Flavonoid VI-16 protects against DSS-induced colitis by inhibiting Txnip-dependent NLRP3 inflammasome activation in macrophages via reducing oxidative stress

Mucosal Immunology - Tập 12 - Trang 1150-1163 - 2019
Yue Zhao1, Qinglong Guo1, Qin Zhu1, Renxiang Tan2, Dongsheng Bai1, Xiumin Bu1, Binyan Lin1, Kai Zhao1, Chuyue Pan1, Haiyan Chen3, Na Lu1
1State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Basic Medicine, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, 210009, Nanjing, PR China
2State Key Laboratory Cultivation Base for TCM Quality and Efficacy, Nanjing University of Chinese Medicine, 138 Xinlin Road, 210023, Nanjing, PR China
3State Key Laboratory of Natural Medicines, Department of Biomedical Engineering, School of Engineering, China Pharmaceutical University, 24 Tongjiaxiang, 210009, Nanjing, PR China

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