki, 2009, Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development, Proc Natl Acad Sci USA, 106, 8579, 10.1073/pnas.0811691106
Hou, 2006, The Fat1 cadherin integrates vascular smooth muscle cell growth and migration signals, J Cell Biol, 173, 417, 10.1083/jcb.200508121
Ishiuchi, 2009, Mammalian Fat and Dachsous cadherins regulate apical membrane organization in the embryonic cerebral cortex, J Cell Biol, 185, 959, 10.1083/jcb.200811030
Katoh, 2004, Identification and characterization of human MPP7 gene and mouse Mpp7 gene in silico, Int J Mol Med, 13, 333
Saburi, 2008, Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease, Nat Genet, 40, 1010, 10.1038/ng.179
Kibar, 2001, Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail, Nat Genet, 28, 251, 10.1038/90081
van Hateren, 2011, FatJ acts via the Hippo mediator Yap1 to restrict the size of neural progenitor cell pools, Development, 138, 1893, 10.1242/dev.064204
Nakaya, 2007, Identification of homozygous deletions of tumor suppressor gene FAT in oral cancer using CGH-array, Oncogene, 26, 5300, 10.1038/sj.onc.1210330
Chosdol, 2009, Frequent loss of heterozygosity and altered expression of the candidate tumor suppressor gene ‘FAT’ in human astrocytic tumors, BMC Cancer, 9, 5, 10.1186/1471-2407-9-5
Lee, 2012, Differentially expressed genes regulating the progression of ductal carcinoma in situ to invasive breast cancer, Cancer Res, 72, 4574, 10.1158/0008-5472.CAN-12-0636
de Bock, 2012, The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemia, Leukemia, 26, 918, 10.1038/leu.2011.319
Settakorn, 2005, FAT, E-cadherin, β-catenin, HER 2/neu, Ki67 immuno-expression, and histological grade in intrahepatic cholangiocarcinoma, J Clin Pathol, 58, 1249, 10.1136/jcp.2005.026575
Rohrbeck, 2009, Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1, PLoS One, 4, e7315, 10.1371/journal.pone.0007315
Qi, 2009, Identification of Fat4 as a candidate tumor suppressor gene in breast cancers, Int J Cancer, 124, 793, 10.1002/ijc.23775
Rauch, 2012, DNA methylation biomarkers for lung cancer, Tumour Biol, 33, 287, 10.1007/s13277-011-0282-2
Jones, 2008, Core signaling pathways in human pancreatic cancers revealed by global genomic analyses, Science, 321, 1801, 10.1126/science.1164368
Agrawal, 2011, Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1, Science, 333, 1154, 10.1126/science.1206923
Li, 2011, Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma, Nat Genet, 43, 828, 10.1038/ng.903
Nikolaev, 2011, Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma, Nat Genet, 44, 133, 10.1038/ng.1026
Zang, 2012, Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes, Nat Genet, 44, 570, 10.1038/ng.2246
Imajo, 2012, A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling, EMBO J, 31, 1109, 10.1038/emboj.2011.487
Katoh, 2007, WNT signaling pathway and stem cell signaling network, Clin Cancer Res, 13, 4042, 10.1158/1078-0432.CCR-06-2316
Yu, 2012, Regulation of the Hippo-YAP pathway by G-Protein-coupled receptor signaling, Cell, 150, 780, 10.1016/j.cell.2012.06.037
Huang, 2012, The N-terminal phosphodegron targets TAZ/WWTR1 protein for SCF β-TrCP-dependent degradation in response to phosphatidylinositol 3-kinase inhibition, J Biol Chem, 287, 26245, 10.1074/jbc.M112.382036