Folic acid mediated attenuation of loss of heterozygosity of DCC tumor suppressor gene in the colonic mucosa of patients with colorectal adenomas

Cancer Detection and Prevention - Tập 27 - Trang 297-304 - 2003
Kiran K Nagothu1, Richard Jaszewski1,2, Lathika Moragoda1, Arun K Rishi1,2,3, Raphaela Finkenauer2, Martin Tobi1,2, Jo Ann Naumoff2, Ravi Dhar1, Murray Ehrinpreis1, Omer Kucuk1,3, Adhip P.N Majumdar1,2,3,4
1Department of Internal Medicine, Wayne State University School of Medicine, Detroit, MI 48201, USA
2Veterans Affairs Medical Center, Wayne State University School of Medicine, Detroit, MI 48201, USA
3Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA
4Department of Biochemistry and Molecular Biology, Wayne State University, School of Medicine, Detroit, MI 48201 USA

Tài liệu tham khảo

Giovannucci, 1993, Folate, methionine and alcohol intake and risk of colorectal adenoma, J. Natl. Cancer Inst., 85, 846, 10.1093/jnci/85.11.875 Willet, 1994, Micronutrients and cancer risk, Am. J. Clin. Nutr., 59, 1162s, 10.1093/ajcn/59.5.1162S Cravo, 1992, Folate deficiency enhances the development of colonic neoplasia in dimethylhydrazine-treated rats, Cancer Res., 52, 5002 Benito, 1991, Nutritional factors in colorectal cancer risk: a case-control study in Majorca, Int. J. Cancer, 49, 161, 10.1002/ijc.2910490202 Freudenheim, 1991, Folate intake and carcinogenesis of the colon and rectum, Int. J. Epidemiol., 20, 368, 10.1093/ije/20.2.368 Bird, 1995, Red cell and plasma folate, folate consumption, and the risk of colorectal adenomatous polyps, Cancer Epidemol. Biomark. Prev., 4, 709 Tseng, 1996, Micronutrients and the risk of colorectal adenomas, Am. J. Epidemol., 144, 1005, 10.1093/oxfordjournals.aje.a008871 Meenan, 1997, Epithelial cell folate depletion occurs in neoplastic but not adjacent normal colon mucosa, Gastroenterology, 112, 1163, 10.1016/S0016-5085(97)70127-6 Kim, 1994, Dietary folate protects against the development of macroscopic colonic neoplasms in a dose-dependent manner in the dimethyl-hydrazine rat model, Gastroenterology, 106, A402 Wargovich, 2000, Efficacy of potential chemopreventive agents on rat colon aberrant crypt formation and progression, Carcinogenesis, 21, 1149, 10.1093/carcin/21.6.1149 Roncucci, 1991, Identification and quantification of aberrant crypt foci and microadenomas in the human colon, Hum. Pathol., 22, 287, 10.1016/0046-8177(91)90163-J Roncucci, 1991, Classification of aberrant crypt foci and microadenomas in human colon, Cancer Epidemiol. Biomark. Prev., 1, 57 Jaszewski, 1999, Folic acid inhibition of EGFR-mediated proliferation in human colon cancer cell lines, Am. J. Physiol. Cell Physiol., 277, C1142, 10.1152/ajpcell.1999.277.6.C1142 Akoglu, 2000, Folate and chemoprevention of colorectal cancer: is 5-methyltetrahydrofolate an active antiproliferative agent in folate-treated colon cancer cells, Nutrition, 17, 652, 10.1016/S0899-9007(01)00594-9 Fearon, 1992, Genetic alterations underlying colorectal tumorigenesis, Cancer Surv., 12, 119 Fearon, 1990, A genetic model for colorectal tumorigenesis, Cell, 61, 759, 10.1016/0092-8674(90)90186-I Miyoshi, 1992, Somatic mutations of the APC gene in colorectal tumors: mutation cluster region of the APC gene, Hum. Mol. Genet., 1, 229, 10.1093/hmg/1.4.229 Fearon, 1990, Identification of a chromosome 18q gene that is altered in colorectal carcinoma, Science, 247, 49, 10.1126/science.2294591 Baker, 1989, Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas, Science, 244, 217, 10.1126/science.2649981 Lipkin, 1987, Biomarker of increased susceptibility to gastrointestinal cancer: their development and application to studies of cancer prevention, Gastroenterology, 92, 1083, 10.1016/0016-5085(87)90987-5 Majumdar, 1996, Inhibition of gastric mucosal regeneration by tyrphostin: evaluation of the role of epidermal growth factor receptor tyrosine kinase, J. Lab. Clin. Med., 128, 173, 10.1016/S0022-2143(96)90009-8 Tandle, 2000, Infrequent loss of heterozygosity at adenomatous polyposis coli gene locus in Indian oral cancers, Cancer Lett., 157, 155, 10.1016/S0304-3835(00)00484-5 Ara, 1990, Codon 72 polymorphism of the TP53 gene, Nucleic Acids Res., 18, 4961, 10.1093/nar/18.16.4961 Gao, 1993, Frequent loss of expression and loss of heterozygosity of the putative tumor suppressor gene DCC in prostatic carcinomas, Cancer Res., 53, 2723 Maesawa, 1995, The sequential accumulation of genetic alterations characteristic of the colorectal adenoma-carcinoma sequence does not occur between gastric adenoma and adenocarcinoma, J. Pathol., 176, 249, 10.1002/path.1711760307 Xiao, 2001, Increased in vitro activation of EGFR by membrane-bound TGF-α from gastric and colonic mucosa of aged rats, Am. J. Physiol. Gastrointest. Liver Physiol., 281, G111, 10.1152/ajpgi.2001.281.1.G111 Hamilton, 1993, The molecular genetics of colorectal neoplasia, Gastroenterology, 105, 3, 10.1016/0016-5085(93)90003-U Hedrick, 1994, The DCC gene product in cellular differentiation and colorectal tumorigenesis, Genes Dev., 8, 1174, 10.1101/gad.8.10.1174 Saito, 1999, Expression of DCC protein in colorectal tumors and its relationship to tumor progression and metastasis, Oncology, 56, 134, 10.1159/000011954 Jacob, 1998, Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women, J. Nutr., 128, 1204, 10.1093/jn/128.7.1204 Blount, 1997, Folic acid deficiency causes misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage, Proc. Natl. Acad. Sci. U.S.A., 94, 3290, 10.1073/pnas.94.7.3290 Weinberg, 1981, Mutator phenotypes in mammalian cell mutants with distinct biochemical defects and abnormal deoxyribinucleoside triphosphate pools, Proc. Natl. Acad. Sci. U.S.A., 78, 2447, 10.1073/pnas.78.4.2447 Fenech, 1944, The relationship between micronuclei in human lymphocytes and plasma levels of Vitamins C, E, B12, and folic acid, Carcinogenesis, 15, 1405, 10.1093/carcin/15.7.1405 James, 1994, In vitro folate deficiency induces deoxynucleotide pool imbalance, apoptosis, and mutagenesis in Chinese hamster ovary cells, Cancer Res., 94, 5057 Cravo, 1993, Folate supplementation increases the degree of DNA methylation in patients with colonic neoplasms, Gastroenetrology, 104, A394 Nensey, 1995, Aging: increased responsiveness of colorectal mucosa to carcinogen stimulation and protective role of folic acid, Dig. Dis. Sci., 40, 396, 10.1007/BF02065427 Yarden, 1988, Growth factor receptor tyrosine kinases, Annu. Rev. Biochem., 57, 443, 10.1146/annurev.bi.57.070188.002303 Malecka-Panas, 1997, Differential activation of total and EGF receptor (EGF-R) tyrosine kinase (Tyr-k) in the rectal mucosa in patients with adenomatous polyps, ulcerative colitis and colon cancer, Hapatogastroenterology, 44, 435 Relan, 1995, Identification and evaluation of the role of endogenous tyrosine kinases in azoxymethane induction of proliferative processes in the colonic mucosa of rats, Biochim. Biophys. Acta, 1244, 368, 10.1016/0304-4165(95)00024-6 Barnard, 1995, Epidermal growth factor-related peptides and their relevance to gastrointestinal pathophysiology, Gastroenterology, 108, 564, 10.1016/0016-5085(95)90087-X Marshall, 1991, Tumor suppressor genes, Cell, 64, 313, 10.1016/0092-8674(91)90641-B Rhyu, 1994, Allelic deletions in of MCC/APC and p53 are frequent late events in human gastric carcinogenesis, Gastroenterology, 106, 1584, 10.1016/0016-5085(94)90414-6 Martinez, 1999, Risk factors for Ki-ras protooncogene mutation in sporadic colorectal adenomas, Cancer Res., 59, 5181 Hagmar L, Bonassi S, Stromberg U, Brogger A, Knudsen LE, Norppa H, et al. Chromosomal aberrations in lymphocytes predict human cancer: a report from European Study Group on Cytogenetic Biomarkers and Health (ESCH). Cancer Res 1998;4117–21. Bonassi, 2000, Chromosomal aberrations in lymphocytes predict human cancer independently of exposure to carcinogens: European Study Group on Cytogenetic Biomarkers and Health, Cancer Res., 60, 1619 Sato, 2001, Frequent loss of expression without sequence mutations of the DCC gene in primary gastric cancer, Br. J. Cancer, 85, 199, 10.1054/bjoc.2001.1888 Deng, 1999, Methylation of CpG in a small region of the MLH1 promoter invariably correlates with the absence of gene expression, Cancer Res., 59, 2029