Factors associated with Health-Related Quality of Life in Kidney Transplant Recipients in France

BMC Nephrology - Tập 19 - Trang 1-12 - 2018
Yosra Mouelhi1, Elisabeth Jouve2, Marine Alessandrini1, Nathalie Pedinielli2, Valérie Moal3, Aurélie Meurette4, Elisabeth Cassuto5, Georges Mourad6, Antoine Durrbach7, Bertrand Dussol3, Stéphanie Gentile1,2
1Laboratoire de Santé Publique, Faculté de Médecine, Université Aix-Marseille, Marseille, France
2Service Santé Publique et Information Médicale, CHU Marseille, Marseille, France
3Centre de Néphrologie et de Transplantation Rénale, CHU Marseille, Marseille, France
4Transplantation, Urology and Nephrology Institute (ITUN), CHU Nantes, Nantes, France
5Hôpital Pasteur, Nice, France
6Département de Néphrologie, Dialyse et Transplantation, CHU Montpellier, Montpellier, France
7Service de Néphrologie, CHU Bicêtre, Paris, France

Tóm tắt

Health-Related Quality of Life (HRQoL) assessment after kidney transplantation has become an important tool in evaluating outcomes. This study aims to identify the associated factors with HRQoL among a representative sample size of Kidney Transplant Recipients (KTR) at the time of their inclusion in the study. Data of this cross-sectional design is retrieved from a longitudinal study conducted in five French kidney transplant centers in 2011, and included KTR aged 18 years with a functioning graft for at least 1 year. Measures include demographic, psycho-social and clinical characteristics. To evaluate HRQoL, the Short Form-36 Health Survey (SF-36) and a HRQoL instrument for KTR (ReTransQol) were administered. Multivariate linear regression models were performed. A total of 1424 patients were included, with 61.4% males, and a mean age of 55.7 years (±13.1). Demographic and clinical characteristics were associated with low HRQoL scores for both questionnaires. New variables were found in our study: perceived poor social support and being treated by antidepressants were associated with low scores of Quality of Life (QoL), while internet access was associated with high QoL scores. The originality of our study’s findings was that psycho-social variables, particularly KTR treated by antidepressants and having felt unmet needs for any social support, have a negative effect on their QoL. It may be useful to organize a psychological support specifically adapted for patients after kidney transplantation.

Tài liệu tham khảo

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