Failure to conceive in women with CF is associated with pancreatic insufficiency and advancing age

Zolin Flume, 2016, US Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus recommendations for the management of non-tuberculous mycobacteria in individuals with cystic fibrosis, J. Cyst. Fibros., 15, 139, 10.1016/S1569-1993(16)00018-7 Kazmerski, 2017, Sexual and reproductive health behaviors and experiences reported by young women with cystic fibrosis, J. Cyst. Fibros., 17, 57 Durieu, 2015, Patients becoming parents: reproduction and pregnancy, 119 Kopito, 1973, Water and electrolytes in cervical mucus from patients with cystic fibrosis, Fertil. Steril., 24, 512, 10.1016/S0015-0282(16)39790-4 Oppenheimer, 1970, Cervical mucus in cystic fibrosis: a possible cause of infertility, Am. J. Obstet. Gynecol., 108, 673, 10.1016/0002-9378(70)90254-1 Gervais, 1996, Hypofertility with thick cervical mucus: another mild form of cystic fibrosis?, JAMA, 276, 1638, 10.1001/jama.1996.03540200024023 Chan, 2002, Distribution and regulation of ENaC subunit and CFTR mRNA expression in murine female reproductive tract, J. Membr. Biol., 185, 165, 10.1007/s00232-001-0117-y Tizzano, 1994, Differential cellular expression of cystic fibrosis transmembrane regulator in human reproductive tissues. Clues for the infertility in patients with cystic fibrosis, Am. J. Pathol., 144, 906 Johannesson, 1997, Cystic fibrosis mRNA expression in rat brain: cerebral cortex and medial preoptic area, Neuroreport, 8, 535, 10.1097/00001756-199701200-00031 Arrigo, 2003, Pubertal development in cystic fibrosis: an overview, J. Pediatr. Endocrinol. Metab., 16, 267 Johannesson, 1998, Female patients with cystic fibrosis suffer from reproductive endocrinological disorders despite good clinical status, Hum. Reprod., 13, 2092, 10.1093/humrep/13.8.2092 Hampl, 2011, Antimüllerian hormone (amh) not only a marker for prediction of ovarian reserve, Physiol. Res., 60, 217 Schram, 2015, Cystic fibrosis (cf) and ovarian reserve: a cross-sectional study examining serum anti-mullerian hormone (amh) in young women, J. Cyst. Fibros., 14, 398, 10.1016/j.jcf.2014.09.008 Lemonnier, 2013, WS18.1 Evolution of pregnancies in the French CF Registry: 1992–2011, J. Cyst. Fibros., 12, S36, 10.1016/S1569-1993(13)60109-5 Ben Lulu A, Blumenfeld Z, Livnat G, Gur M, Bentur L, Mussaffi H, Blau H, Sarouk I, Efrati O, Cohen- Cymberknoh M, Kerem E, Aviram M, Pickard E, Shteinberg M, Ben Lulu A, Blumenfeld Z, Livnat G, Gur M, Bentur L, Mussaffi H, Blau H, Sarouk I, Efrati O, Cohe SM. Infertility among women with cystic fibrosis: Prevalence and risk factors. The 39th European Cystic Fibrosis Conference. Vol Basel, Switzerland; 2016. De Boeck, 2006, Cystic fibrosis: terminology and diagnostic algorithms, Thorax, 61, 627, 10.1136/thx.2005.043539 Practice Committee of American Society for Reproductive Medicine, 2013, Definitions of infertility and recurrent pregnancy loss: a committee opinion, Fertil. Steril., 99, 63, 10.1016/j.fertnstert.2012.09.023 CFTR2@Johns Hopkins - Home Page. 2013(12/27/2013). Cystic Fibrosis Mutation Database. http://www.genet.sickkids.on.ca/home.svc. Accessed January 1, 2018. Fanen, 2014, Genetics of cystic fibrosis: CFTR mutation classifications toward genotype-based CF therapies, Int. J. Biochem. Cell Biol., 52, 94, 10.1016/j.biocel.2014.02.023 Lee, 2003, Evaluation of a new definition for chronic Pseudomonas aeruginosa infection in cystic fibrosis patients, J. Cyst. Fibros., 2, 29, 10.1016/S1569-1993(02)00141-8 Bilton, 2011, Pulmonary exacerbation: towards a definition for use in clinical trials. Report from the EuroCareCF Working Group on outcome parameters in clinical trials, J. Cyst. Fibros., 10, S79, 10.1016/S1569-1993(11)60012-X Kazmerski, 2017, Attitudes and Decision making Related to Pregnancy among Young Women with Cystic Fibrosis, Matern. Child Health J., 21, 818, 10.1007/s10995-016-2181-z Edenborough, 2000, The outcome of 72 pregnancies in 55 women with cystic fibrosis in the United Kingdom 1977-1996, BJOG, 107, 254, 10.1111/j.1471-0528.2000.tb11697.x Edenborough, 2008, Guidelines for the management of pregnancy in women with cystic fibrosis, 7 Thorpe-Beeston, 2013, The outcome of pregnancies in women with cystic fibrosis-single centre experience 1998-2011, BJOG An Int J Obstet Gynaecol, 120, 354, 10.1111/1471-0528.12040 2013, NICE Clin Guidel Münster, 2018, Who is the gate keeper for treatment in a fertility clinic in Germany? -baseline results of a prospective cohort study (PinK study), BMC Pregnancy Childbirth, 18, 62, 10.1186/s12884-018-1690-8 Kerem, 1996, Genotype- phenotype correlations in cystic fibrosis, Pediatr. Pulmonol., 22, 387, 10.1002/(SICI)1099-0496(199612)22:6<387::AID-PPUL7>3.0.CO;2-G ESHRE Capri Workshop Group, 2006, Nutrition and reproduction in women, Hum. Reprod. Update, 12, 193, 10.1093/humupd/dmk003