Đặc điểm đầu tiên của virus parvovirus chó gây bệnh chết người ở coatis (Nasua nasua)

Archives of Virology - Tập 164 - Trang 3073-3079 - 2019
Danilo Bucafusco1,2, Hernán Argibay2,3, Leandro Diaz1, Celina Vega2,4, Leonardo Minatel5, Gabriela C. Postma5, Miguel Rinas6, Ana Bratanich1
1Cátedra de Virología, Universidad de Buenos Aires, Facultad de Ciencias Veterinarias, Ciudad Autónoma de Buenos Aires, Argentina
2Consejo Nacional de Investigaciones Científicas y Técnicas, Ciudad Autónoma de Buenos Aires, Argentina
3Instituto de Ecología, Genética y Evolución de Buenos Aires, Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Ciudad Autónoma de Buenos Aires, Argentina
4Instituto de Virología, Instituto Nacional de Tecnología Agropecuaria, Hurlingham, Argentina
5Cátedra de Patología Básica, Universidad de Buenos Aires, Facultad de Ciencias Veterinarias, Ciudad Autónoma de Buenos Aires, Argentina
6Parque Ecológico “El Puma”, Ministerio de Ecología, Candelaria, Argentina

Tóm tắt

Một virus giống như parvovirus chó (CPV) đã được phát hiện qua phương pháp PCR và được phân lập từ những con coati chết tại Argentina. Phân tích trình tự gen đầy đủ cho thấy virus này tương tự như CPV nhưng cũng chứa một đột biến trong protein VP2 (Arg377Ser) chưa được mô tả trước đây. Đây là báo cáo đầu tiên về virus giống CPV gây ra bệnh lý lâm sàng ở coatis. Độ tương đồng di truyền với các virus CPV-2c được phát hiện ở Brazil cho thấy mối quan hệ chặt chẽ giữa các virus này. Mặc dù tiềm năng gây bệnh của các chủng tương tự như CPV và virus panleukopenia mèo (FPV) ở động vật hoang dã vẫn chưa được hiểu một cách hoàn toàn, nghiên cứu này nhấn mạnh tầm quan trọng của các virus parvovirus như một mối đe dọa đối với động vật hoang dã nếu có điều kiện thích hợp.

Từ khóa

#virus parvovirus chó #coatis #bệnh lý lâm sàng #mối quan hệ di truyền #động vật hoang dã

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