Factors Associated With Death in Critically Ill Patients With Coronavirus Disease 2019 in the US

JAMA Internal Medicine - Tập 180 Số 11 - Trang 1436 - 2020
Shruti Gupta1, Salim S. Hayek2, Wei Wang3, Lili Chan4, Kusum S. Mathews5,6, Michal L. Melamed7, Samantha K. Brenner8,9, Amanda K. Leonberg‐Yoo10, Edward J. Schenck11, Jared Radbel12, Jochen Reiser13, Anip Bansal14, Anand Srivastava15, Yan Zhou16, Anne Sutherland17, Adam Green18, Ishaan Vohra19, Nitender Goyal20, Anitha Vijayan21, Juan Carlos Q. Velez22,23, Shahzad Shaefi24, Chirag R. Parikh25, Justin Arunthamakun26, Ambarish M. Athavale27, Allon N. Friedman28, Samuel Short29, Zoé A. Kibbelaar30, Samah Abu Omar1, Andrew J. Admon31,32, John P. Donnelly33,32, Hayley B. Gershengorn34,35, Miguel A. Hernán36,37,38, Matthew W. Semler39, David E. Leaf1, Carl P. Walther40, Samaya J. Anumudu40, Kathleen F. Kopecky40, Gregory P. Milligan40, Peter A. McCullough40, Thuy-Duyen Nguyen40, Megan L. Krajewski40, Sidharth Shankar40, Ameeka Pannu40, Sushrut S. Waikar40, Peter C. Hart40, Oyintayo Ajiboye40, M. Itteera40, Jean‐Sebastien Rachoin40, Christa Schorr40, Lisa Shea40, Daniel Edmonston40, Christopher L. Mosher40, Aaron Karp40, Zaza Cohen40, Valerie Allusson40, Gabriela Bambrick‐Santoyo40, Noor ul aain Bhatti40, Bijal Mehta40, Aquino Williams40, Patricia Walters40, Rolando C Go40, Keith Rose40, Amy M. Zhou40, Ethan C. Kim40, Rebecca Lisk40, Steven G. Coca40, Deena R. Altman40, Aparna Saha40, Howard Soh40, Huei Hsun Wen40, Sonali Bose40, Emily Leven40, Jing G. Wang40, Gohar Mosoyan40, Girish N. Nadkarni40, John Guirguis40, Rajat Kapoor40, Christopher Meshberger40, Brian T. Garibaldi40, Avi Z. Rosenberg40, Yumeng Wen40, Steven Menez40, Rubab F. Malik40, Carmen Elena Cervantes40, Samir C. Gautam40, Hang Nguyen40, Afshin Ahoubim40, Leslie F. Thomas40, Dheeraj Reddy Sirganagari40, Pramod Guru40, Paul A. Bergl40, Jesús Rodríguez40, Jatan A. Shah40, Mrigank S. Gupta40, Princy Kumar40, Deepa G. Lazarous40, Seble Kassaye40, Tanya S. Johns40, Ryan Mocerino40, Kalyan Prudhvi40, Denzel Zhu40, Rebecca V. Levy40, Yorg Azzi40, Molly Fisher40, Milagros Yunes40, Kaltrina Sedaliu40, Ladan Golestaneh40, Maureen Brogan40, Ritesh Raichoudhury40, Soo Jung Cho40, Maria Plataki40, Sergio Alvarez-Mulett40, Luis G. Gómez-Escobar40, Di Pan40, Stefi Lee40, Jamuna Kirshnan40, William Whalen40, David M. Charytan40, Ashley Macina40, Daniel W. Ross40, Alexander S. Leidner40, Carlos Ruiz Martínez40, Jacqueline M. Kruser40, Richard G. Wunderink40, Alexander J. Hodakowski40, Eboni G. Price‐Haywood40, Luis A. Matute-Trochez40, Anne E Hasty40, Muner Mohamed40, Rupali S. Avasare40, David Zonies40, Rebecca M. Baron40, Meghan E. Sise40, Erik T. Newman40, Kapil K. Pokharel40, Simon Correa40, Harkarandeep Singh40, Tanveer Shaukat40, Omer Kamal40, Heather Yang40, Benjamin G. Wu40, Meghan Lee40, Ian A. Strohbehn40, Jiahua Li40, Saif A. Muhsin40, Ernest I. Mandel40, Ariel Mueller40, Nicholas S. Cairl40, Chris Rowan40, Farah Madhai-Lovely40, Vasil Peev40, John J. Byun40, Andrew Vissing40, Esha M. Kapania40, Zoë Post40, Nilam Patel40, Amee Patrawalla40, Sowminya Arikapudi40, Barbara A. Danek40, Jeffery M Paer40, Isha Puri40, Jag Sunderram40, Matthew T. Scharf40, Ayesha Ahmed40, Ilya Berim40, Sabiha Hussain40, Shuchi Anand40, Joseph E. Levitt40, Pablo García40, Suzanne M. Boyle40, Rui Song40, Jingjing Zhang40, Moh’d A. Sharshir40, Vadym V. Rusnak40, Amber S. Podoll40, Michel Chonchol40, Sunita Sharma40, Arash Rashidi40, Rana Hejal40, Erik T Judd40, Laura Latta40, Ashita J. Tolwani40, Timothy E. Albertson40, Jason Y. Adams40, Etienne Macedo40, Rebecca M. Beutler40, Carl E. Schulze40, Harin Rhee40, Kathleen D. Liu40, Vasantha Jotwani40, Jay L. Koyner40, Chintan V. Shah40, Vishal Jaikaransingh40, Stephanie M. Toth‐Manikowski40, Min J. Joo40, James P. Lash40, Javier A. Neyra40, Nourhan Chaaban40, Alfredo Iardino40, Elizabeth H. Au40, Jill H. Sharma40, Marie Anne Sosa40, Sabrina Taldone40, Gabriel Contreras40, David De La Zerda40, Pennelope Blakely40, Hanna Berlin40, Tariq U. Azam40, Husam Shadid40, Michael Pan40, Patrick O’Hayer40, Chelsea Meloche40, Rafey Feroze40, Abbas Bitar40, Jennifer E. Flythe40, Matthew J. Tugman40, Brent R. Brown40, Ryan Spiardi40, Todd A. Miano40, Meaghan S. Roche40, Charles R. Vasquez40, Amar D. Bansal40, Natalie C. Ernecoff40, Csaba P. Kövesdy40, S. Susan Hedayati40, Mridula Nadamuni40, Sadaf Khan40, DuWayne L. Willett40, Amanda D. Renaghan40, Pavan K. Bhatraju40, Bilal Malik40, Christina Mariyam Joy40, Tingting Li40, Seth Goldberg40, Patricia F. Kao40, Greg Schumaker40, Anthony J. Faugno40, Caroline M. Hsu40, Asma Tariq40, Leah Meyer40, Daniel E. Weiner40, Marta Christov40, F. Perry Wilson40, Tanima Arora40, Ugochukwu Ugwuowo40
1Division of Renal Medicine, Brigham and Women's Hospital, Boston, Massachusetts
2Division of Cardiology, Department of Medicine, University of Michigan, Ann Arbor
3Department of Medicine, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts
4Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York
5Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, New York
6Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York
7Montefiore Medical Center, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York
8Department of Internal Medicine, Hackensack Meridian School of Medicine at Seton Hall, Nutley, New Jersey
9Heart and Vascular Hospital, Hackensack Meridian Health Hackensack University Medical Center, Hackensack, New Jersey
10Renal-Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia
11Divison of Pulmonary and Critical Care Medicine, Department of Medicine, Weill Cornell Medicine, New York, New York
12Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey
13Department of Medicine, Rush University Medical Center, Chicago, Illinois
14Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora
15Center for Translational Metabolism and Health, Institute for Public Health and Medicine, Division of Nephrology and Hypertension, Northwestern University Feinberg School of Medicine
16Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Medical College of Wisconsin, Milwaukee
17Division of Pulmonary and Critical Care Medicine, Rutgers New Jersey Medical School, Newark
18Cooper University Health Care, Camden, New Jersey
19Department of Medicine, Hackensack Meridian Health Mountainside Medical Center, Glen Ridge, New Jersey
20Division of Nephrology, Tufts Medical Center, Boston, Massachusetts
21Division of Nephrology, Washington University in St. Louis, St. Louis, Missouri;
22Department of Nephrology, Ochsner Health System, New Orleans, Louisiana
23Ochsner Clinical School, The University of Queensland, Brisbane, Queensland, Australia
24Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts
25Division of Nephrology, Johns Hopkins School of Medicine, Baltimore, Maryland
26Division of Cardiology, Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas
27Division of Nephrology, Cook County Health, Chicago, Illinois
28Department of Medicine, Indiana University School of Medicine, Indianapolis
29Larner College of Medicine, University of Vermont, Burlington
30Renal Section, Boston Medical Center, Boston, Massachusetts
31Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor
32Institute for Healthcare Policy & Innovation, University of Michigan, Ann Arbor
33Department of Learning Health Sciences, University of Michigan Medical School, Ann Arbor
34Division of Critical Care Medicine, Albert Einstein College of Medicine, Bronx, New York
35Division of Pulmonary, Critical Care, and Sleep Medicine, University of Miami Miller School of Medicine, Miami, Florida
36Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts
37Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts
38Harvard–Massachusetts Institute of Technology Division of Health Sciences and Technology, Boston, Massachusetts
39Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
40for the STOP-COVID Investigators

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Tài liệu tham khảo

Wang, 2020, Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China., JAMA, 323, 1061, 10.1001/jama.2020.1585

Yang, 2020, Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study., Lancet Respir Med, 8, 475, 10.1016/S2213-2600(20)30079-5

Grasselli, 2020, Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region, Italy., JAMA, 323, 1574, 10.1001/jama.2020.5394

Bhatraju, 2020, Covid-19 in critically ill patients in the Seattle region: case series., N Engl J Med, 382, 2012, 10.1056/NEJMoa2004500

Goyal, 2020, Clinical characteristics of Covid-19 in New York City., N Engl J Med, 382, 2372, 10.1056/NEJMc2010419

Richardson, 2020, Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area., JAMA, 323, 2052, 10.1001/jama.2020.6775

Vincent, 1996, The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure: on behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine., Intensive Care Med, 22, 707, 10.1007/BF01709751

Klok, 2020, Incidence of thrombotic complications in critically ill ICU patients with COVID-19., Thromb Res, 191, 145, 10.1016/j.thromres.2020.04.013

Helms, 2020, High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study., Intensive Care Med, 46, 1089, 10.1007/s00134-020-06062-x

Middeldorp, Incidence of venous thromboembolism in hospitalized patients with COVID-19., J Thromb Haemost

Lodigiani, 2020, Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy., Thromb Res, 191, 9, 10.1016/j.thromres.2020.04.024

Desborough, 2020, Image-proven thromboembolism in patients with severe COVID-19 in a tertiary critical care unit in the United Kingdom., Thromb Res, 193, 1, 10.1016/j.thromres.2020.05.049

Zhang, 2019, The cumulative venous thromboembolism incidence and risk factors in intensive care patients receiving the guideline-recommended thromboprophylaxis., Medicine (Baltimore), 98, 10.1097/MD.0000000000015833

Kollias, 2020, Thromboembolic risk and anticoagulant therapy in COVID-19 patients: emerging evidence and call for action., Br J Haematol, 189, 846, 10.1111/bjh.v189.5

Wu, 2020, Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China., JAMA Intern Med, 180, 934, 10.1001/jamainternmed.2020.0994

Verity, 2020, Estimates of the severity of coronavirus disease 2019: a model-based analysis., Lancet Infect Dis, 20, 669, 10.1016/S1473-3099(20)30243-7

Mo, 2020, Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China., Clin Infect Dis, 10.1093/cid/ciaa270

Lighter, 2020, Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission., Clin Infect Dis, 10.1093/cid/ciaa415

Simonnet, 2020, High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation., Obesity (Silver Spring), 10.1002/oby.22831

Kass, 2020, Obesity could shift severe COVID-19 disease to younger ages., Lancet, 395, 1544, 10.1016/S0140-6736(20)31024-2

Price-Haywood, 2020, Hospitalization and mortality among black patients and white patients with Covid-19., N Engl J Med, 10.1056/NEJMsa2011686

van Walraven, 2011, Administrative database research infrequently used validated diagnostic or procedural codes., J Clin Epidemiol, 64, 1054, 10.1016/j.jclinepi.2011.01.001

Jehi, 2020, Individualizing risk prediction for positive COVID-19 testing: results from 11,672 patients., Chest

Johns Hopkins University. Coronavirus Resource Center. Accessed June 19, 2020. https://coronavirus.jhu.edu/

Mohamed? MMB, Lukitsch? I, Torres-Ortiz? AE, . Acute kidney injury associated with coronavirus disease 2019 in urban New Orleans. Kidney360. Published online May 13, 2020. Accessed July 9, 2020. https://kidney360.asnjournals.org/content/early/2020/05/13/KID.0002652020

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JAMA Internal Medicine

Tập 180 Số 11

1436

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