Food Insecurity May be an Independent Risk Factor Associated With Erectile Dysfunction in the United States: Analysis of the National Health and Nutrition Examination Survey Data

Sexual Medicine - Tập 10 - Trang 100549 - 2022
Wei Wang1,2, Jiawei Chen2, Liao Peng2, Xiaoshuai Gao2, Lede Lin2, Yang Xiong1,2, Fuxun Zhang1,2, Yucheng Ma2, Feng Qin1, Jiuhong Yuan1,2
1Andrology Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan, China
2Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China

Tóm tắt

AbstractIntroductionWhile food insecurity is a global public health problem associated with obesity, diabetes, hypertension and coronary heart disease, literature regarding the relationship between food insecurity and erectile dysfunction (ED) is scarce.AimWe aimed to determine the associations between food insecurity and ED in the National Health and Nutrition Examination Survey.MethodsData was extracted from 3,891 participants (aged ≥ 20 years) with ED in the 2001–2004 National Health and Nutrition Examination Survey. Multivariable logistic regression analysis with sampling weights was conducted to evaluate the associations.Main outcome measureFood security was assessed utilizing the Household Food Security Module. A single-question self-report from the Massachusetts Male Aging Study was utilized to evaluate ED status.ResultsApproximately 10.2% of individuals had food insecurity. Food insecurity was significantly associated with ED after full adjustment (odds ratio [OR] 1.56; 95% confidence interval [95% CI] 1.16–2.09; P = .003). Men with very low food insecurity had 59% higher risks of ED compared with those having high food security (OR 1.59; 95% CI 1.13–2.27; P = .006). Moreover, the associations were stronger in the old people (age ≥ 60) (OR 2.15; 95% CI 1.26–3.66; P = .004).ConclusionsFood insecurity might be associated with higher risks of developing ED.

Tài liệu tham khảo

McCabe, 2016, Definitions of sexual dysfunctions in women and men: a consensus statement from the fourth international consultation on sexual medicine 2015, J Sex Med, 13, 135, 10.1016/j.jsxm.2015.12.019 Peak, 2015, Emerging drugs for the treatment of erectile dysfunction, Expert Opin Emerging Drugs, 20, 263, 10.1517/14728214.2015.1021682 Nguyen, 2017, Erectile dysfunction in young men-a review of the prevalence and risk factors, Sex Med Rev, 5, 508, 10.1016/j.sxmr.2017.05.004 Miner, 2019, Erectile dysfunction and subclinical cardiovascular disease, Sex Med Rev, 7, 455, 10.1016/j.sxmr.2018.01.001 Dong, 2011, Erectile dysfunction and risk of cardiovascular disease: meta-analysis of prospective cohort studies, J Am Coll Cardiol, 58, 1378, 10.1016/j.jacc.2011.06.024 Pollard, 2019, Food insecurity and hunger in rich countries-it is time for action against inequality, Int J Environ Res Public Health, 16, 1804, 10.3390/ijerph16101804 Wolfson, 2020, Food insecurity and COVID-19: disparities in early effects for US adults, Nutrients, 12, 1648, 10.3390/nu12061648 Banerjee, 2017, Food insecurity, CKD, and subsequent ESRD in US adults, Am J Kidney Dis, 70, 38, 10.1053/j.ajkd.2016.10.035 Golovaty, 2020, Food insecurity may be an independent risk factor associated with nonalcoholic fatty liver disease among low-income adults in the United States, J Nutr, 150, 91, 10.1093/jn/nxz212 Liu, 2021, Food insecurity and cardiovascular disease risk, Curr Atheroscler Rep, 23, 24, 10.1007/s11883-021-00923-6 Portela-Parra, 2019, Food insecurity is associated with lower cognitive functioning in a national sample of older adults, J Nutr, 149, 1812, 10.1093/jn/nxz120 Curtin, 2013, National Health and Nutrition Examination Survey: sample design, 2007-2010, Vital Health Stat 2, 1 United States Department of Agriculture Economic Research Service, 2022, Definitions of food security O'Donnell, 2005, The validity of a single-question self-report of erectile dysfunction. Results from the Massachusetts male aging study, J Gen Intern Med, 20, 515, 10.1111/j.1525-1497.2005.0076.x Farag, 2016, Vitamin D deficiency is independently associated with greater prevalence of erectile dysfunction: the national health and nutrition examination survey (NHANES) 2001-2004, Atherosclerosis, 252, 61, 10.1016/j.atherosclerosis.2016.07.921 Lopez, 2017, Association of urinary phthalate metabolites with erectile dysfunction in racial and ethnic groups in the national health and nutrition examination survey 2001-2004, Am J Men's Health, 11, 576, 10.1177/1557988316641370 Loprinzi, 2015, Association between objectively measured physical activity and erectile dysfunction among a nationally representative sample of American men, J Sex Med, 12, 1862, 10.1111/jsm.12977 Skeldon, 2015, Erectile dysfunction and undiagnosed diabetes, hypertension, and hypercholesterolemia, Ann Fam Med, 13, 331, 10.1370/afm.1816 Sun, 2020, Food insecurity is associated with cardiovascular and all-cause mortality among adults in the United States, J Am Heart Assoc, 9, 10.1161/JAHA.119.014629 Echeverri Tirado, 2016, Aging and erectile dysfunction, Sex Med Rev, 4, 63, 10.1016/j.sxmr.2015.10.011 Beacom, 2021, Investigating food insecurity measurement globally to inform practice locally: a rapid evidence review, Crit Rev Food Sci Nutr, 61, 3319, 10.1080/10408398.2020.1798347 Vercammen, 2019, Food security and 10-year cardiovascular disease risk among U.S. adults, Am J Prev Med, 56, 689, 10.1016/j.amepre.2018.11.016 Smith, 2020, Food insecurity, acculturation and diagnosis of CHD and related health outcomes among immigrant adults in the USA, Public Health Nutr, 23, 416, 10.1017/S1368980019001952 Venci, 2018, Functional limitation and chronic diseases are associated with food insecurity among U.S. adults, Ann Epidemiol, 28, 182, 10.1016/j.annepidem.2018.01.005 Vos, 2017, Added sugars and cardiovascular disease risk in children: a scientific statement from the American Heart Association, Circulation, 135, e1017, 10.1161/CIR.0000000000000439 La Favor, 2013, Erectile dysfunction precedes coronary artery endothelial dysfunction in rats fed a high-fat, high-sucrose, Western pattern diet, J Sex Med, 10, 694, 10.1111/jsm.12001 Zhu, 2018, Anti-inflammatory effects of phytochemicals from fruits, vegetables, and food legumes: a review, Crit Rev Food Sci Nutr, 58, 1260, 10.1080/10408398.2016.1251390 Shiri, 2006, Association between comorbidity and erectile dysfunction in patients with diabetes, Int J Impot Res, 18, 348, 10.1038/sj.ijir.3901432 Esposito, 2006, Dietary factors in erectile dysfunction, Int J Impot Res, 18, 370, 10.1038/sj.ijir.3901438 McClain, 2018, Food insecurity and odds of high allostatic load in Puerto Rican adults: the role of participation in the supplemental nutrition assistance program during 5 years of follow-up, Psychosom Med, 80, 733, 10.1097/PSY.0000000000000628 Rosen, 2001, Psychogenic erectile dysfunction. Classification and management, Urol Clin North Am, 28, 269, 10.1016/S0094-0143(05)70137-3 Tucher, 2021, Conceptualizing food insecurity among older adults: development of a summary indicator in the National Health and Aging Trends Study, J Gerontol B Psychol Sci Soc Sci, 76, 2063, 10.1093/geronb/gbaa147 Afulani, 2015, Food insecurity and health outcomes among older adults: the role of cost-related medication underuse, J Nutr Gerontol Geriatr, 34, 319, 10.1080/21551197.2015.1054575