Filtering promiscuous compounds in early drug discovery: is it a good idea?

Drug Discovery Today - Tập 21 - Trang 868-872 - 2016
Mario R. Senger1, Carlos A.M. Fraga2, Rafael F. Dantas1, Floriano P. Silva1
1Laboratório de Bioquímica Experimental e Computacional de Fármacos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil
2Laboratório de Avaliação e Síntese de Substâncias Bioativas, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil

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