Fasting blood glucose at admission is an independent predictor for 28-day mortality in patients with COVID-19 without previous diagnosis of diabetes: a multi-centre retrospective study

Springer Science and Business Media LLC - Tập 63 Số 10 - Trang 2102-2111 - 2020
Sufei Wang1, Pei Ma1, Shujing Zhang1, Siwei Song1, Zhihui Wang2, Yanling Ma1, Jing Xu1, Feng Wu1, Limin Duan1, Zhengrong Yin1, Huilin Luo3, Nian Xiong4, Man Xu5, Tianshu Zeng6, Yang Jin1
1Department of Respiratory and Critical Care Medicine, NHC Key Laboratory of Pulmonary Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, Hubei, China
2Department of Scientific Research, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
3Department of Anesthesia, Wuhan Red Cross Hospital, Wuhan, Hubei, China
4Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
5Key Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
6Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, Hubei, China

Tóm tắt

Từ khóa


Tài liệu tham khảo

WHO (2020) Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19) Available from www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-covid-19-final-report.pdf. Accessed 30 Mar 2020

WHO (2020) Rolling updates on coronavirus disease (COVID-19). Available from www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen. Accessed 11 Apr 2020

WHO (2020) Coronavirus disease (COVID-19) pandemic. Available from www.who.int/emergencies/diseases/novel-coronavirus-2019. Accessed 7 June 2020

Bragg F, Holmes MV, Iona A et al (2017) Association between diabetes and cause-specific mortality in rural and urban areas of China. JAMA 317(3):280–289. https://doi.org/10.1001/jama.2016.19720

Gregg EW, Cheng YJ, Srinivasan M et al (2018) Trends in cause-specific mortality among adults with and without diagnosed diabetes in the USA: an epidemiological analysis of linked national survey and vital statistics data. Lancet 391(10138):2430–2440. https://doi.org/10.1016/s0140-6736(18)30314-3

Pearson-Stuttard J, Blundell S, Harris T, Cook DG, Critchley J (2016) Diabetes and infection: assessing the association with glycaemic control in population-based studies. Lancet Diabetes Endocrinol 4(2):148–158. https://doi.org/10.1016/s2213-8587(15)00379-4

Rao Kondapally Seshasai S, Kaptoge S, Thompson A et al (2011) Diabetes mellitus, fasting glucose, and risk of cause-specific death. N Engl J Med 364(9):829–841. https://doi.org/10.1056/NEJMoa1008862

Ehrlich SF, Quesenberry CP Jr, Van Den Eeden SK, Shan J, Ferrara A (2010) Patients diagnosed with diabetes are at increased risk for asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, and pneumonia but not lung cancer. Diabetes Care 33(1):55–60. https://doi.org/10.2337/dc09-0880

Lepper PM, Ott S, Nuesch E et al (2012) Serum glucose levels for predicting death in patients admitted to hospital for community acquired pneumonia: prospective cohort study. BMJ 344:e3397. https://doi.org/10.1136/bmj.e3397

McAlister FA, Majumdar SR, Blitz S, Rowe BH, Romney J, Marrie TJ (2005) The relation between hyperglycemia and outcomes in 2,471 patients admitted to the hospital with community-acquired pneumonia. Diabetes Care 28(4):810–815. https://doi.org/10.2337/diacare.28.4.810

Yang JK, Feng Y, Yuan MY et al (2006) Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS. Diabet Med 23(6):623–628. https://doi.org/10.1111/j.1464-5491.2006.01861.x

Alanazi KH, Abedi GR, Midgley CM et al (2020) Diabetes mellitus, hypertension, and death among 32 patients with MERS-CoV infection, Saudi Arabia. Emerg Infect Dis 26(1):166–168. https://doi.org/10.3201/eid2601.190952

Bode B, Garrett V, Messler J et al (2020) Glycemic characteristics and clinical outcomes of COVID-19 patients hospitalized in the United States. J Diabetes Sci Technol:193229682092446. https://doi.org/10.1177/1932296820924469

Zhu L, She ZG, Cheng X et al (2020) Association of blood glucose control and outcomes in patients with COVID-19 and pre-existing type 2 diabetes. Cell Metab 31(6):1068–1077.e3. https://doi.org/10.1016/j.cmet.2020.04.021

WHO (2020) Laboratory testing for coronavirus disease 2019 (COVID-19) in suspected human cases. Available from www.who.int/publications-detail/laboratory-testing-for-2019-novel-coronavirus-in-suspected-human-cases-20200117. Accessed 31 Mar 2020

National Health Commission of the People’s Republic of China (2020) Diagnosis and treatment plan of coronavirus disease 2019 (COVID-19) (trial version 6) Available from www.nhc.gov.cn/yzygj/s7653p/202002/8334a8326dd94d329df351d7da8aefc2/files/b218cfeb1bc54639af227f922bf6b817.pdf. Accessed 31 Mar 2020 [document in Chinese]

WHO (2020) Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected: interim guidance, 13 March 2020. Available from https://apps.who.int/iris/handle/10665/331446. Accessed 30 Mar 2020

Huang C, Wang Y, Li X et al (2020) Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 395(10223):497–506. https://doi.org/10.1016/s0140-6736(20)30183-5

Khwaja A (2012) KDIGO clinical practice guidelines for acute kidney injury. Nephron Clin Pract 120(4):c179–c184. https://doi.org/10.1159/000339789

Schneider GT, Maier SAN (2020) Cerebrovascular accident. In: Weissbrod PA, Francis DO (eds) Neurologic and neurodegenerative diseases of the larynx. Springer, Cham, pp 215–228. https://doi.org/10.1007/978-3-030-28852-5_18

Zhou F, Yu T, Du R et al (2020) Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 395(10229):1054–1062. https://doi.org/10.1016/s0140-6736(20)30566-3

Ewig S, Bauer T, Richter K et al (2013) Prediction of in-hospital death from community-acquired pneumonia by varying CRB-age groups. Eur Respir J 41(4):917–922. https://doi.org/10.1183/09031936.00065212

Ewig S, Birkner N, Strauss R et al (2009) New perspectives on community-acquired pneumonia in 388 406 patients. Results from a nationwide mandatory performance measurement programme in healthcare quality. Thorax 64(12):1062–1069. https://doi.org/10.1136/thx.2008.109785

Shi H, Han X, Jiang N et al (2020) Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study. Lancet Infect Dis 20(4):425–434. https://doi.org/10.1016/s1473-3099(20)30086-4

Yang X, Yu Y, Xu J et al (2020) Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med 8(5):475–481. https://doi.org/10.1016/s2213-2600(20)30079-5

Wu C, Chen X, Cai Y et al (2020) Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China. JAMA Intern Med https://doi.org/10.1001/jamainternmed.2020.0994

Bauer TT, Ewig S, Marre R, Suttorp N, Welte T (2006) CRB-65 predicts death from community-acquired pneumonia. J Intern Med 260(1):93–101. https://doi.org/10.1111/j.1365-2796.2006.01657.x

Bar-Or D, Rael LT, Madayag RM et al (2019) Stress hyperglycemia in critically ill patients: insight into possible molecular pathways. Front Med (Lausanne) 6:54. https://doi.org/10.3389/fmed.2019.00054

Whitcomb BW, Pradhan EK, Pittas AG, Roghmann MC, Perencevich EN (2005) Impact of admission hyperglycemia on hospital mortality in various intensive care unit populations. Crit Care Med 33(12):2772–2777. https://doi.org/10.1097/01.ccm.0000189741.44071.25

Burcelin R, Amar J (2015) Diabetes: antibiotics or prodiabetics? Nat Rev Endocrinol 11(7):385–386. https://doi.org/10.1038/nrendo.2015.75

Johns EC, Reynolds RM (2019) Topical glucocorticoids and risk of type 2 diabetes mellitus. Nat Rev Endocrinol 15(7):379–380. https://doi.org/10.1038/s41574-019-0212-8

Van den Berghe G, Wouters P, Weekers F et al (2001) Intensive insulin therapy in critically ill patients. N Engl J Med 345(19):1359–1367. https://doi.org/10.1056/NEJMoa011300

Van den Berghe G, Wilmer A, Hermans G et al (2006) Intensive insulin therapy in the medical ICU. N Engl J Med 354(5):449–461. https://doi.org/10.1056/NEJMoa052521

Finfer S, Chittock DR, Su SY et al (2009) Intensive versus conventional glucose control in critically ill patients. N Engl J Med 360(13):1283–1297. https://doi.org/10.1056/NEJMoa0810625

Stapleton RD, Heyland DK (2020) UpToDate: glycemic control and intensive insulin therapy in critical illness. Available from www.uptodate.com/contents/glycemic-control-and-intensive-insulin-therapy-in-critical-illness. Accessed 30 Mar 2020