First insights into the biochemistry ofSabella spallanzanii(Annelida: Polychaeta) mucus: a potentially unexplored resource for applicative purposes

Journal of the Marine Biological Association of the United Kingdom - Tập 91 Số 1 - Trang 199-208 - 2011
Loredana Stabili1,2, Luigi Musco2, Angela Di Benedetto3, Alessandro Merendino4, Luciano Villanova4, Adriana Giangrande1
1Dipartimento di Scienze e Tecnologie Biologiche ed Ambientali, Università del Saliento, 73100 (Lecce), Italy
2Istituto per l'Ambiente Marino Costiero, Sezione di Taranto
3Dipartimento di Chimica e CIRCC, Università degli Studi di Bari, Campus Universitario, 70126 Bari, Italy
4Lachifarma s.r.l. Laboratorio Chimico Farmaceutico, Dipartimento Ricerca & Sviluppo S.S. 16 Zona Industriale, 73010 Zollino (Lecce), Italy

Tóm tắt

Although mucus plays many different roles among marine invertebrates, relatively little is known about the link between biochemical structure and function. In the present study we focused on some physical and chemical properties of the polychaeteSabella spallanzanii's mucus such as viscosity, osmolarity, electrical conductivity, elemental composition, the protein and carbohydrate content, the total lipids and fatty acid composition, and polychlorinated biphenyls (PCBs) contamination. Moreover, an antimicrobial activity of the mucus was investigated. The water content ofS. spallanzaniimucus was 96.2±0.3%. By dry weight 26±1.2% was protein, 8±0.21% was carbohydrate and only 0.1% lipid, much of the remainder of the dry weight was inorganic (about 65.2%). The estimated PCBs content was <0.005 μg g−1. The mucus ofS. spallanzaniiexerted a natural lysozyme-like activity and producedin vitrothe growth inhibition ofVibrio anguillarum, Vibrio harveyi, Pseudomonas aeruginosaandCandida albicans.The findings from this study contribute to improve the limited knowledge available on the mucus composition in invertebrates and have implications for future investigations related to employment ofS. spallanzaniimucus as a source of compounds of pharmaceutical and marine technological interest.

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Journal of the Marine Biological Association of the United Kingdom

Tập 91 Số 1

199-208

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