Fornix lesions: Effects on active and passive avoidance behavior
Tóm tắt
Twenty-four fornix-lesioned and 16 sham-operated rats were tested on one-way active avoidance acquisition, subsequent passive avoidance of the previously safe compartment, and acquisition and extinction of the passive avoidance of an electrified foodcup. Rats with lesions of the fornix made significantly more errors than controls in learning the one-way active avoidance acquisition task and had significantly elevated freezing scores on both escape and avoidance trials. Lesioned animals also made significantly more errors in the passive avoidance of the previously safe compartment. There were no significant differences found on either acquisition or extinction of the passive avoidance of an electrified foodcup. The results support the hypothesis that fornix destruction produces impaired performance on tasks which require a spatial discrimination.
Tài liệu tham khảo
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