Flavonoids from Tetrastigma obtectum enhancing glucose consumption in insulin-resistance HepG2 cells via activating AMPK

Song, 2003, The survey of Tujia ethnic medicines (Vitaceae) in Hubei, Chin J Ethnomed Ethnopharm, 61, 117 Liu, 2002, New C-glycosyl flavones from Tetrastigma hemsleyanum (Vitaceae), Acta Bot Sin, 44, 227 Yang, 1998, Chemical constituents of Tetrastigma hemsleyanum Diels. Et Gilg, China J Chin Mater Med, 23, 419 Liu, 2003, Studies on chemical constituents from Tetrastigma hypoglaucum, Chin Tradit Herb Drugs, 34, 4 Hossain, 2011, In vitro total phenolics, flavonoids contents and antioxidant activity of essential oil, various organic extracts from the leaves of tropical medicinal plant Tetrastigma from Sabah, Asian Pac J Trop Med, 4, 717, 10.1016/S1995-7645(11)60180-6 Attele, 2002, Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component, Diabetes, 51, 1851, 10.2337/diabetes.51.6.1851 Rates, 2001, Plants as source of drugs, Toxicon, 39, 603, 10.1016/S0041-0101(00)00154-9 Sheehan, 2003, Current therapeutic options in type 2 diabetes mellitus: a practical approach, Clin Med Res, 1, 189, 10.3121/cmr.1.3.189 Meier, 2008, Use of thiazolidinediones and fracture risk, Arch Intern Med, 168, 820, 10.1001/archinte.168.8.820 Yaturu, 2007, Thiazolidinedione treatment decreases bone mineral density in type 2 diabetic men, Diabetes Care, 30, 1574, 10.2337/dc06-2606 Kola, 2008, Obesity and metabolism, Front Horm Res Basel, Karger, 36, 198, 10.1159/000115366 Xie, 2006, Effect of ethanolic extracts of Ananas comosus L. leaves on insulin sensitivity in rats and HepG2, Comp Biochem Physiol, 143, 429 Lin, 2008, Epigallocatechin gallate (EGCG) attenuates high glucose-induced insulin signaling blockade in human hepG2 hepatoma cells, Mol Nutr Food Res, 52, 930, 10.1002/mnfr.200700437 Luo, 2009, Resistin induces insulin resistance by both AMPK-independent mechanisms in HepG2 cells, Endocrine, 36, 60, 10.1007/s12020-009-9198-7 Lin, 2007, Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells, J Lipid Res, 48, 2334, 10.1194/jlr.M700128-JLR200 Koistinen, 2003, 5-Amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes, Diabetes, 52, 1066, 10.2337/diabetes.52.5.1066 Ben, 2008, The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level, Oncogene, 27, 3576, 10.1038/sj.onc.1211024 Ahn, 2008, The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways, Biochem Biophys Res Commun, 373, 545, 10.1016/j.bbrc.2008.06.077 Martínez de Morentin, 2010, AMP-activated protein kinase: ‘a cup of tea’ against cholesterol-induced neurotoxicity, J Pathol, 222, 329, 10.1002/path.2778 Lu, 2010, Quercetin activates AMP-activated protein kinase by reducing PP2C expression protecting old mouse brain against high cholesterol-induced neurotoxicity, J Pathol, 222, 199, 10.1002/path.2754 Qin, 2011, Synthesis and biological activity of novel tiliroside derivants, Eur J Med Chem, 46, 5189, 10.1016/j.ejmech.2011.07.059 Zhai, 2012, Alkaloids from Pachysandra terminalis inhibit breast cancer invasion and have potential for development as antimetastasis therapeutic agents, J Nat Prod, 75, 1305, 10.1021/np300207c Zhao, 2007, Phytochemical investigation of Turnera diffusa, J Nat Prod, 70, 289, 10.1021/np060253r Ren, 2009, Studies on chemical constituents from Stenoloma chusanum (L.) Ching (II), Chin. Tradit. Herbal Drugs, 40, 104 Tovar-Gijón, 2006, A new C-glycosylflavone from Encyclia michuacana, J Mol Struct, 783, 96, 10.1016/j.molstruc.2005.08.024 Tsutomu, 1999, C-glycosidic flavonoids from Cassia occidentalis, Phytochemistry, 52, 1379, 10.1016/S0031-9422(99)00437-9 Xie, 2003, Flavone C-glycosides from Viola yedoensis MAKINO, Chem Pharm Bull, 51, 1204, 10.1248/cpb.51.1204 Ding, 1999, A novel flavonoid glycoside from Drymaria diandra, Planta Med, 65, 578, 10.1055/s-2006-960831 Wang, 2008, Flavonoids with iNOS inhibitory activity from Pogonatherum crinitum, J Ethnopharmacol, 118, 71, 10.1016/j.jep.2008.03.005 Zhang, 2005, Chemical constituents from Lithospermum zollingeri, Chin J Nat Med, 3, 357 Guo, 1998, The constituents from Lysimachia congestiflora, Nat Prod Res Dev, 4, 12 O'Neill, 2013, AMPK and exercise: glucose uptake and insulin sensitivity, Diabetes Metab J, 37, 1, 10.4093/dmj.2013.37.1.1 Liu, 2011, Reduction of lipid accumulation in HepG2 cells by luteolin is associated with activation of AMPK and mitigation of oxidative stress, Phytother Res, 25, 588, 10.1002/ptr.3305 Ha, 2010, The selected flavonol glycoside derived from Sophorae flos improves glucose uptake and inhibits adipocyte differentiation via activation AMPK in 3T3-L1 cells, Bioorg Med Chem Lett, 20, 6076, 10.1016/j.bmcl.2010.08.054 Zygmunt, 2010, Naringenin, a citrus flavonoid, increases muscle cell glucose uptake via AMPK, Biochem Biophys Res Commun, 398, 178, 10.1016/j.bbrc.2010.06.048 Zhang, 2010, 7-O-methylaromadendrin stimulates glucose uptake and improves insulin resistance in vitro, Biol Pharm Bull, 33, 1494, 10.1248/bpb.33.1494