Flash glucose monitoring and glycemic control in type 1 diabetes with subcutaneous insulin infusion

Acta Diabetologica - Tập 59 - Trang 509-515 - 2021
Sara Lomelino Pinheiro1, Margarida Bastos2, Luísa Barros2, Miguel Melo2, Isabel Paiva2
1Department of Endocrinology, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal
2Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal

Tóm tắt

To analyze the association between scan frequency and glycemic measures in continuous subcutaneous insulin infusion (CSII) treated type 1 diabetes (T1DM) adults. This retrospective study included 140 patients (> 18 years) with T1DM who used flash glucose monitoring (FGM). For each patient, we analyzed the Ambulatory Glucose Profile data over a period of 90 days. Data regarding glucose management indicator (GMI), time above, below and within range (TIR) and coefficient of variation (CV) were correlated with the number of daily scans. The effect of each additional test on glucose parameters was also evaluated. Users performed a mean of 8.6 ± 4.4 scans per day. There was an inverse correlation between scanning frequency and GMI (r = − 0.431, p < 0.001), CV (r = − 0.440, p < 0.001), time above and below range (r = − 0.446, p < 0.001 and r = − 0.200, p = 0.018, respectively). The number of daily scans correlated positively with TIR (r = 0.554, p < 0.001). For each additional scan per day, the mean GMI decreased 0.09% and TIR increased 1.60%. In patients with T1DM and CSII, higher rates of scanning correlated with improved glycemic markers, including reduced GMI and CV and increased TIR. For each test performed, there was a significant effect on the improvement of all glucose parameters.

Tài liệu tham khảo

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