Four clusters of Trichostrongylus infection diagnosed in a single center, in Italy
Tóm tắt
Trichostrongylus spp. are parasites that are seldom recognized as a cause of eosinophilia and gastroenteric symptoms in industrialized countries. The index of suspicion raises when several members of a same household present eosinophilia. We report four clusters of Trichostrongylus infection diagnosed in a single center, in northern Italy. Patients came from four different provinces of three Italian Regions. Some patients presented symptoms (abdominal pain and diarrhea were the most frequent ones, reported by 67 and 42% of our patients, respectively), while other were asymptomatic. All of them presented eosinophilia, that was severe (>5000 eosinophils/mmc) in 58% cases. Obtaining an accurate history from patients, investigating possible ingestion of vegetables contaminated by organic manure or sheep dejections, is particularly important to achieve diagnosis, also in light of the low sensitivity of parasitological tests.
Tài liệu tham khảo
Phosuk I, Intapan PM, Sanpool O, Janwan P, Thanchomnang T, Sawanyawisuth K, Morakote N, Maleewong W. Molecular evidence of Trichostrongylus colubriformis and Trichostrongylus axei infections in humans from Thailand and Lao PDR. Am J Trop Med Hyg. 2013;89:376–9.
Cancrini G, Boemi G, Iori A, Corselli A. Human infestations by Trichostrongylus axei, T. capricola and T. vitrinus: 1st report in Italy. Parassitologia. 1982;24:145–9.
Lattes S, Ferte H, Delaunay P, Depaquit J, Vassallo M, Vittier M, Kokcha S, Coulibaly E, Marty P. Trichostrongylus colubriformis nematode infections in humans, France. Emerg Infect Dis. 2011;17:1301–2.
Thibert JB, Guiguen C, Gangneux JP. Human trichostrongyloidosis: case report and microscopic difficulties to identify ankylostomidae eggs. Ann Biol Clin. 2006;64:281–5.
Wall EC, Bhatnagar N, Watson J, Doherty T. An unusual case of hypereosinophilia and abdominal pain: an outbreak of Trichostrongylus imported from New Zealand. J Travel Med. 2011;18:59–60.
The Centers for Disease Control and Prevention. Trichostrongylosis. http://www.cdc.gov/dpdx/trichostrongylosis/tx.html. Accessed 27 Sept 2016.
Watthanakulpanich D, Pongvongsa T, Sanguankiat S, Nuamtanong S, Maipanich W, Yoonuan T, Phuphisut O, Boupha B, Moji K, Sato M, et al. Prevalence and clinical aspects of human Trichostrongylus colubriformis infection in Lao PDR. Acta Trop. 2013;126:37–42.
Sato M, Yoonuan T, Sanguankiat S, Nuamtanong S, Pongvongsa T, Phimmayoi I, Phanhanan V, Boupha B, Moji K, Waikagul J. Short report: human Trichostrongylus colubriformis infection in a rural village in Laos. Am J Trop Med Hyg. 2011;84:52–4.
Cringoli G, Rinaldi L. Water as risk factor for helminthiasis in domestic ruminants in the central and southern Italy and zoonotic risk. Annali di igiene: medicina preventia e di comunita. 2003;15:43–6.
Center for Tropical Diseases. Agar plate coproculture. http://www.tropicalmed.eu/Page/WebObjects/PageTropE.woa/wa/displayPage?name=Method+Coproculture. Accessed 27 Sept 2016.
World Health Organization. Manual of basic techniques for a health laboratory. 2nd ed. Geneva: WHO; 2003.
Yong TS, Lee JH, Sim S, Lee J, Min DY, Chai JY, Eom KS, Sohn WM, Lee SH, Rim HJ. Differential diagnosis of Trichostrongylus and hookworm eggs via PCR using ITS-1 sequence. Korean J Parasitol. 2007;45:69–74.