Ferroptosis, necroptosis, and pyroptosis in the occurrence and development of ovarian cancer

Li, 2022, HLF regulates ferroptosis, development and chemoresistance of triple-negative breast cancer by activating tumor cell-macrophage crosstalk, J Hematol Oncol, 15, 2, 10.1186/s13045-021-01223-x

Fillon, 2022, Opportunistic salpingectomy may reduce ovarian cancer risk, CA Cancer J Clin, 72, 10.3322/caac.21716

Torre, 2018, Ovarian cancer statistics, 2018, CA Cancer J Clin, 68, 10.3322/caac.21456

Gardner, 2021, Recurrent ovarian cancer - sculpting a promising future with surgery, N Engl J Med, 385, 10.1056/NEJMe2116353

Kosaka, 2021, What is the optimal treatment for vulnerable older women with ovarian cancer, JAMA Oncol, 7, 10.1001/jamaoncol.2021.4125

Kurian, 2022, Association of genetic testing results with mortality among women with breast cancer or ovarian cancer, J Natl Cancer Inst, 114, 10.1093/jnci/djab151

Kuroki, 2020, Treatment of epithelial ovarian cancer, BMJ, 371, m3773, 10.1136/bmj.m3773

Nameki, 2021, Transcription factors in epithelial ovarian cancer: histotype-specific drivers and novel therapeutic targets, Pharmacol Ther, 220, 107722, 10.1016/j.pharmthera.2020.107722

Wang, 2021, Emerging targeted drug delivery strategies toward ovarian cancer, Adv Drug Delivery Rev, 178, 113969, 10.1016/j.addr.2021.113969

Baert, 2021, The systemic treatment of recurrent ovarian cancer revisited, Ann Oncol, 32, 10.1016/j.annonc.2021.02.015

Ledermann, 2017, Front-line therapy of advanced ovarian cancer: new approaches, Ann Oncol, 28, viii46, 10.1093/annonc/mdx452

Chiappa, 2021, Overcoming PARPi resistance: Preclinical and clinical evidence in ovarian cancer, Drug Resist Update, 55, 100744, 10.1016/j.drup.2021.100744

Mirza, 2020, The forefront of ovarian cancer therapy: update on PARP inhibitors, Ann Oncol, 31, 10.1016/j.annonc.2020.06.004

Zeng, 2022, Targeting regulated cell death in tumor nanomedicines, Theranostics, 12, 10.7150/thno.67932

Tummers, 2022, The evolution of regulated cell death pathways in animals and their evasion by pathogens, Physiol Rev, 102, 10.1152/physrev.00002.2021

Zamzami, 1997, Mitochondrial implication in and programmed cell death: apoptosis and necrosis, J Bioenerg Biomembr, 29, 10.1023/A:1022694131572

Christgen, 2022, Programming inflammatory cell death for therapy, Pharmacol Ther, 232, 108010, 10.1016/j.pharmthera.2021.108010

Moujalled, 2021, Molecular mechanisms of cell death in neurological diseases, Cell Death Differ, 28, 10.1038/s41418-021-00814-y

Dionisio, 2021, Oxidative stress and regulated cell death in parkinson's disease, Ageing Res Rev, 67, 101263, 10.1016/j.arr.2021.101263

Koren, 2021, Modes of regulated cell death in cancer, Cancer Discov, 11, 10.1158/2159-8290.CD-20-0789

Bertheloot, 2021, Necroptosis, pyroptosis and apoptosis: an intricate game of cell death, Cell Mol Immunol, 18, 10.1038/s41423-020-00630-3

Verdonck, 2021, Viral manipulation of host cell necroptosis and pyroptosis, Trends Microbiol, 30, 10.1016/j.tim.2021.11.011

Roberts, 2022, The role of ubiquitination in apoptosis and necroptosis, Cell Death Differ, 29, 10.1038/s41418-021-00922-9

Yu, 2021, Pyroptosis: mechanisms and diseases, Signal Transduct Target Ther, 6, 128, 10.1038/s41392-021-00507-5

Wu, 2021, Cell death mediated by the pyroptosis pathway with the aid of nanotechnology: Prospects for cancer therapy, Angew Chem Int Ed Engl, 60, 10.1002/anie.202010281

Rana, 2022, GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis, Cell, 185, 283, 10.1016/j.cell.2021.12.024

Lu, 2021, Necroptosis signaling promotes inflammation, airway remodeling, and emphysema in chronic obstructive pulmonary disease, Am J Respir Crit Care Med, 204, 10.1164/rccm.202009-3442OC

Baik, 2021, ZBP1 not RIPK1 mediates tumor necroptosis in breast cancer, Nat Commun, 12, 2666, 10.1038/s41467-021-23004-3

Tan, 2021, Tumor suppressor DRD2 facilitates M1 macrophages and restricts NF-kappaB signaling to trigger pyroptosis in breast cancer, Theranostics, 11, 10.7150/thno.58322

Chen, 2022, Non-apoptotic cell death in ovarian cancer: Treatment, resistance and prognosis, BioMed Pharmacother, 150, 10.1016/j.biopha.2022.112929

Liu, 2022, Pyroptosis: A developing foreland of ovarian cancer treatment, Front Oncol, 12, 10.3389/fonc.2022.828303

Dixon, 2012, Ferroptosis: an iron-dependent form of nonapoptotic cell death, Cell, 149, 10.1016/j.cell.2012.03.042

Rodriguez, 2022, Persister cancer cells: Iron addiction and vulnerability to ferroptosis, Mol Cell, 82, 10.1016/j.molcel.2021.12.001

Yao, 2021, Emerging roles of energy metabolism in ferroptosis regulation of tumor cells, Adv Sci (Weinh), 8, 10.1002/advs.202100997

Ajoolabady, 2021, Ferritinophagy and ferroptosis in the management of metabolic diseases, Trends Endocrinol Metab, 32, 10.1016/j.tem.2021.04.010

Chen, 2021, Ferroptosis in infection, inflammation, and immunity, J Exp Med, 218, 10.1084/jem.20210518

Wang, 2022, Ferroptosis in parkinson's disease: glia-neuron crosstalk, Trends Mol Med, 28, 10.1016/j.molmed.2022.02.003

Chen, 2021, Organelle-specific regulation of ferroptosis, Cell Death Differ, 28, 10.1038/s41418-021-00859-z

Ebrahimi, 2022, Crosstalk between ferroptosis and the epithelial-mesenchymal transition: Implications for inflammation and cancer therapy, Cytokine Growth Factor Rev, 64, 33, 10.1016/j.cytogfr.2022.01.006

Yang, 2022, Role of pyroptosis and ferroptosis in the progression of atherosclerotic plaques, Front Cell Dev Biol, 10, 10.3389/fcell.2022.811196

Chen, 2022, The multifaceted role of ferroptosis in liver disease, Cell Death Differ, 29, 10.1038/s41418-022-00941-0

Lei, 2022, Targeting ferroptosis as a vulnerability in cancer, Nat Rev Cancer, 22, 10.1038/s41568-022-00459-0

Zhang, 2022, Ferroptosis in cancer therapy: a novel approach to reversing drug resistance, Mol Cancer, 21, 47, 10.1186/s12943-022-01530-y

Friedmann Angeli, 2022, CD8(+) T cells PUF(A)ing the flames of cancer ferroptotic cell death, Cancer Cell, 40, 10.1016/j.ccell.2022.03.003

Shui, 2021, Non-enzymatic lipid peroxidation initiated by photodynamic therapy drives a distinct ferroptosis-like cell death pathway, Redox Biol, 45, 102056, 10.1016/j.redox.2021.102056

Saito, 2021, Lipid peroxidation products as a mediator of toxicity and adaptive response - the regulatory role of selenoprotein and vitamin e, Arch Biochem Biophys, 703, 108840, 10.1016/j.abb.2021.108840

Foret, 2020, Connecting the "Dots": From free radical lipid autoxidation to cell pathology and disease, Chem Rev, 120, 10.1021/acs.chemrev.0c00761

Stoyanovsky, 2019, Iron catalysis of lipid peroxidation in ferroptosis: Regulated enzymatic or random free radical reaction, Free Radic Biol Med, 133, 10.1016/j.freeradbiomed.2018.09.008

Li, 2022, Pulmonary delivery of theranostic nanoclusters for lung cancer ferroptosis with enhanced Chemodynamic/Radiation synergistic therapy, Nano Lett, 22, 10.1021/acs.nanolett.1c03786

Lu, 2021, ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and iron, Acta Pharmacol Sin, 42, 10.1038/s41401-021-00700-w

Feng, 2022, NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury, Biochim Biophys Acta Mol Basis Dis, 1868, 166287, 10.1016/j.bbadis.2021.166287

Zhu, 2022, Mitochondrial aldehyde dehydrogenase (ALDH2) rescues cardiac contractile dysfunction in an APP/PS1 murine model of alzheimer's disease via inhibition of ACSL4-dependent ferroptosis, Acta Pharmacol Sin, 43, 39, 10.1038/s41401-021-00635-2

Alvarez, 2017, NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis, Nature, 551, 10.1038/nature24637

Wei, 2022, Exosome-derived lncRNA NEAT1 exacerbates sepsis-associated encephalopathy by promoting ferroptosis through regulating miR-9-5p/TFRC and GOT1 axis, Mol Neurobiol, 59, 10.1007/s12035-022-02738-1

Zhang, 2022, Curcumenol triggered ferroptosis in lung cancer cells via lncRNA H19/miR-19b-3p/FTH1 axis, Bioact Mater, 13, 23, 10.1016/j.bioactmat.2021.11.013

Shi, 2022, Cyclophosphamide induces the ferroptosis of tumor cells through heme oxygenase-1, Front Pharmacol, 13, 10.3389/fphar.2022.839464

Yang, 2022, A dual role of heme oxygenase-1 in tuberculosis, Front Immunol, 13, 10.3389/fimmu.2022.842858

Yang, 2022, Targeting ferroptosis suppresses osteocyte glucolipotoxicity and alleviates diabetic osteoporosis, Bone Res, 10, 26, 10.1038/s41413-022-00198-w

He, 2022, Ferroptosis and ferritinophagy in diabetes complications, Mol Metab, 60, 101470, 10.1016/j.molmet.2022.101470

Santana-Codina, 2021, The role of NCOA4-mediated ferritinophagy in ferroptosis, Adv Exp Med Biol, 1301, 41, 10.1007/978-3-030-62026-4_4

Liu, 2022, CEMIP promotes extracellular matrix-detached prostate cancer cells survival by inhibiting ferroptosis, Cancer Sci, 113, 10.1111/cas.15356

Wu, 2022, Genetic analysis of potential biomarkers and therapeutic targets in ferroptosis from coronary artery disease, J Cell Mol Med, 26, 10.1111/jcmm.17239

Zhou, 2022, Ferroptosis and its potential role in the nervous system diseases, J Inflammation Res, 15, 10.2147/JIR.S351799

Homma, 2021, Nitric oxide protects against ferroptosis by aborting the lipid peroxidation chain reaction, Nitric Oxide, 115, 34, 10.1016/j.niox.2021.07.003

Huang, 2022, Network pharmacology identifies therapeutic targets and the mechanisms of glutathione action in ferroptosis occurring in oral cancer, Front Pharmacol, 13, 10.3389/fphar.2022.851540

Li, 2022, Glycyrrhetinic acid nanoparticles combined with ferrotherapy for improved cancer immunotherapy, Acta Biomater, 144, 10.1016/j.actbio.2022.03.030

Pallotti, 2021, The roles of coenzyme q in disease: Direct and indirect involvement in cellular functions, Int J Mol Sci, 23, 10.3390/ijms23010128

Gan, 2021, Mitochondrial regulation of ferroptosis, J Cell Biol, 220, 10.1083/jcb.202105043

Yan, 2022, Necroptosis and tumor progression, Trends Cancer, 8, 10.1016/j.trecan.2021.09.003

Wang, 2021, Selenomethionine alleviates LPS-induced JNK/NLRP3 inflammasome-dependent necroptosis by modulating miR-15a and oxidative stress in chicken lungs, Metallomics, 13, 10.1093/mtomcs/mfab048

Wang, 2021, From pyroptosis, apoptosis and necroptosis to PANoptosis: A mechanistic compendium of programmed cell death pathways, Comput Struct Biotechnol J, 19, 10.1016/j.csbj.2021.07.038

Teh, 2022, Caspase-8 has dual roles in regulatory T cell homeostasis balancing immunity to infection and collateral inflammatory damage, Sci Immunol, 7, eabn8041, 10.1126/sciimmunol.abn8041

Li, 2022, Caspase-8 auto-cleavage regulates programmed cell death and collaborates with RIPK3/MLKL to prevent lymphopenia, Cell Death Differ, 10.1038/s41418-022-00938-9

Yin, 2022, TAB2 deficiency induces dilated cardiomyopathy by promoting RIPK1-dependent apoptosis and necroptosis, J Clin Invest, 132, 10.1172/JCI152297

Rosenbaum, 2010, Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model, J Neurosci Res, 88, 10.1002/jnr.22314

Zhang, 2021, The STING1 network regulates autophagy and cell death, Signal Transduct Target Ther, 6, 208, 10.1038/s41392-021-00613-4

Meng, 2021, The regulation of necroptosis by post-translational modifications, Cell Death Differ, 28, 10.1038/s41418-020-00722-7

Nicole, 2022, Necroptosis-driving genes RIPK1, RIPK3 and MLKL-p are associated with intratumoral CD3(+) and CD8(+) T cell density and predict prognosis in hepatocellular carcinoma, J Immunother Cancer, 10, 10.1136/jitc-2021-004031

Mohanty, 2022, RETRA induces necroptosis in cervical cancer cells through RIPK1, RIPK3, MLKL and increased ROS production, Eur J Pharmacol, 920, 174840, 10.1016/j.ejphar.2022.174840

Xu, 2021, Genetic regulation of RIPK1 and necroptosis, Annu Rev Genet, 55, 10.1146/annurev-genet-071719-022748

Peng, 2022, Pathogen hijacks programmed cell death signaling by arginine ADPR-deacylization of caspases, Mol Cell, 82, 10.1016/j.molcel.2022.03.010

Woznicki, 2021, TNF-alpha synergises with IFN-gamma to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells, Cell Death Dis, 12, 864, 10.1038/s41419-021-04151-3

Karlowitz, 2021, Surviving death: emerging concepts of RIPK3 and MLKL ubiquitination in the regulation of necroptosis, FEBS J, 10.1111/febs.16255

Sethi, 2022, Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL, Cell Death Differ, 10.1038/s41418-022-00965-6

Martens, 2021, MLKL in cancer: more than a necroptosis regulator, Cell Death Differ, 28, 10.1038/s41418-021-00785-0

Shlomovitz, 2021, Proteomic analysis of necroptotic extracellular vesicles, Cell Death Dis, 12, 1059, 10.1038/s41419-021-04317-z

Yu, 2021, Necroptosis: A novel pathway in neuroinflammation, Front Pharmacol, 12, 10.3389/fphar.2021.701564

Liu, 2022, Insights into N6-methyladenosine and programmed cell death in cancer, Mol Cancer, 21, 32, 10.1186/s12943-022-01508-w

Bauernfried, 2022, Human NLRP1: From the shadows to center stage, J Exp Med, 219, 10.1084/jem.20211405

Hou, 2021, Molecular mechanisms and functions of pyroptosis in inflammation and antitumor immunity, Mol Cell, 81, 10.1016/j.molcel.2021.09.003

Zychlinsky, 1992, Shigella flexneri induces apoptosis in infected macrophages, Nature, 358, 10.1038/358167a0

Cookson, 2001, Pro-inflammatory programmed cell death, Trends Microbiol, 9, 10.1016/S0966-842X(00)01936-3

Shi, 2014, Inflammatory caspases are innate immune receptors for intracellular LPS, Nature, 514, 10.1038/nature13683

Shi, 2015, Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death, Nature, 526, 10.1038/nature15514

Diaz-Garcia, 2022, Inflammasome activation: A keystone of proinflammatory response in obstructive sleep apnea, Am J Respir Crit Care Med, 205, 10.1164/rccm.202106-1445OC

Hsu, 2022, The lipid peroxidation product 4-hydroxynonenal inhibits NLRP3 inflammasome activation and macrophage pyroptosis, Cell Death Differ, 10.1038/s41418-022-00966-5

Xu, 2022, Ubiquitination of NLRP3 by gp78/Insig-1 restrains NLRP3 inflammasome activation, Cell Death Differ, 10.1038/s41418-022-00947-8

Ross, 2022, Inflammatory caspases: Toward a unified model for caspase activation by inflammasomes, Annu Rev Immunol, 40, 10.1146/annurev-immunol-101220-030653

Camilli, 2020, Beta-glucan-induced reprogramming of human macrophages inhibits NLRP3 inflammasome activation in cryopyrinopathies, J Clin Invest, 130, 10.1172/JCI134778

Lee, 2019, Influenza restriction factor MxA functions as inflammasome sensor in the respiratory epithelium, Sci Immunol, 4, 10.1126/sciimmunol.aau4643

Stancu, 2019, Aggregated tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded tau pathology in vivo, Acta Neuropathol, 137, 599, 10.1007/s00401-018-01957-y

Zhang, 2021, NLRC4 inflammasome-dependent cell death occurs by a complementary series of three death pathways and determines lethality in mice, Sci Adv, 7, 10.1126/sciadv.abi9471

Wu, 2021, The key role of NLRP3 and STING in APOL1-associated podocytopathy, J Clin Invest, 131, 10.1172/JCI136329

Ding, 2021, Biodegradable upconversion nanoparticles induce pyroptosis for cancer immunotherapy, Nano Lett, 21, 10.1021/acs.nanolett.1c02790

de Carvalho Ribeiro, 2022, Role of the inflammasome in liver disease, Annu Rev Pathol, 17, 10.1146/annurev-pathmechdis-032521-102529

Shao, 2021, Therapeutic potential of the target on NLRP3 inflammasome in multiple sclerosis, Pharmacol Ther, 227, 107880, 10.1016/j.pharmthera.2021.107880

Liu, 2020, HSPA12A attenuates lipopolysaccharide-induced liver injury through inhibiting caspase-11-mediated hepatocyte pyroptosis via PGC-1alpha-dependent acyloxyacyl hydrolase expression, Cell Death Differ, 27, 10.1038/s41418-020-0536-x

Lee, 2018, Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation, J Exp Med, 215, 10.1084/jem.20180589

Gao, 2022, TRIM21 regulates pyroptotic cell death by promoting gasdermin d oligomerization, Cell Death Differ, 29, 10.1038/s41418-021-00867-z

Petrovski, 2011, Phagocytosis of cells dying through autophagy induces inflammasome activation and IL-1beta release in human macrophages, Autophagy, 7, 10.4161/auto.7.3.14583

Moujalled, 2022, BH3 mimetic drugs cooperate with temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells, Cell Death Differ, 10.1038/s41418-022-00977-2

Li, 2022, Multienzyme-like reactivity cooperatively impairs glutathione peroxidase 4 and ferroptosis suppressor protein 1 pathways in triple-negative breast cancer for sensitized ferroptosis therapy, ACS Nano, 16, 10.1021/acsnano.1c08664

Chen, 2022, CRISPR screens uncover protective effect of PSTK as a regulator of chemotherapy-induced ferroptosis in hepatocellular carcinoma, Mol Cancer, 21, 11, 10.1186/s12943-021-01466-9

Bolik, 2022, Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis, J Exp Med, 219, 10.1084/jem.20201039

Tan, 2021, Somatic epigenetic silencing of RIPK3 inactivates necroptosis and contributes to chemoresistance in malignant mesothelioma, Clin Cancer Res, 27, 10.1158/1078-0432.CCR-18-3683

Xie, 2020, Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer, J Clin Invest, 130, 10.1172/JCI133264

Tang, 2020, MELK is an oncogenic kinase essential for metastasis, mitotic progression, and programmed death in lung carcinoma, Signal Transduct Target Ther, 5, 279, 10.1038/s41392-020-00288-3

Tan, 2020, HMGB1 released from GSDME-mediated pyroptotic epithelial cells participates in the tumorigenesis of colitis-associated colorectal cancer through the ERK1/2 pathway, J Hematol Oncol, 13, 149, 10.1186/s13045-020-00985-0

Zhang, 2022, CircNEIL3 mediates pyroptosis to influence lung adenocarcinoma radiotherapy by upregulating PIF1 through miR-1184 inhibition, Cell Death Dis, 13, 167, 10.1038/s41419-022-04561-x

Banoth, 2020, ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis), J Biol Chem, 295, 10.1074/jbc.RA120.015924

Shi, 2019, Bcl-2 regulates pyroptosis and necroptosis by targeting BH3-like domains in GSDMD and MLKL, Cell Death Discovery, 5, 151, 10.1038/s41420-019-0230-2

Fritsch, 2019, Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis, Nature, 575, 10.1038/s41586-019-1770-6

Zhou, 2018, Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis, Cell Res, 28, 10.1038/s41422-018-0090-y

Wang, 2020, Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload, Cell Death Dis, 11, 574, 10.1038/s41419-020-02777-3

Liu, 2021, Non-coding RNAs in necroptosis, pyroptosis and ferroptosis in cancer metastasis, Cell Death Discovery, 7, 210, 10.1038/s41420-021-00596-9

Li, 2021, Significance of glutathione peroxidase 4 and intracellular iron level in ovarian cancer cells-"utilization" of ferroptosis mechanism, Inflammation Res, 70, 10.1007/s00011-021-01495-6

Tesfay, 2019, Stearoyl-CoA desaturase 1 protects ovarian cancer cells from ferroptotic cell death, Cancer Res, 79, 10.1158/0008-5472.CAN-19-0369

Ma, 2021, Tumor suppressor miR-424-5p abrogates ferroptosis in ovarian cancer through targeting ACSL4, Neoplasma, 68, 10.4149/neo_2020_200707N705

Zhang, 2021, p53 promoted ferroptosis in ovarian cancer cells treated with human serum incubated-superparamagnetic iron oxides, Int J Nanomed, 16, 10.2147/IJN.S282489

Hong, 2021, PARP inhibition promotes ferroptosis via repressing SLC7A11 and synergizes with ferroptosis inducers in BRCA-proficient ovarian cancer, Redox Biol, 42, 101928, 10.1016/j.redox.2021.101928

Jin, 2022, SNAI2 promotes the development of ovarian cancer through regulating ferroptosis, Bioengineered, 13, 10.1080/21655979.2021.2024319

Cai, 2022, Long non-coding RNA ADAMTS9-AS1 attenuates ferroptosis by targeting microRNA-587/solute carrier family 7 member 11 axis in epithelial ovarian cancer, Bioengineered, 13, 10.1080/21655979.2022.2049470

Mao, 2022, Sodium molybdate inhibits the growth of ovarian cancer cells via inducing both ferroptosis and apoptosis, Free Radic Biol Med, 182, 79, 10.1016/j.freeradbiomed.2022.02.023

Yang, 2020, A TAZ-ANGPTL4-NOX2 axis regulates ferroptotic cell death and chemoresistance in epithelial ovarian cancer, Mol Cancer Res, 18, 79, 10.1158/1541-7786.MCR-19-0691

Chakraborty, 2015, Role of cystathionine beta synthase in lipid metabolism in ovarian cancer, Oncotarget, 6, 10.18632/oncotarget.5424

Wang, 2021, Frizzled-7 identifies platinum-tolerant ovarian cancer cells susceptible to ferroptosis, Cancer Res, 81, 10.1158/0008-5472.CAN-20-1488

Cheng, 2021, Erastin synergizes with cisplatin via ferroptosis to inhibit ovarian cancer growth in vitro and in vivo, J Obstet Gynaecol Res, 47, 10.1111/jog.14779

Li, 2022, GALNT14 regulates ferroptosis and apoptosis of ovarian cancer through the EGFR/mTOR pathway, Future Oncol, 18, 10.2217/fon-2021-0883

Chan, 2020, MAP30 protein from momordica charantia is therapeutic and has synergic activity with cisplatin against ovarian cancer in vivo by altering metabolism and inducing ferroptosis, Pharmacol Res, 161, 105157, 10.1016/j.phrs.2020.105157

Sun, 2021, Lidocaine promoted ferroptosis by targeting miR-382-5p /SLC7A11 axis in ovarian and breast cancer, Front Pharmacol, 12, 10.3389/fphar.2021.681223

Basuli, 2017, Iron addiction: a novel therapeutic target in ovarian cancer, Oncogene, 36, 10.1038/onc.2017.11

Quartuccio, 2015, Mutant p53 expression in fallopian tube epithelium drives cell migration, Int J Cancer, 137, 10.1002/ijc.29528

Liu, 2020, Activation of the reverse transsulfuration pathway through NRF2/CBS confers erastin-induced ferroptosis resistance, Br J Cancer, 122, 10.1038/s41416-019-0660-x

Verschoor, 2013, Ets-1 regulates intracellular glutathione levels: key target for resistant ovarian cancer, Mol Cancer, 12, 138, 10.1186/1476-4598-12-138

Santos, 2019, Targeting glutathione and cystathionine beta-synthase in ovarian cancer treatment by selenium-chrysin polyurea dendrimer nanoformulation, Nutrients, 11, 10.3390/11102523

Yang, 2021, Ferroptosis-related gene model to predict overall survival of ovarian carcinoma, J Oncol, 2021, 6687391, 10.1155/2021/6687391

Zhang, 2021, Comprehensive analysis identifies potential ferroptosis-associated mRNA therapeutic targets in ovarian cancer, Front Med (Lausanne), 8, 10.3389/fmed.2021.644053

Ye, 2021, A novel defined risk signature of the ferroptosis-related genes for predicting the prognosis of ovarian cancer, Front Mol Biosci, 8, 10.3389/fmolb.2021.645845

Yu, 2021, A novel ferroptosis related gene signature is associated with prognosis in patients with ovarian serous cystadenocarcinoma, Sci Rep, 11, 11486, 10.1038/s41598-021-90126-5

You, 2021, Ferroptosis-related gene signature promotes ovarian cancer by influencing immune infiltration and invasion, J Oncol, 2021, 9915312, 10.1155/2021/9915312

Li, 2021, Comprehensive analysis of the tumor microenvironment and ferroptosis-related genes predict prognosis with ovarian cancer, Front Genet, 12, 10.3389/fgene.2021.774400

Feng, 2022, Integrated clinical characteristics and omics analysis identifies a ferroptosis and iron-metabolism-related lncRNA signature for predicting prognosis and therapeutic responses in ovarian cancer, J Ovarian Res, 15, 10, 10.1186/s13048-022-00944-y

Wang, 2021, Integrated analysis of ferroptosis-related biomarker signatures to improve the diagnosis and prognosis prediction of ovarian cancer, Front Cell Dev Biol, 9, 10.3389/fcell.2021.807862

Peng, 2021, A ferroptosis-related lncRNA signature predicts prognosis in ovarian cancer patients, Transl Cancer Res, 10, 10.21037/tcr-21-1152

Zheng, 2021, Bioinformatic analyses of the ferroptosis-related lncRNAs signature for ovarian cancer, Front Mol Biosci, 8, 10.3389/fmolb.2021.735871

Hahne, 2015, Anti-tumour activity of phosphoinositide-3-kinase antagonist AEZS-126 in models of ovarian cancer, Arch Gynecol Obstet, 291, 10.1007/s00404-014-3389-z

McCabe, 2014, Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma, Cell Death Dis, 5, 10.1038/cddis.2014.448

Qiu, 2015, CD40 ligand induces RIP1-dependent, necroptosis-like cell death in low-grade serous but not serous borderline ovarian tumor cells, Cell Death Dis, 6, 10.1038/cddis.2015.229

Dey, 2016, Inhibition of BMI1 induces autophagy-mediated necroptosis, Autophagy, 12, 10.1080/15548627.2016.1147670

Hernandez, 2015, A dual role for Caspase8 and NF-kappaB interactions in regulating apoptosis and necroptosis of ovarian cancer, with correlation to patient survival, Cell Death Discov, 1, 15053, 10.1038/cddiscovery.2015.53

Wu, 2017, Progesterone prevents high-grade serous ovarian cancer by inducing necroptosis of p53-defective fallopian tube epithelial cells, Cell Rep, 18, 10.1016/j.celrep.2017.02.049

Zhang, 2018, Ceramide nanoliposomes as a MLKL-dependent, necroptosis-inducing, chemotherapeutic reagent in ovarian cancer, Mol Cancer Ther, 17, 10.1158/1535-7163.MCT-17-0173

Thibault, 2018, DEBIO 1143, an IAP inhibitor, reverses carboplatin resistance in ovarian cancer cells and triggers apoptotic or necroptotic cell death, Sci Rep, 8, 17862, 10.1038/s41598-018-35860-z

Chefetz, 2019, A pan-ALDH1A inhibitor induces necroptosis in ovarian cancer stem-like cells, Cell Rep, 26, 3061, 10.1016/j.celrep.2019.02.032

Chen, 2019, CuS-MnS2 nano-flowers for magnetic resonance imaging guided photothermal/photodynamic therapy of ovarian cancer through necroptosis, Nanoscale, 11, 10.1039/C9NR03114F

Liu, 2019, Berberine in combination with cisplatin induces necroptosis and apoptosis in ovarian cancer cells, Biol Res, 52, 37, 10.1186/s40659-019-0243-6

Zheng, 2020, RIP1 promotes proliferation through G2/M checkpoint progression and mediates cisplatin-induced apoptosis and necroptosis in human ovarian cancer cells, Acta Pharmacol Sin, 41, 10.1038/s41401-019-0340-7

Liang, 2020, Osthole inhibits ovarian carcinoma cells through LC3-mediated autophagy and GSDME-dependent pyroptosis except for apoptosis, Eur J Pharmacol, 874, 172990, 10.1016/j.ejphar.2020.172990

Qiao, 2019, Alpha-NETA induces pyroptosis of epithelial ovarian cancer cells through the GSDMD/caspase-4 pathway, FASEB J, 33, 10.1096/fj.201900483RR

Zhang, 2020, Nobiletin triggers reactive oxygen species-mediated pyroptosis through regulating autophagy in ovarian cancer cells, J Agric Food Chem, 68, 10.1021/acs.jafc.9b07908

Tan, 2021, LncRNA HOTTIP inhibits cell pyroptosis by targeting miR-148a-3p/AKT2 axis in ovarian cancer, Cell Biol Int, 45, 10.1002/cbin.11588

Ye, 2021, A novel defined pyroptosis-related gene signature for predicting the prognosis of ovarian cancer, Cell Death Discovery, 7, 71, 10.1038/s41420-021-00451-x

Berkel, 2021, Differential expression and copy number variation of gasdermin (GSDM) family members, pore-forming proteins in pyroptosis, in normal and malignant serous ovarian tissue, Inflammation, 44, 10.1007/s10753-021-01493-0

Zhou, 2021, Genomic, immunological, and clinical characterization of pyroptosis in ovarian cancer, J Inflammation Res, 14, 10.2147/JIR.S344554

Zhang, 2021, Role of a pyroptosis-related lncRNA signature in risk stratification and immunotherapy of ovarian cancer, Front Med (Lausanne), 8, 10.3389/fmed.2021.793515

Cao, 2022, Derivation, comprehensive analysis, and assay validation of a pyroptosis-related lncRNA prognostic signature in patients with ovarian cancer, Front Oncol, 12, 10.3389/fonc.2022.780950

Cai, 2022, Pyroptosis-related inflammasome pathway: A new therapeutic target for diabetic cardiomyopathy, Front Pharmacol, 13, 10.3389/fphar.2022.842313

Qi, 2022, Application of regulatory cell death in cancer: Based on targeted therapy and immunotherapy, Front Immunol, 13, 10.3389/fimmu.2022.837293

Zhao, 2021, Apoptosis, autophagy, NETosis, necroptosis, and pyroptosis mediated programmed cell death as targets for innovative therapy in rheumatoid arthritis, Front Immunol, 12, 10.3389/fimmu.2021.809806

Park, 2022, Role of mass spectrometry-based serum proteomics signatures in predicting clinical outcomes and toxicity in patients with cancer treated with immunotherapy, J Immunother Cancer, 10, 10.1136/jitc-2021-003566

Huang, 2022, Nobiletin as an inducer of programmed cell death in cancer: a review, Apoptosis, 27, 10.1007/s10495-022-01721-4

Zhang, 2022, Emerging photodynamic nanotherapeutics for inducing immunogenic cell death and potentiating cancer immunotherapy, Biomaterials, 282, 121433, 10.1016/j.biomaterials.2022.121433

Zuo, 2022, Ferroptosis in cancer progression: Role of noncoding RNAs, Int J Biol Sci, 18, 10.7150/ijbs.66917

Yang, 2021, Targeting cell death: Pyroptosis, ferroptosis, apoptosis and necroptosis in osteoarthritis, Front Cell Dev Biol, 9, 10.3389/fcell.2021.789948

Xu, 2022, Regulation of inflammatory cell death by phosphorylation, Front Immunol, 13, 10.3389/fimmu.2022.851169

Zhuang, 2021, A glimpse of programmed cell death among bacteria, animals, and plants, Front Cell Dev Biol, 9, 10.3389/fcell.2021.790117

Liu, 2022, Molecular insights into the biochemical functions and signalling mechanisms of plant NLRs, Mol Plant Pathol, 23, 10.1111/mpp.13195

Ryan, 2022, Immunothrombosis and the molecular control of tissue factor by pyroptosis: prospects for new anticoagulants, Biochem J, 479, 10.1042/BCJ20210522