Frontal solubilisation chromatography

The behaviour of three non-electrolytes has been studied in both frontal and elution chromatography with an ion-exchange resin as stationary phase and an aqueous solution of ethanol as the mobile phase. On the basis of the plate-equilibrium theory, an equation is derived for the breakthrough graph in frontal chromatography. This is simply the integral of the equation for the graph in elution chromatography. Good agreement is found between the experimental breakthrough results and the equation, as well as between the distribution ratios and plate numbers as evaluated by the two Chromatographie methods.