Features of Intestinal Disease Associated With COVID‐Related Multisystem Inflammatory Syndrome in Children

Journal of Pediatric Gastroenterology and Nutrition - Tập 72 Số 3 - Trang 384-387 - 2021
Benjamin Sahn1, Ogechukwu Eze2, Morris Edelman3, Christina E. Chougar4, Rebecca Thomas2, Charles L. Schleien5, Toba Weinstein6
1Division of Gastroenterology, Liver Disease, and Nutrition, Department of Pediatrics
2Department of Pathology and Laboratory Medicine
3Division of Pediatric Pathology Zucker School of Medicine at Hofstra/Northwell Steven & Alexandra Cohen Children's Medical Center Northwell Health
4Department of Radiology, Long Island Jewish Medical Center/Northwell Health
5Philip Lanzkowsky Chair of Pediatrics
6Division of Gastroenterology, Liver Disease, and Nutrition, Department of Pediatrics, Zucker School of Medicine at Hofstra/Northwell, Steven & Alexandra Cohen Children's Medical Center, Northwell Health.

Tóm tắt

ABSTRACTMultisystem inflammatory syndrome in children (MIS‐C) is a recently identified syndrome that appears to be temporally associated with novel coronavirus 2019 infection. MIS‐C presents with fever and evidence of systemic inflammation, which can manifest as cardiovascular, pulmonary, neurologic, and gastrointestinal (GI) system dysfunction. Presenting GI symptoms are seen in the majority, including abdominal pain, diarrhea, and vomiting. Any segment of the GI tract may be affected; however, inflammation in the ileum and colon predominates. Progressive bowel wall thickening can lead to luminal narrowing and obstruction. Most will have resolution of intestinal inflammation with medical therapies; however, in rare instances, surgical resection may be required.

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