Fine-Tuning of Chemotactic Response in E. coli Determined by High-Throughput Capillary Assay

Adler J (1966) Chemotaxis in bacteria. Science 153:708–716 Adler J (1973) A method for measuring chemotaxis and use of the method to determine optimum conditions for chemotaxis by Escherichia coli. J Gen Microbiol 74:77–91 Adler J, Dahl MM (1967) A method for measuring motility of bacteria and for comparing random and non-random motility. J Gen Microbiol 46:161 Alon U, Camarena L, Surette MG et al (1998) Response regulator output in bacterial chemotaxis. EMBO J 17:4238–4248 Alon U, Surette MG, Barkai N et al (1999) Robustness in bacterial chemotaxis. Nature 397:168–171 Amann E, Ochs B, Abel KJ (1988) Tightly regulated tac promoter vectors useful for the expression of unfused and fused proteins in Escherichia coli. Gene 69:301–315 Bainer R, Park H, Cluzel P (2003) A high-throughput capillary assay for bacterial chemotaxis. J Microbiol Methods 55:315–319 Barkai N, Leibler S (1997) Robustness in simple biochemical networks. Nature 387:913–917 Belas R, Erskine D, Flaherty D (1991) Proteus mirabilis mutants defective in swarmer cell differentiation and multicellular behavior. J Bacteriol 173:6279–6288 Bilwes AM, Alex LA, Crane BR et al (1999) Structure of CheA, a signal-transducing histidine kinase. Cell 96:131–141 Cluzel P, Surette M, Leibler S (2000) An ultrasensitive bacterial motor revealed by monitoring signaling proteins in single cells. Science 287:1652–1655 Emonet T, Cluzel P (2008) Relationship between cellular response and behavioral variability in bacterial chemotaxis. Proc Natl Acad Sci USA 105:3304–3309 Guzman LM, Belin D, Carson MJ et al (1995) Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter. J Bacteriol 177:4121–4130 Kollmann M, Lovdok L, Bartholome K et al (2005) Design principles of a bacterial signalling network. Nature 438:504–507 Li M, Hazelbauer GL (2004) Cellular stoichiometry of the components of the chemotaxis signaling complex. J Bacteriol 186:3687–3694 Lovdok L, Kollmann M, Sourjik V (2007) Co-expression of signaling proteins improves robustness of the bacterial chemotaxis pathway. J Biotechnol 129:173–180 Lutz R (1996) Untersuchungen zur Aktivierung und Repression von Sigma70 Promotoren in Escherichia coli. PhD Thesis, Heidelberg Lutz R, Bujard H (1997) Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements. Nucl Acids Res 25:1203–1210 Mesibov R, Adler J (1972) Chemotaxis toward amino-acids in Escherichia coli. J Bacteriol 112:315 Parkinson JS, Houts SE (1982) Isolation and behavior of Escherichia coli deletion mutants lacking chemotaxis functions. J Bacteriol 151:106–113 Paulsson J (2004) Summing up the noise in gene networks. Nature 427:415–418 Sherris D, Parkinson JS (1981) Posttranslational processing of methyl-accepting chemotaxis proteins in Escherichia coli. Proc Natl Acad Sci USA 78:6051–6055 Spiro PA, Parkinson JS, Othmer HG (1997) A model of excitation and adaptation in bacterial chemotaxis. Proc Natl Acad Sci USA 94:7263–7268 Stock JB, Lukat GS, Stock AM (1991) Bacterial chemotaxis and the molecular logic of intracellular signal transduction networks. Annu Rev Biophys Biophys Chem 20:109–136 Stock AM, Robinson VL, Goudreau PN (2000) Two-component signal transduction. Annu Rev Biochem 69:183–215 Toker AS, Macnab RM (1997) Distinct regions of bacterial flagellar switch protein FliM interact with FliG, FliN and CheY. J Mol Biol 273:623–634 Tso WW, Adler J (1974) Negative chemotaxis in Escherichia coli. J Bacteriol 118:560–576 Welch M, Oosawa K, Aizawa S et al (1993) Phosphorylation-dependent binding of a signal molecule to the flagellar switch of bacteria. Proc Natl Acad Sci USA 90:8787–8791 Welch M, Oosawa K, Aizawa SI et al (1994) Effects of phosphorylation, Mg2+, and conformation of the chemotaxis protein CheY on its binding to the flagellar switch protein FliM. Biochemistry 33:10470–10476