False leukemia–lymphoma cell lines: an update on over 500 cell lines
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Drexler HG (ed.). The Leukemia–Lymphoma Cell Line FactsBook, Academic Press: San Diego 2000.
Drexler HG, Dirks WG, MacLeod RAF . False human hematopoietic cell lines: cross-contaminations and misinterpretations. Leukemia 1999; 13: 1601–1607.
Markovic O, Markovic N . Cell cross-contamination in cell cultures: the silent and neglected danger. In Vitro Cell Dev Biol 1998; 34: 1–8.
Masters JR . HeLa cells 50 years on: the good, the bad and the ugly. Nature Rev Cancer 2002; 2: 315–319.
Drexler HG, Uphoff CC, Dirks WG, MacLeod RAF . Mix-ups and mycoplasma: the enemies within. Leukemia Res 2002; 26: 329–333.
Drexler HG, Häne B, Hu ZB, Uphoff CC . HeLa cross-contamination of a leukemia cell line. Leukemia 1993; 7: 2077–2078.
Gignac SM, Steube K, Schleithoff L, Janssen JWG, MacLeod RAF, Quentmeier H, Drexler HG . Multiparameter approach in the identification of cross-contaminated leukemia cell lines. Leuk Lymphoma 1993; 10: 359–368.
Häne B, Tümmler M, Jäger K, Schleithoff L, Janssen JWG, Drexler HG . Differences in DNA fingerprints of continuous leukemia–lymphoma cell lines from different sources. Leukemia 1992; 6: 1129–1133.
Jeffreys AJ, Wilson V, Thein SL . Hypervariable ‘minisatellite’ regions in human DNA. Nature 1985; 314: 67–73.
Zischler H, Nanda I, Schäfer R, Schmid M, Epplen JT . Digoxigenated oligonucleotide probes specific for simple repeats in DNA fingerprinting and hybridization in situ. Hum Genet 1989; 82: 227–233.
Gilbert DA, Reid YA, Gail MA, Pee D, White C, Hay RJ, O’Brien SJ . Application of DNA fingerprints for cell-line individualization. Am J Hum Genet 1990; 47: 499–514.
Jeffreys AJ, Wilson V, Thein SL . Individual-specific ‘fingerprints’ of human DNA. Nature 1985; 316: 76–79.
Dirks W, MacLeod RAF, Jäger K, Milch H, Drexler HG . First searchable database for DNA profiles of human cell lines: sequential use of fingerprint techniques for authentication. Cell Mol Biol 1999; 45: 841–853.
Dirks WG, Drexler HG . Authentication of Cancer Cell Lines by DNA Fingerprinting. In: Langdon S (ed.) Cancer Cell Culture – Methods and Protocols, Humana Press: Totowa, NJ (in press)
Dirks WG, MacLeod RAF, Drexler HG . ECV304 (endothelial) is really T24 (bladder carcinoma): Cell line cross-contamination at source. In Vitro Cell Dev Biol 1999; 35: 558–559.
MacLeod RAF, Dirks WG, Reid YA, Hay RJ, Drexler HG . Identity of original and late-passage Dami megakaryocytes with HEL erythroleukemia cells shown by combined cytogenetics and DNA fingerprinting. Leukemia 1997; 11: 2032–2038.
MacLeod RAF, Drexler HG . Cytogenetic characterization of Tumor Cell Lines. In: Langdon S (ed.) Cancer Cell Culture – Methods and Protocols, Humana Press: Totowa, NJ (in press)
ISCN. Mitelman F (ed). An International System for Human Chromosome Nomenclature, S Karger: Basel 1995.
MacLeod RAF, Drexler HG . Authentication and Characterization. In: Masters JRW, Palsson BO (eds)Human Cell Culture, Vol. III – Cancer Cell Lines Part 3: Leukemias and Lymphomas, Kluwer Academic Pub: Dordrecht 2000. pp 371–397.
MacLeod RAF, Dirks WG, Kaufmann M, Matsuo Y, Milch H, Drexler HG . Widespread intraspecies cross-contamination of human tumor cell line arising at source. Int J Cancer 1999; 83: 555–563.
MacLeod RAF, Dirks WG, Drexler HG . Persistent use of misidentified cell lines and its prevention. Genes Chromosomes Cancer 2002; 33: 103–105.
Findley HW Jr, Cooper MD, Kim TH, Alvarado C, Ragab AH . Two new acute lymphoblastic leukemia cell lines with early B-cell phenotype. Blood 1982; 60: 1305–1309.
Rosenfeld C, Goutner A, Choquet C, Venuat AM, Kayibanda B, Pico JL . Phenotypic characterisation of a unique non-T, non-B acute lymphoblastic leukaemia cell line. Nature 1977; 267: 841–843.
Zhang LQ, Downie PA, Goodell WR, McCabe NR, LeBeau MM, Morgan R, Sklar J, Raimondi SC, Miley D, Goldberg A, Lu MM, Montag A, Smith SD . Establishment of cell lines from B-cell precursor acute lymphoblastic leukemia. Leukemia 1993; 7: 1865–1874.
Gazitt Y, HE YJ, Shults K, Stelzer GT, Cohen RJ . Isolation and characterization of an early T-helper/inducer cell line with a unique pattern of surface phenotype, constitutive cytokine secretion and myc oncogene expression. Leukemia 1993; 7: 2034–2044.
Foley GE, Lazarus H, Farber S, Uzman BG, Boone BA, McCarthy RE . Continuous culture of human lymphoblasts from peripheral blood of a child with acute leukemia. Cancer 1965; 18: 522–529.
Galili N, Galili U, Ravid Z, Schlesinger M, Goldblum N . Induction of differentiation with phorbol ester in a human T cell line (Be13) expressing both prothymocyte and thymocyte characteristics. Human Lymph Diff 1981; 1: 123–130.
Ravid Z, Goldblum N, Zaizov R, Schlesinger M, Kertes T, Minowada J, Verbi W, Greaves M . Establishment and characterization of a new leukaemic T-cell line (Peer) with an unusual phenotype. Int J Cancer 1980; 25: 705–710.
Hurwitz R, Hozier J, LeBien T, Minowada J, Gajl-Peczalska K, Kubonishi I, Kersey J . Characterization of a leukemic cell line of the pre-B phenotype. Int J Cancer 1979; 23: 174–180.
Wörmann B, Anderson JM, Liberty JA, Gajl-Peczalska K, Brunning RD, Silberman TL, Arthur DC, LeBien TW . Establishment of a leukemic cell model for studying human pre-B to B cell differentiation. J Immunol 1989; 142: 110–117.
Jones DB, Scott CS, Wright DH, Stein H, Beverley PCL, Payne SV, Crawford DH . Phenotypic analysis of an established cell line derived from a patient with Hodgkin’s disease (HD). Hematol Oncol 1985; 3: 133–145.
Greenberg SM, Rosenthal DS, Greeley TA, Tantravahi R, Handin RI . Characterization of a new megakaryocytic cell line: The Dami cell. Blood 1988; 72: 1968–1977.
Kávai M, Adány R, Pásti G, Surányi P, Szücs G, Muszbek L, Boján F, Szegedi G . Marker profile, enzyme activity, and function of a human myelomonocytic leukemia cell line. Cell Immunol 1992; 139: 531–540.
Lozzio CB, Lozzio BB . Cytotoxicity of a factor isolated from human spleen. J Natl Cancer Inst 1973; 50: 535–538.
Faguet GB, Satya-Prakash KL, Agee JF . Cytochemical, cytogenetic, immunophenotypic and tumorigenic characterization of two hairy cell lines. Blood 1988; 71: 422–429.
Zhou M, Zaki SR, Ragab AH, Findley HW . Characterization of a myeloperoxidase mRNA(+) acute lymphoblastic leukemia cell line (EU-1/ALL) established from a child with an apparent case of ALL. Leukemia 1994; 8: 659–663.
Zhou M, Gu L, James CD, He J, Yeager AM, Smith SD, Findley HW . Homozygous deletions of the CDKN2 (MTS1/p16ink4) gene in cell lines established from children with acute lymphoblastic leukemia. Leukemia 1995; 9: 1159–1161.
Wagner HJ, Klintworth F, Jabs W, Lange K, Schlegelberger B, Harder L, Feller AC, Bucsky P . Characterization of the novel, pediatric Hodgkin disease-derived cell line HKB-1. Med Ped Oncol 1998; 31: 138–143.
Morikawa S, Tatsumi E, Baba M, Harada T, Yasuhira K . Two E-rosette-forming lymphoid cell lines. Int J Cancer 1978; 21: 166–170.
Drexler HG, MacLeod RAF, Dirks WG . Cross-contamination: HS-Sultan is not a myeloma but a Burkitt lymphoma cell line. Blood 2001; 98: 3495–3496.
Kohn G, Mellman WJ, Moorhead PS, Loftus J, Henle G . Involvement of C group chromosomes in five Burkitt lymphoma cell lines. J Natl Cancer Inst 1967; 38: 209–222.
Osgood EE, Brooke JH . Continuous tissue culture of leukocytes from human leukemic bloods by application of ‘gradient’ principles. Blood 1955; 10: 1010–1022.
Ohta M, Furukawa Y, Ide C, Akiyama N, Utakoji T, Miura Y, Saito M . Establishment and characterization of four human monocytoid leukemia cell lines (JOSK-I, -S, -M and -K) with capabilities of monocyte–macrophage lineage differentiation and constitutive production of interleukin 1. Cancer Res 1986; 46: 3067–3074.
Sundström C, Nilsson K . Establishment and characterization of a human histiocytic lymphoma cell line (U-937). Int J Cancer 1976; 17: 565–577.
Kamamoto T, Okuno T, Sakoda H, Taniguchi Y, Kita K, Yoshida Y, Uchino H . Establishment of two Ph1 chromosome-positive cell lines, KPB-M8 and KPB-M15. Jpn J Clin Oncol 1986; 16: 107–115.
Ohkubo T, Kamamoto T, Kita K, Hiraoka A, Yoshida Y, Uchino H . A novel Ph1 chromosome positive cell line established from a patient with chronic myelogenous leukemia in blastic crisis. Leukemia Res 1985; 9: 921–926.
Inglés-Esteve J, Aventin A, Azqueta C, Kádár E, Bothner KM, Amill B, Limón A, García López J . A new human cell line with pre-B cell phenotype and t(5;12). Leukemia 1997; 11: 1040–1044.
Banerjee R, Bekesi JG, Tarcsafalvi A, Sperber K, Deak G, Choi HSH, Paronetto F, Holland JF, Acs G . Productive nonlytic human immunodeficiency virus type 1 replication in a newly established human leukemia cell line. Proc Natl Acad Sci USA 1992; 89: 9996–10000.
Schneider U, Schwenk HU, Bornkamm G . Characterization of EBV-genome negative ‘Null’ and ‘T’ cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non- Hodgkin lymphoma. Int J Cancer 1977; 19: 621–626.
Matsuo Y, Tomiyasu T, Shirakawa F, Yamashita U, Sagawa K, Yokoyama M, Minowada J . Establishment and characterization of a clonal human T-cell line, MKB-1 derived from a patient with acute myeloblastic leukemia. Human Cell 1989; 2: 423–429.
Drexler HG, Minowada J . Morphological, immunophenotypical and isoenzymatic profiles of human leukemia cells and derived T-cell lines. Hematol Oncol 1989; 7: 115–125.
Chen PM, Chiu CF, Chiou TJ, Maeda S, Chiang H, Tzeng CH, Sugiyama T, Chiang BN . Establishment and characterization of a human monocytoid leukemia cell line, CTV-1. Gann 1984; 75: 660–664.
Sahraoui Y, Perraki M, Theodoropoulou M, Allouche M, Tsapis A, Ammar A, Clemenceau C, Bokogiorgou S, Yacci T, Katrinakis G, Jasmin C, Georgoulias V . Autocrine IL-2-dependent growth of a newly established CD3+, CD16-, CD56+, CD57+, JH-, TCRβ-, TCRγ- leukemia cell line (NOI-90). Leukemia 1997; 11: 245–252.
Zheng A, Castren K, Saily M, Savolainen ER, Koistinen P, Vahakangas K . p53 status of newly established acute myeloid leukaemia cell lines. Br J Cancer 1999; 79: 407–415.
Wang C, Curtis JE, Minden MD, McCulloch EA . Expression of a retinoic acid receptor gene in myeloid leukemia cells. Leukemia 1989; 3: 264–269.
Pirruccello SJ, Lang MS, Sanger WG . PBEI: A pre-B acute lymphoblastic leukemia cell line derived from long term bone marrow culture. Blood 1991; 78: 39a.
Tucker KA, Lilly MB, Heck L Jr & Rado TA . Characterization of a new human diploid myeloid leukemia cell line (PLB-985) with granulocytic and monocytic differentiating capacity. Blood 1987; 70: 372–378.
Collins SJ, Gallo RC, Gallagher RE . Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture. Nature 1977; 270: 347–349.
Mallet MK, Mane SM, Meltzer SJ, Needleman SW . C-myc amplification coexistent with activating N-ras point mutation in the biphenotypic leukemic cell line RED-3. Leukemia 1989; 3: 511–515.
Hirata J, Sato H, Takahira H, Shiokawa S, Endo T, Nishimura J, Katsuno M, Masuda S, Sasaki R, Fukumaki Y, Nawata H, Okano H . A novel CD10-positive erythroid cell line, RM10, established from a patient with chronic myelogenous leukemia. Leukemia 1990; 4: 365–372.
Kamesaki H, Michaud GY, Irving SG, Suwabe N, Kamesaki S, Okuma M, Cossman J . TPA-induced arrest of erythroid differentiation is coupled with downregulation of GATA-1 and upregulation of GATA-2 in an erythroid cell line SAM-1. Blood 1996; 87: 999–1005.
Komiyama A, Kawai H, Miyagawa Y, Akabane T . Childhood lymphoblastic leukemia with natural killer activity: Establishment of the leukemia cell lines retaining the activity. Blood 1982; 60: 1429–1436.
Klingemann HG, Gong HJ, Maki G, Horsman DE, Dalal BI, Phillips GL . Establishment and characterization of a human leukemic cell line (SR-91) with features suggestive of early progenitor cell origin. Leuk Lymphoma 1994; 12: 463–470.
Lange B, Valtieri M, Santoli D, Caracciolo D, Mavilio F, Gemperlein I, Griffin C, Emanuel B, Finan J, Nowell P, Rovera G . Growth factor requirements of childhood acute leukemia: Establishment of GM-CSF-dependent cell lines. Blood 1987; 70: 192–199.
Rush J, Heinonen K, Mrozek K, Wolf BJ, Abdel-Rahman M, Szymanska J, Peltomaki P, Kapadia F, Bloomfield CD, Caligiuri MA, Plass C . Comprehensive cytogenetic and molecular genetic characterization of the TI–1 acute myeloid leukemia cell line reveals cross-contamination with K–562 cell line. Blood 2002; 99: 1874–1876.
Taoka T, Tasaka T, Tanaka T, Irino S, Norman AW . Characterization, growth, and differentiation of a human myeloid leukemia cell line, TI-1 cell. Blood 1992; 80: 46–52.
Juneja HS, Rajaraman S, Ramsey KM, Elder FFB . Role of bone marrow stromal cells in the establishment of a transformed lymphoblastic B-cell line from a normal human subject. Leukemia Res 1986; 10: 1209–1219.
Al-Katib A, Abubakr Y, Mohamed A, Maki A, Diuric Z, Mohammad R . Multiple mechanisms of drug resistance in anaplastic large cell lymphoma. Blood 1994; 84: 638a.
Drexler HG, Quentmeier H, Dirks WG, Uphoff CC, MacLeod RAF . DNA profiling and cytogenetic analysis of cell line WSU-CLL reveal cross-contamination with cell line REH (pre B-ALL). Leukemia 2002; 16: 1868–1870.
Mohammad RM, Mohamed AN, Hamdan MY, Vo T, Chen B, Katato K, Abubakr YA, Dugan MC, Al-Katib A . Establishment of a human B-CLL xenograft model: utility as a preclinical therapeutic model. Leukemia 1996; 10: 130–137.
Hamamoto Y, Nagai K, Muto M, Nakamura K, Yasui H, Asagami C . Establishment and characterization of a novel human cell line exhibiting both immunophenotypic markers of monocyte/macrophage and natural killer cell lineage from peripheral blood of a patient with atopic dermatitis. Exp Dermatol 1997; 6: 49–53.
Hamamoto Y, Nagai K, Muto M, Furumoto H, Mogami S, Asagami C . Establishment and characterization of a novel human promonocytic cell line from peripheral blood of a patient with psoriasis. Arch Dermatol Res 1996; 288: 225–229.
Yamaguchi Y, Nishio H, Kasahara T, Ackerman SJ, Koyanagi J, Suda T . Models of lineage switching in hematopoietic development: a new myeloid-committed eosinophil cell line (YJ) demonstrates trilineage potential. Leukemia 1998; 12: 1430–1439.
Menezes J, Leibold W, Klein G, Clements G . Establishment and characterization of an Epstein–Barr virus (EBV)-negative lymphoblastoid B cell line (BJA-B) from an exceptional, EBV-genome-negative African Burkitt’s lymphoma. Biomedicine 1975; 22: 276–284.
Cheng T, Erickson-Miller CL, Li C, Cardier J, Wang Y, Dempsey J, Mogle M, Barbera E, Murphy MJ Jr & Dai W . HIMeg-1, a cell line derived from a CML patient, is capable of monocytic and megakaryocytic differentiation. Leukemia 1995; 9: 1257–1263.
Abo J, Inokuchi K, Dan K, Nomura T . p53 and N-ras mutations in two new leukemia cell lines established from a patient with multilineage CD7-positive acute leukemia. Blood 1993; 82: 2829–2836.
Karpas A, Hayhoe FG, Greenberger JS, Barker CR, Cawley JC, Lowenthal RM, Moloney WC . The establishment and cytological, cytochemical and immunological characterisation of human haemic cell lines: evidence for heterogeneity. Leukemia Res 1977; 1: 35–49.
Andersson BS, Bergheim USR, Collins VP, Childs C, Beran M, Sen S, Arden K, Pathak S, Siciliano MJ, Öst A, Freireich EJ . KBM-3, an in vitro model of human acute myelomonocytic leukemia. Exp Hematol 1992; 20: 361–367.
Drexler HG, Dirks WG, MacLeod RAF, Quentmeier H, Steube KG, Uphoff CC (eds). DSMZ Catalogue of Human and Animal Cell Lines, 8th edn, DSMZ: Braunschweig, Germany (2001.
Otsuki T, Wada H, Nakazawa N, Taniwaki M, Kouguchi K, Ohkura M, Uehira K, Isoda K, Yata K, Sakaguchi H, Yawata Y, Ueki A, Yamada O . Establishment of CD7+ human myeloma sister cell lines, KMS-21-PE and KMS-21-BM,carrying t(11;14) and t(8;14). Leuk Lymphoma 2001; 42: 761–774.
Diehl V, Kirchner HH, Schaadt M, Fonatsch C, Stein H, Gerdes J, Boie C . Hodgkin’s disease: establishment and characterization of four in vitro cell lines. J Cancer Res Clin Oncol 1981; 101: 111–124.
Morgan DA, Gumucio DL, Brodsky I . Granulocyte–macrophage colony-stimulating factor-dependent growth and erythropoietin-induced differentiation of a human cell line MB-02. Blood 1991; 78: 2860–2871.
Morgan DA, Class R, Soslau G, Brodsky I . Cytokine-mediated erythroid maturation in megakaryoblastic human cell line HU-3. Exp Hematol 1997; 25: 1378–1385.
Hassan HT, Petershofem E, Lux E, Fonatsch C, Heil G, Freund M . Establishment and characterization of a novel CD34-positive human myeloid leukemia cell line: MHH225 growing in serum-free culture. Ann Hematol 1995; 71: 111–117.
Nagai M, Seki S, Kitahara T, Abe T, Minato K, Watanabe S, Shimoyama M . A novel human myelomonocytoid cell line, P39/TSUGANE, derived from overt leukemia following myelodysplastic syndrome. Gann 1984; 75: 1100–1107.
Bradley TR, Pilkington G, Garson M, Hodgson GS, Kraft N . Cell lines derived from a human myelomonocytic leukaemia. Br J Haematol 1982; 51: 595–604.
Moore GE, Woods LK, Minowada J, Mitchen JR . Establishment of leukemia cell line with T cell characteristics In Vitro. 1973; 8: 434.
Skinnider LF, Pabello P, Zheng CY . Characteristics of a cell line established from a case of acute megakaryoblastic leukemia. Acta Haematol 1997; 98: 26–31.
Tange T, Nakahara K, Mitani K, Yamasaki I, Yasuda H, Tanaka F, Mizuguchi M, Oda H, Yatomi Y, Takanashi R, Fujioka S, Yamaguchi K, Urano Y . Establishment of a human megakaryoblastic cell line (T-33) from chronic myelogenous leukemia in megakaryoblastic crisis. Cancer Res 1988; 48: 6137–6144.
Komatsu N, Nakauchi H, Miwa A, Ishihara T, Eguchi M, Moroi M, Okada M, Sato Y, Wada H, Yawata Y, Suda T, Miura Y . Establishment and characterization of a human leukemic cell line with megakaryocytic features: Dependency on granulocyte–macrophage colony-stimulating factor, interleukin 3, or erythropoietin for growth and survival. Cancer Res 1991; 51: 341–348.
Drewinko B, Mars W, Minowada J, Burk KH, Trujillo JM . ARH–77, an established human IgG-producing myeloma cell line. I. Morphology, B-cell phenotypic marker profile, and expression of Epstein–Barr virus. Cancer 1984; 54: 1883–1892.
Pellat-Deceunynk C, Amiot M, Bataille R, Van Riet I, Van Camp B, Omede P, Boccadoro M . Human myeloma cell lines as a tool for studying the biology of multiple myeloma: a reappraisal 18 years after. Blood 1995; 86: 4001–4002.
Harris NL, Gang DL, Quay SC, Poppema S, Zamecnik PC, Nelson-Rees WA, O‘Brien SI . Comtamination of Hodgkin’s disease cell cultures. Nature 1981; 289: 228–230.
Long JC, Zamecnik PC, Aisenberg AC, Atkins L . Tissue culture studies in Hodgkin’s disease. Morphologic, cytogenetic, cell surface, and enzymatic properties of cultures derived from splenic tumors. J Exp Med 1977; 145: 1484–1500.
Goldstein M, Hoxie J, Zembryki D, Matthews D, Levinson AI . Phenotypic and functional analysis of B cell lines from patients with multiple myeloma. Blood 1985; 66: 444–446.
Arnstein P, Taylor DO, Nelson-Rees WA, Huebner RJ, Lennette EH . Propagation of human tumors in antithymocyte serum-treated mice. J Natl Cancer Inst 1974; 52: 71–84.
Fahey JL, Buell DN, Sox HC . Proliferation and differentiation of lymphoid cells: studies with human lymphoid cell lines and immunoglobulin synthesis. Ann NY Acad Sci 1971; 190: 221–234.
Diehl V, Kirchner HH, Burrichter H, Stein H, Fonatsch C, Gerdes J, Schaadt M, Heit W, Uchanska-Ziegler B, Ziegler A, Heintz F, Sueno K . Characteristics of Hodgkin’s disease-derived cell lines. Cancer Treat Rep 1982; 66: 615–632.
Drexler HG . Recent results on the biology of Hodgkin and Reed-Sternberg cells. II. Continuous cell lines. Leuk Lymphoma 1993; 9: 1–26.
Ritts RE Jr, Ruiz-Arguelles A, Weyl KG, Bradley AL, Weihmeir B, Jacobsen DJ, Strehlo BL . Establishment and characterization of a human non-secretory plasmacytoid cell line and its hybridization with human B cells. Int J Cancer 1983; 31: 133–141.
Moore GE, Grace JT Jr, Citron P, Gerner R, Burns A . Leukocyte cultures of patients with leukemia and lymphomas. NY State J Med 1966; 66: 2757–2764.
Friend C, Marovitz W, Henle G, Henle W, Tsuei D, Hirschhorn K, Holland JG, Cuttner J . Observations on cell lines derived from a patient with Hodgkin’s disease. Cancer Res 1978; 38: 2581–2591.
McCarty TM, Rajaraman S, Elder FF, Gadson P, Thompson EB . Establishment and characterization of a human myeloid cell line from Philadelphia chromosome-negative myeloblastic leukemia arising in a patient with myelodysplastic syndrome. Blood 1987; 70: 1665–1672.
Farnen JP, Tyrkus M, Hanson CA, Cody RL, Emerson SG . Characterization of a new human multiple myeloma cell line, UMJF-2, which suppresses antibody production by B-lymphocytes in vitro. Leukemia 1991; 5: 574–584.
Drexler HG, Matsuo Y . Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia. Leukemia Res 2000; 24: 681–703.
Drexler HG, MacLeod RAF, Borkhardt A, Janssen JWG . Recurrent chromosomal translocations and fusion genes in leukemia–lymphoma cell lines. Leukemia 1995; 9: 480–500.
Wlodarska I, Aventin A, Ingles-Esteve J, Falzetti D, Criel A, Cassiman JJ, Mecucci C, Van den Berghe H, Marynen P . A new subtype of pre-B acute lymphoblastic leukemia with t(5;12) (q31q33;p12), molecularly and cytogenetically distinct from t(5;12) in chronic myelomonocytic leukemia. Blood 1997; 89: 1716–1722.
Broad W, Wade N (eds). Betrayers of the Truth. Fraud and Deceit in Science, Oxford University Press: Oxford (1985.
Masters JR, Thompson JA, Daly-Burns B, Reid YA, Dirks WG, Packer P, Toji LH, Ohno T, Tanabe H, Arlett CF, Kelland LR, Harrison M, Virmani A, Ward TH, Ayres KL, Debenham PG . Short tandem repeat profiling provides an international reference standard for human cell lines. Proc Natl Acad Sci USA 2001; 98: 8012–8017.
Stacey GN, Masters JRW, Hay RJ, Drexler HG, MacLeod RAF, Freshney RI . Cell contamination leads to inaccurate data: We must take action now. Nature 2000; 403: 356.