Failures, re-operations, and complications after autologous chondrocyte implantation – a systematic review

Wood, 2006, Autologous cultured chondrocytes: adverse events reported to the United States Food and Drug Administration, J Bone Joint Surg Am, 88, 503, 10.2106/JBJS.E.00103 Vaccines, Blood & Biologics Gooding, 2006, A prospective, randomized study comparing two techniques of autologous chondrocyte implantation for osteochondral defects in the knee: periosteum covered versus type I/III collagen covered, Knee, 13, 203, 10.1016/j.knee.2006.02.011 Niemeyer, 2008, Characteristic complications after autologous chondrocyte implantation for cartilage defects of the knee joint, Am J Sports Med, 36, 2091, 10.1177/0363546508322131 Gomoll, 2009, Use of a type I/III bilayer collagen membrane decreases reoperation rates for symptomatic hypertrophy after ACI, Am J Sports Med, 37, 20S, 10.1177/0363546509348477 Ferruzzi, 2008, Autologous chondrocyte implantation in the knee joint: open compared with arthroscopic technique. Comparison at a minimum follow-up of five years, J Bone Joint Surg Am, 90, 90, 10.2106/JBJS.H.00633 Obremskey, 2005, Levels of evidence in orthopaedic journals, J Bone Joint Surg Am, 87, 2632, 10.2106/JBJS.E.00370 Brittberg, 1994, Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation, N Engl J Med, 331, 889, 10.1056/NEJM199410063311401 Kon, 2008, Second generation issues in cartilage repair, Sports Med Arthrosc Rev, 16, 221, 10.1097/JSA.0b013e31818cdbc5 Marcacci, 2002, Arthroscopic autologous chondrocyte transplantation: technical note, Knee Surg Sports Traumatol Arthrosc, 10, 154, 10.1007/s00167-001-0275-6 Erggelet, 2010, Autologous chondrocyte implantation versus ACI using 3D-bioresorbable graft for the treatment of large full-thickness cartilage lesions of the knee, Arch Orthop Trauma Surg, 130, 957, 10.1007/s00402-009-0957-y Macmull, 2010, Extended scope of ACI for osteochondral injuries following septic arthritis: a case report, Knee, 17, 242, 10.1016/j.knee.2009.08.013 Nejadnik, 2010, Autologous bone marrow-derived mesenchymal stem cells versus autologous chondrocyte implantation, Am J Sports Med, 1 Della Villa, 2010, Does intensive rehabilitation permit early return to sport without compromising the clinical outcome after arthroscopic ACI in highly competitive athletes?, Am J Sports Med, 38, 68, 10.1177/0363546509348490 Moseley, 2010, Long-term durability of autologous chondrocyte implantation – a multicenter, observational study in US patients, Am J Sports Med, 38, 238, 10.1177/0363546509348000 Vasiliadis, 2010, Autologous chondrocyte implantation in cartilage lesions of the knee – long-term evaluation with MRI and dGEMRIC Imaging technique, Am J Sports Med, 10.1177/0363546509358266 Basad, 2010, Matrix-induced autologous chondrocyte implantation versus microfracture in the treatment of cartilage defects of the knee: a 2-year randomized study, Knee Surg Sports Traumatol Arthrosc, 1 Pérez-Cachafeiro, 2010, Spanish experience in autologous chondrocyte implantation, Open Orthop J, 4, 14, 10.2174/1874325001004010014 Bhosale, 2009, Midterm to long-term longitudinal outcome of autologous chondrocyte implantation in the knee joint: a multilevel analysis, Am J Sports Med, 37, 131S, 10.1177/0363546509350555 Crawford, 2009, An autologous cartilage tissue implant NeoCart for treatment of Grade III Chondral injury to the distal femur, Am J Sports Med, 37, 1334, 10.1177/0363546509333011 Gobbi, 2009, Patellofemoral full-thickness chondral defects treated with second-generation autologous chondrocyte implantation, Am J Sports Med, 37, 1083, 10.1177/0363546509331419 Kon, 2009, Arthroscopic second-generation autologous chondrocyte implantation compared with microfracture for chondral lesions of the knee, Am J Sports Med, 37, S156, 10.1177/0363546509351649 McNickle, 2009, Outcomes of autologous chondrocyte implantation in a diverse patient population, Am J Sports Med, 37, 1344, 10.1177/0363546509332258 Minas, 2009, Increased failure rate of autologous chondrocyte implantation after previous treatment with marrow stimulation techniques, Am J Sports Med, 37, 902, 10.1177/0363546508330137 Nehrer, 2009, Treatment of full-thickness chondral defects with Hyalograft C in the knee: a prospective clinical case series with 2 to 7 years’ follow-up, Am J Sports Med, 37, 81S, 10.1177/0363546509350704 Pascual-Garrido, 2009, Recommendations and treatment outcomes for patellofemoral articular cartilage defects with ACI: prospective evaluation at average 4 year follow-up, Am J Sports Med, 37, 33S, 10.1177/0363546509349605 Saris, 2008, Characterized chondrocyte implantation results in better structural repair when treating symptomatic cartilage defects of the knee in a randomized controlled trial versus microfracture, Am J Sports Med, 36, 235, 10.1177/0363546507311095 Wondrasch, 2009, Effect of accelerated weightbearing after matrix-associated autologous chondrocyte implantation on the femoral condyle on radiographic and clinical outcome after 2 years: a prospective, randomized controlled pilot study, Am J Sports Med, 37, 88S, 10.1177/0363546509351272 Zaslav, 2009, A prospective study of autologous chondrocyte implantation in patients with failed prior treatment for articular cartilage defect of the knee – results of the Study of the Treatment of Articular Repair (STAR) Clinical Trial, Am J Sports Med, 37, 42, 10.1177/0363546508322897 Zeifang, 2009, Autologous chondrocyte implantation using the original periosteum-cover technique versus matrix-associated autologous chondrocyte implantation – a randomized clinical trial, Am J Sports Med, 38, 924, 10.1177/0363546509351499 Minas, 2010, Autologous chondrocyte implantation for joint preservation in patients with early osteoarthritis, Clin Orthop Relat Res, 468, 147, 10.1007/s11999-009-0998-0 Rogers, 2009, Sequential outcome following autologous chondrocyte implantation of the knee: a six-year follow-up, Int Orthop Steinhagen, 2010, Treatment of osteochondritis dissecans of the femoral condyle with autologous bone grafts and matrix-supported autologous chondrocytes, Int Orthop, 34, 819, 10.1007/s00264-009-0841-y Tohyama, 2009, Atelocollagen-associated autologous chondrocyte implantation for the repair of chondral defects of the knee: a prospective multicenter clinical trial in Japan, J Orthop Sci, 14, 579, 10.1007/s00776-009-1384-1 Gigante, 2009, Distal realignment and patellar autologous chondrocyte implantation: mid-term results in a selected population, Knee Surg Sports Traumatol Arthrosc, 17, 2, 10.1007/s00167-008-0635-6 Kim, 2010, Autologous chondrocyte implantation in the knee using fibrin, Knee Surg Sports Traumatol Arthrosc, 18, 528, 10.1007/s00167-009-0905-y Pietschmann, 2009, Cell quality affects clinical outcome after MACI procedure for cartilage injury of the knee, Knee Surg Sports Traumatol Arthrosc, 17, 1305, 10.1007/s00167-009-0828-7 Henderson, 2007, Autologous chondrocyte implantation: superior biologic properties of hyaline cartilage repairs, Clin Orthop Relat Res, 455, 253, 10.1097/01.blo.0000238829.42563.56 Niemeyer, 2008, Autologous chondrocyte implantation for the treatment of retropatellar cartilage defects: clinical results referred to defect localisation, Arch Orthop Trauma Surg, 128, 1223, 10.1007/s00402-007-0413-9 Rosenberger, 2008, Repair of large chondral defects of the knee with autologous chondrocyte implantation in patients 45 years or older, Am J Sports Med, 36, 2336, 10.1177/0363546508322888 Rue, 2008, Prospective evaluation of concurrent meniscus transplantation and articular cartilage repair, Am J Sports Med, 36, 1770, 10.1177/0363546508317122 Vasiliadis, 2008, Chondromatosis of the knee joint 8 months after autologous chondrocyte implantation, Am J Sports Med, 36, 2023, 10.1177/0363546508318194 LaPrade, 2008, Histologic and immunohistochemical characteristics of failed articular cartilage resurfacing procedures for osteochondritis of the knee, Am J Sports Med, 36, 360, 10.1177/0363546507308359 Franceschi, 2008, Simultaneous arthroscopic implantation of autologous chondrocytes and high tibial osteotomy for tibial chondral defects in the varus knee, Knee, 15, 309, 10.1016/j.knee.2008.04.007 Ebert, 2008, Traditional vs accelerated approaches to post-operative rehabilitation following matrix-induced autologous chondrocyte implantation (MACI): comparison of clinical, biomechanical and radiographic outcomes, Osteoarthritis Cartilage, 16, 1131, 10.1016/j.joca.2008.03.010 Farr, 2007, Autologous chondrocyte implantation improves patellofemoral cartilage treatment outcomes, Clin Orthop Relat Res, 463, 187, 10.1097/BLO.0b013e31815576af Mandelbaum, 2007, Treatment outcomes of autologous chondrocyte implantation for full-thickness articular cartilage defects of the trochlea, Am J Sports Med, 35, 915, 10.1177/0363546507299528 Ossendorf, 2007, Treatment of posttraumatic and focal osteoarthritic cartilage defects of the knee with autologous polymer-based three-dimensional chondrocyte grafts: 2 year clinical results, Arthritis Res Ther, 9, R41, 10.1186/ar2180 Steinwachs, 2007, Autologous chondrocyte implantation in chondral defects of the knee with a type I/III collagen membrane: a prospective study with a 3-year follow-up, Arthroscopy, 23, 381, 10.1016/j.arthro.2006.12.003 Farr, 2007, Concomitant meniscal allograft transplantation and autologous chondrocyte implantation, Am J Sports Med, 35, 1459, 10.1177/0363546507301257 Nutsen, 2007, A randomized trial comparing autologous chondrocyte implantation with microfracture – findings at 5 years, J Bone Joint Surg Am, 89A, 2105, 10.2106/JBJS.G.00003 Bhosale, 2007, Combined autologous chondrocyte implantation and allogenic meniscus transplantation: a biological knee replacement, Knee, 14, 361, 10.1016/j.knee.2007.07.002 Robertson, 2007, MRI and clinical evaluation of collagen-covered autologous chondrocyte implantation (CACI) at two years, Knee, 14, 117, 10.1016/j.knee.2006.11.009 Marcacci, 2007, Arthroscopic second-generation autologous chondrocyte implantation, Knee Surg Sports Traumatol Arthrosc, 15, 610, 10.1007/s00167-006-0265-9 Kreuz, 2007, Classification of graft hypertrophy after autologous chondrocyte implantation of full-thickness chondral defects in the knee, Osteoarthritis Cartilage, 15, 1339, 10.1016/j.joca.2007.04.020 Henderson, 2006, Autologous chondrocyte implantation: natural history of postimplantation periosteal hypertrophy and effects of repair-site debridement on outcome, Arthroscopy, 22, 1318, 10.1016/j.arthro.2006.07.057 Marlovits, 2006, Cartilage repair: generations of autologous chondrocyte transplantation, Eur J Radiol, 57, 24, 10.1016/j.ejrad.2005.08.009 Amin, 2006, The use of autologous chondrocyte implantation following and combined with anterior cruciate ligament reconstruction, Int Orthop, 30, 48, 10.1007/s00264-005-0025-3 Krishnan, 2006, Who is the ideal candidate for autologous chondrocyte implantation?, J Bone Joint Surg Br, 88B, 61, 10.1302/0301-620X.88B1.16796 Micheli, 2006, Articular cartilage defects of the distal femur in children and adolescents: treatment with autologous chondrocyte implantation, J Pediatr Orthop, 26, 455, 10.1097/01.bpo.0000224565.72762.eb Behrens, 2006, Matrix-associated autologous chondrocyte transplantation/implantation (MACT/MACI)-5-year follow-up, Knee, 13, 194, 10.1016/j.knee.2006.02.012 Henderson, 2006, Periosteal autologous chondrocyte implantation for patellar chondral defect in patients with normal and abnormal patellar tracking, Knee, 13, 274, 10.1016/j.knee.2006.04.006 Halbrecht, 2006, Improvement in bone homeostasis following autologous chondrocyte implantation of the knee, Orthopedics, 29, 61, 10.3928/01477447-20060101-11 Takahashi, 2006, MR appearance of autologous chondrocyte implantation in the knee: correlation with the knee features and clinical outcome, Skeletal Radiol, 35, 16, 10.1007/s00256-005-0002-3 Fu, 2005, Autologous chondrocyte implantation versus debridement for treatment of full-thickness chondral defects of the knee, Am J Sports Med, 33, 1658, 10.1177/0363546505275148 Mithofer, 2005, Articular cartilage repair in soccer players with autologous chondrocyte transplantation, Am J Sports Med, 33, 1639, 10.1177/0363546505275647 Mithofer, 2005, Functional outcome of knee articular cartilage repair in adolescent athletes, Am J Sports Med, 33, 1147, 10.1177/0363546504274146 Dozin, 2005, Comparative evaluation of autologous chondrocyte implantation and mosaicplasty: a multicenter randomized clinical trial, Clin J Sport Med, 15, 220, 10.1097/01.jsm.0000171882.66432.80 Browne, 2005, Clinical outcome of autologous chondrocyte implantation at 5 years in US subjects, Clin Orthop Relat Res, 436, 237, 10.1097/00003086-200507000-00036 Marcacci, 2005, Articular cartilage engineering with Hyalograft C-3-year clinical results, Clin Orthop Relat Res, 435, 96, 10.1097/01.blo.0000165737.87628.5b Minas, 2005, The role of autologous chondrocyte implantation in the patellofemoral joint, Clin Orthop Relat Res, 436, 30, 10.1097/01.blo.0000171916.40245.5d Bartlett, 2005, Autologous chondrocyte implantation versus matrix-induced autologous chondrocyte implantation for osteochondral defects of the knee – a prospective, randomized study, J Bone Joint Surg Br, 87B, 640, 10.1302/0301-620X.87B5.15905 Bartlett, 2005, Autologous chondrocyte implantation at the knee using a bilayer collagen membrane with bone graft, J Bone Joint Surg Br, 87B, 330, 10.1302/0301-620X.87B3.15552 Henderson, 2005, Autologous chondrocyte implantation for treatment of focal chondral defects of the knee – a clinical, arthroscopic, MRI and histologic evaluation at 2 years, Knee, 12, 209, 10.1016/j.knee.2004.07.002 Marlovits, 2005, Early postoperative adherence of matrix-induced autologous chondrocyte implantation for the treatment of full-thickness cartilage defects of the femoral condyle, Knee Surg Sports Traumatol Arthrosc, 13, 451, 10.1007/s00167-004-0535-3 Visna, 2004, Treatment of deep cartilage defects of the knee using autologous chondrocyte transplantation and by abrasive techniques – a randomized controlled study, Acta Chir Belg, 104, 709, 10.1080/00015458.2004.11679648 Marlovits, 2004, Emergence of Lyme arthritis after autologous chondrocyte transplantation, Arthritis Rheum, 50, 259, 10.1002/art.11446 Henderson, 2004, Reoperation after autologous chondrocyte implantation, J Bone Joint Surg Br, 86B, 205, 10.1302/0301-620X.86B2.14324 Haddo, 2004, The use of chondrogide membrane in autologous chondrocyte implantation, Knee, 11, 51, 10.1016/S0968-0160(03)00041-3 Horas, 2003, Autologous chondrocyte implantation and osteochondral cylinder transplantation in cartilage repair of the knee: a prospective, comparative trial, J Bone Joint Surg Am, 85A, 185, 10.2106/00004623-200302000-00001 Peterson, 2003, Treatment of osteochondritis dissecans of the knee with autologous chondrocyte transplantation: results at two to ten years, J Bone Joint Surg Am, 85A, 17, 10.2106/00004623-200300002-00003 Bentley, 2003, A prospective, randomized comparison of autologous chondrocyte implantation versus mosaicplasty for osteochondral defects in the knee, J Bone Joint Surg Br, 85B, 223, 10.1302/0301-620X.85B2.13543 Briggs, 2003, Histological evaluation of chondral defects after autologous chondrocyte implantation of the knee, J Bone Joint Surg Br, 85B, 1077, 10.1302/0301-620X.85B7.13672 Henderson, 2003, Prospective clinical study of autologous chondrocyte implantation and correlation with MRI at three and 12 months, J Bone Joint Surg Br, 85B, 1060, 10.1302/0301-620X.85B7.13782 Yates, 2003, The effectiveness of autologous chondrocyte implantation for treatment of full-thickness articular cartilage lesions in workers’ compensation patients, Orthopedics, 26, 295, 10.3928/0147-7447-20030301-09 Muellner, 2001, Failed autologous chondrocyte implantation – complete atraumatic graft delamination after two years, Am J Sports Med, 29, 516, 10.1177/03635465010290042301 Micheli, 2001, Autologous chondrocyte implantation of the knee: multicenter experience and minimum 3-year follow-up, Clin J Sports Med, 11, 223, 10.1097/00042752-200110000-00003 Minas, 2001, Autologous chondrocyte implantation for focal chondral defects of the knee, Clin Orthop Relat Res, 391, S349, 10.1097/00003086-200110001-00032 Peterson, 2002, Autologous chondrocyte transplantation: biomechanics and long-term durability, Am J Sports Med, 30, 2, 10.1177/03635465020300011601 Peterson, 2010, Autologous chondrocyte implantation – a long-term follow-up, Am J Sports Med, 38, 1117, 10.1177/0363546509357915 Hostin, 2000, Total hip arthroplasty in patients receiving workers’ compensation, Clin Orthop Relat Res, 379, 161, 10.1097/00003086-200010000-00019 Bosacco, 1995, Results in lumbar disk surgery in a city compensation population, Orthopedics, 18, 351, 10.3928/0147-7447-19950401-08 Weber, 1992, Conflict of the job (returning to work after back injury), TGG Health & Wellness DB – The Black Letter, 7 Vrijland, 2002, Fewer intraperitoneal adhesions with use of hyaluronic acid-carboxymethylcellulose membrane: a randomized clinical trial, Ann Surg, 235, 193, 10.1097/00000658-200202000-00006 Mirzayan, 2006 Jakobsen, 2005, An analysis of the quality of cartilage repair studies, J Bone Joint Surg Am, 87A, 2232, 10.2106/JBJS.D.02904