From traditional medicine to modern oncology: Scutellarin, a promising natural compound in cancer treatment
Tài liệu tham khảo
Abéngozar, 2012, Blocking ephrinB2 with highly specific antibodies inhibits angiogenesis, lymphangiogenesis, and tumor growth, Blood, 119, 4565, 10.1182/blood-2011-09-380006
Avendaño, 2015, Chapter 1 - general aspects of cancer chemotherapy, 1
Bao, 2020, Scutellarin exerts anticancer effects on human leukemia cells via induction of Sub-G1 cell cycle arrest, apoptosis and also inhibits migration and invasion by targeting Raf/MEK/ERK signalling pathway, J. Buon, 25, 1050
Bayat Mokhtari, 2017, Combination therapy in combating cancer, Oncotarget, 8, 38022, 10.18632/oncotarget.16723
Bonavida, 2015, Nitric oxide-mediated sensitization of resistant tumor cells to apoptosis by chemo-immunotherapeutics, Redox Biol., 6, 486, 10.1016/j.redox.2015.08.013
Brabletz, 2018, EMT in cancer, Nat. Rev. Cancer, 18, 128, 10.1038/nrc.2017.118
Cao, 2019, Scutellarin suppresses proliferation and promotes apoptosis in A549 lung adenocarcinoma cells via AKT/mTOR/4EBP1 and STAT3 pathways, Thorac. Cancer, 10, 492, 10.1111/1759-7714.12962
Cerecetto, 2005, Pharmacological properties of indazole derivatives: recent developments, Mini Rev. Med. Chem., 5, 869, 10.2174/138955705774329564
Chan, 2009, Scutellarin sensitizes drug-evoked colon cancer cell apoptosis through enhanced caspase-6 activation, Anticancer Res., 29, 3043
Chen, 2023, Effects of breviscapine on cerebral ischemia-reperfusion injury and intestinal flora imbalance by regulating the TLR4/MyD88/NF-κB signaling pathway in rats, J. Ethnopharmacol., 300, 10.1016/j.jep.2022.115691
Chen, 2018, Integrated transcript and metabolite profiles reveal that EbCHI plays an important role in scutellarin accumulation in Erigeron breviscapus hairy roots, Front. Plant Sci., 9
Chen, 2022, Scutellarin enhances anti-tumor immune responses by reducing TNFR2-expressing CD4+Foxp3+ regulatory T cells, Biomed. Pharmacother., 151, 10.1016/j.biopha.2022.113187
Chen, 2013, TNFR2 is critical for the stabilization of the CD4+Foxp3+ regulatory T cell phenotype in the inflammatory environment, J. Immunol., 190, 1076, 10.4049/jimmunol.1202659
Collaboration, 2022, Cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life years for 29 cancer groups from 2010 to 2019: a systematic analysis for the global burden of disease study 2019, JAMA Oncol., 8, 420, 10.1001/jamaoncol.2021.6987
Cowles, 2000, Integrin-mediated signaling regulates AP-1 transcription factors and proliferation in osteoblasts, J. Biomed. Mater. Res., 52, 725, 10.1002/1097-4636(20001215)52:4<725::AID-JBM18>3.0.CO;2-O
Crona, 2017, A systematic review of strategies to prevent cisplatin‐induced nephrotoxicity, Oncol., 22, 609, 10.1634/theoncologist.2016-0319
Demain, 2011, Natural products for cancer chemotherapy, Microb. Biotechnol., 4, 687, 10.1111/j.1751-7915.2010.00221.x
Deng, 2018, Scutellarin inhibits human renal cancer cell proliferation and migration via upregulation of PTEN, Biomed. Pharmacother., 107, 1505, 10.1016/j.biopha.2018.08.127
dos Santos, 2012, Cisplatin-induced nephrotoxicity and targets of nephroprotection: an update, Arch. Toxicol., 86, 1233, 10.1007/s00204-012-0821-7
Feng, 2012, Novel function of scutellarin in inhibiting cell proliferation and inducing cell apoptosis of human Burkitt lymphoma Namalwa cells, Leuk. Lymphoma, 53, 2456, 10.3109/10428194.2012.693177
Fusco, 2020, PTEN alterations and their role in cancer management: are we making headway on precision medicine?, Genes, 11, 10.3390/genes11070719
Gao, 2017, Cytotoxic and chemosensitization effects of Scutellarin from traditional Chinese herb Scutellaria altissima L. in human prostate cancer cells, Oncol. Rep., 38, 1491, 10.3892/or.2017.5850
Gao, 2017, Therapeutic effects of breviscapine in cardiovascular diseases: a review, Front. Pharmacol., 8, 10.3389/fphar.2017.00289
Giménez-Bonafé, 2009, Overcoming drug resistance by enhancing apoptosis of tumor cells, Curr. Cancer Drug Targets, 9, 320, 10.2174/156800909788166600
Greten, 2019, Inflammation and cancer: triggers, mechanisms, and consequences, Immunity, 51, 27, 10.1016/j.immuni.2019.06.025
Groll, 1997, Structure of 20S proteasome from yeast at 2.4 A resolution, Nature, 386, 463, 10.1038/386463a0
Hagner, 2010, Cancer chemotherapy: targeting folic acid synthesis, Cancer Manag. Res., 2, 293
Han, 2021, EGR1 promoted anticancer effects of Scutellarin via regulating LINC00857/miR-150-5p/c-Myc in osteosarcoma, J. Cell Mol. Med., 25, 8479, 10.1111/jcmm.16809
Han, 2022, Design, synthesis of amide derivatives of scutellarin and their antileukemia and neuroprotective activities, Med. Chem. Res., 31, 905, 10.1007/s00044-022-02885-z
Han, 2017, Scutellarin derivatives as apoptosis inducers: design, synthesis and biological evaluation, Eur. J. Med. Chem., 135, 270, 10.1016/j.ejmech.2017.03.020
Harada, 2016, Histone deacetylase inhibitors in multiple myeloma: from bench to bedside, Int. J. Hematol., 104, 300, 10.1007/s12185-016-2008-0
Harjes, 2017, Antiangiogenic and tumour inhibitory effects of downregulating tumour endothelial FABP4, Oncogene, 36, 912, 10.1038/onc.2016.256
He, 2021, Combined scutellarin and C(18)H(17)NO(6) imperils the survival of glioma: partly associated with the repression of PSEN1/PI3K-AKT signaling Axis, Front. Oncol., 11
Hou, 2017, Scutellarin inhibits proliferation, invasion, and tumorigenicity in human breast cancer cells by regulating HIPPO-YAP signaling pathway, Med. Sci. Monit., 23, 5130, 10.12659/MSM.904492
Jiang, 2013, A novel polyrotaxane-based delivery system for scutellarin: preparation, characterization, and in vitro evaluation, Carbohydr. Res., 380, 149, 10.1016/j.carres.2013.07.009
Jin, 2011, Fibronectin and vitronectin induce AP-1-mediated matrix metalloproteinase-9 expression through integrin α5β1/αvβ3-dependent Akt, ERK and JNK signaling pathways in human umbilical vein endothelial cells, Cell. Signal., 23, 125, 10.1016/j.cellsig.2010.08.012
Kamada, 2002, Cyclodextrin conjugate-based controlled release system: repeated- and prolonged-releases of ketoprofen after oral administration in rats, J. Contr. Release, 82, 407, 10.1016/S0168-3659(02)00171-2
Ke, 2017, Scutellarin suppresses migration and invasion of human hepatocellular carcinoma by inhibiting the STAT3/Girdin/Akt activity, Biochem. Biophys. Res. Commun., 483, 509, 10.1016/j.bbrc.2016.12.114
Kertesz, 2006, The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth, Blood, 107, 2330, 10.1182/blood-2005-04-1655
Lee, 2019, Highlighted STAT3 as a potential drug target for cancer therapy, BMB Rep., 52, 415, 10.5483/BMBRep.2019.52.7.152
Li, 2021, Scutellarin inhibits the growth and EMT of gastric cancer cells through regulating PTEN/PI3K pathway, Biol. Pharm. Bull., 44, 780, 10.1248/bpb.b20-00822
Li, 2013, Potentiation of scutellarin on human tongue carcinoma xenograft by low-intensity ultrasound, PLoS One, 8
Li, 2013, Scutellarin inhibits the growth and invasion of human tongue squamous carcinoma through the inhibition of matrix metalloproteinase-2 and -9 and αvβ6 integrin, Int. J. Oncol., 42, 1674, 10.3892/ijo.2013.1873
Li, 2020, Scutellarin circumvents chemoresistance, promotes apoptosis, and represses tumor growth by HDAC/miR-34a-mediated down-modulation of Akt/mTOR and NF-κB-orchestrated signaling pathways in multiple myeloma, Int. J. Clin. Exp. Pathol., 13, 212
Li, 2019, Friend or foe, the role of EGR-1 in cancer, Med. Oncol., 37, 7, 10.1007/s12032-019-1333-6
Liao, 2015, Folic acid-polyamine-β-cyclodextrin for targeted delivery of scutellarin to cancer cells, Polym. Adv. Technol., 26, 487, 10.1002/pat.3477
Liberti, 2016, The Warburg effect: how does it benefit cancer cells?, Trends Biochem. Sci., 41, 211, 10.1016/j.tibs.2015.12.001
Liu, 2019, Scutellarin inhibits proliferation and invasion of hepatocellular carcinoma cells via down-regulation of JAK2/STAT3 pathway, J. Cell Mol. Med., 23, 3040, 10.1111/jcmm.14169
Longley, 2003, 5-fluorouracil: mechanisms of action and clinical strategies, Nat. Rev. Cancer, 3, 330, 10.1038/nrc1074
Lugano, 2020, Tumor angiogenesis: causes, consequences, challenges and opportunities, Cell. Mol. Life Sci., 77, 1745, 10.1007/s00018-019-03351-7
Lv, 2019, Scutellarin inhibits hypoxia-induced epithelial-mesenchymal transition in bladder cancer cells, J. Cell. Physiol., 234, 23169, 10.1002/jcp.28883
Matsunoshita, 2011, Suppression of osteosarcoma cell invasion by chemotherapy is mediated by urokinase plasminogen activator activity via up-regulation of EGR1, PLoS One, 6, 10.1371/journal.pone.0016234
Morozov, 2019, Proteasomes and several aspects of their heterogeneity relevant to cancer, Front. Oncol., 9, 761, 10.3389/fonc.2019.00761
Nabavi, 2020, Flavonoid biosynthetic pathways in plants: versatile targets for metabolic engineering, Biotechnol. Adv., 38, 10.1016/j.biotechadv.2018.11.005
Navashenaq, 2020, Doxil chemotherapy plus liposomal P5 immunotherapy decreased myeloid-derived suppressor cells in murine model of breast cancer, Nanomed. Nanotechnol. Biol. Med., 24, 10.1016/j.nano.2020.102150
Newman, 2016, Natural products as sources of new drugs from 1981 to 2014, J. Nat. Prod., 79, 629, 10.1021/acs.jnatprod.5b01055
Newman, 2020, Natural products as sources of new drugs over the nearly four decades from 01/1981 to 09/2019, J. Nat. Prod., 83, 770, 10.1021/acs.jnatprod.9b01285
Ni, 2018, Synthesis of scutellarein derivatives with a long aliphatic chain and their biological evaluation against human cancer cells, Molecules, 23, 10.3390/molecules23020310
Nik, 2019, Targeted-nanoliposomal combretastatin A4 (CA-4) as an efficient antivascular candidate in the metastatic cancer treatment, J. Cell. Physiol., 234, 14721, 10.1002/jcp.28230
Niu, 2015, Scutellarin protects against the liver injury induced by diosbulbin B in mice and its mechanism, J. Ethnopharmacol., 164, 301, 10.1016/j.jep.2015.02.031
Nurgali, 2018, Editorial: adverse effects of cancer chemotherapy: anything new to improve tolerance and reduce sequelae?, Front. Pharmacol., 9, 10.3389/fphar.2018.00245
Ohue, 2019, Regulatory T (Treg) cells in cancer: can Treg cells be a new therapeutic target?, Cancer Sci., 110, 2080, 10.1111/cas.14069
Panche, 2016, Flavonoids: an overview, J. Nutr. Sci., 5, e47, 10.1017/jns.2016.41
Partridge, 2001, Side effects of chemotherapy and combined chemohormonal therapy in women with early-stage breast cancer, J. Natl. Cancer Inst. Monogr., 135, 10.1093/oxfordjournals.jncimonographs.a003451
Pucci, 2019, Innovative approaches for cancer treatment: current perspectives and new challenges, Ecancermedicalscience, 13, 961, 10.3332/ecancer.2019.961
Rajala, 2016, The Warburg effect mediator pyruvate kinase M2 expression and regulation in the retina, Sci. Rep., 6, 10.1038/srep37727
Redza-Dutordoir, 2016, Activation of apoptosis signalling pathways by reactive oxygen species, Biochim. Biophys. Acta Mol. Cell Res., 1863, 2977, 10.1016/j.bbamcr.2016.09.012
Rodríguez-García, 2019, vol. 8
Schwartz, 2005, Targeting the cell cycle: a new approach to cancer therapy, J. Clin. Oncol., 23, 9408, 10.1200/JCO.2005.01.5594
Shabgah, 2021, Chemokine CXCL14; a double-edged sword in cancer development, Int. Immunopharm., 97
Shabgah, 2021, The role of Non-coding Genome in Cancer-associated Fibroblasts; state-of-the-art and perspectives in cancer targeted therapy, Curr. Drug Targets, 10.2174/1389450122666210216091953
Shabgah, 2021, CXC chemokine ligand 16: a Swiss army knife chemokine in cancer, Expet Rev. Mol. Med., 23
Shabgah, 2020, The role of non-coding genome in the behavior of infiltrated myeloid-derived suppressor cells in tumor microenvironment; a perspective and state-of-the-art in cancer targeted therapy
Shabgah, 2021, Curcumin and cancer; are long non-coding RNAs missing link?, Prog. Biophys. Mol. Biol.
Shi, 2019, Scutellarein selectively targets multiple myeloma cells by increasing mitochondrial superoxide production and activating intrinsic apoptosis pathway, Biomed. Pharmacother., 109, 2109, 10.1016/j.biopha.2018.09.024
Shibaguchi, 2011, Sonodynamic cancer therapy: a non-invasive and repeatable approach using low-intensity ultrasound with a sonosensitizer, Anticancer Res., 31, 2425
Sun, 2019, Renoprotective effect of scutellarin on cisplatin-induced renal injury in mice: impact on inflammation, apoptosis, and autophagy, Biomed. Pharmacother., 112, 10.1016/j.biopha.2019.108647
Szabo, 2016, Gasotransmitters in cancer: from pathophysiology to experimental therapy, Nat. Rev. Drug Discov., 15, 185, 10.1038/nrd.2015.1
Szejtli, 1998, Introduction and general overview of cyclodextrin chemistry, Chem. Rev., 98, 1743, 10.1021/cr970022c
Wang, 2014, Scutellarin inhibits high glucose-induced and hypoxia-mimetic agent-induced angiogenic effects in human retinal endothelial cells through reactive oxygen species/hypoxia-inducible factor-1α/vascular endothelial growth factor pathway, J. Cardiovasc. Pharmacol., 64, 218, 10.1097/FJC.0000000000000109
Wang, 2012, Antitumor activity of Dioscorea bulbifera L. rhizome in vivo, Fitoterapia, 83, 388, 10.1016/j.fitote.2011.12.001
Wang, 2018, Clinical benefits and pharmacology of scutellarin: a comprehensive review, Pharmacol. Ther., 190, 105, 10.1016/j.pharmthera.2018.05.006
Wu, 2013, Baicalin and scutellarin are proteasome inhibitors that specifically target chymotrypsin-like catalytic activity, Phytother Res., 27, 1362, 10.1002/ptr.4878
Xu, 2013, Scutellarin-induced apoptosis in HepG2 hepatocellular carcinoma cells via a STAT3 pathway, Phytother Res., 27, 1524, 10.1002/ptr.4892
Yang, 2013, Scutellarin-cyclodextrin conjugates: synthesis, characterization and anticancer activity, Carbohydr. Polym., 92, 1308, 10.1016/j.carbpol.2012.10.012
You, 2017, Scutellarin inhibits Hela cell growth and glycolysis by inhibiting the activity of pyruvate kinase M2, Bioorg. Med. Chem. Lett, 27, 5404, 10.1016/j.bmcl.2017.11.011
Zeng, 2021, Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade, Eur. J. Pharmacol., 906, 10.1016/j.ejphar.2021.174253
Zeng, 2022, Suppression of colitis-associated colorectal cancer by scutellarin through inhibiting Hedgehog signaling pathway activity, Phytomedicine, 98, 10.1016/j.phymed.2022.153972
Zhang, 2021, Scutellarin-induced A549 cell apoptosis depends on activation of the transforming growth factor-β1/smad2/ROS/caspase-3 pathway, Open Life Sci., 16, 961, 10.1515/biol-2021-0085
Zhang, 2005, The anti-HIV-1 effect of scutellarin, Biochem. Biophys. Res. Commun., 334, 812, 10.1016/j.bbrc.2005.06.166
Zhang, 2010, Hydrophobic pharmaceuticals mediated self-assembly of β-cyclodextrin containing hydrophilic copolymers: novel chemical responsive nano-vehicles for drug delivery, J. Contr. Release, 145, 116, 10.1016/j.jconrel.2010.04.019
Zhu, 2017, Scutellarin suppresses human colorectal cancer metastasis and angiogenesis by targeting ephrinb2, Am. J. Transl. Res., 9, 5094
Zolochevska, 2012, Advances in sonoporation strategies for cancer, Front. Biosci., 4, 988
Zou, 2020, Targeting STAT3 in cancer immunotherapy, Mol. Cancer, 19, 145, 10.1186/s12943-020-01258-7