Factors Affecting Drug Withholding Time Estimates in Horses

Diane F. Gerken1
1From the Department of Veterinary Physiology and Pharmacology, The Ohio State University College of Veterinary Medicine, Columbus, Ohio

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Anon: Race Track Division Schedule of Drugs 1991. Agriculture Canada, 1991 Baggot, 1977, 102 Blake, 1973, GLC and the electron capture detector, American Laboratory, 5, 63 Booth, 1988, 1157 Burrows, 1989, Interactions between chloramphenicol, acepromazine, phenylbutazone, rifampin and thiamylal in the horse, Equine Vet J, 21, 34, 10.1111/j.2042-3306.1989.tb02086.x Chay, 1984, Population distributions of phenylbutazone and oxyphenbutazone after oral and i.v. dosing in horses, J Vet Pharmacol Ther, 7, 265, 10.1111/j.1365-2885.1984.tb00911.x Christenson, 1985, Effects of oral cimetidine on plasma concentrations of phenylbutazone in horses, J Vet Pharmacol Ther, 8, 404, 10.1111/j.1365-2885.1985.tb00974.x Chui YC, Mutlib A, Esaw B, et al: Detection of detomidine and its metabolites in equine plasma and urine. In Proceedings of the 9th International Conference of Racing Analysts and Veterinarians. New Orleans, 1992, p 85 Clarke, 1992, Pharmacokinetics of gentamicin and antipyrine in the horse: Effect of advancing age, J Vet Pharmacol Ther, 15, 309, 10.1111/j.1365-2885.1992.tb01022.x Engvall, 1971, Enzyme linked immunosorbent assay (ELISA): quantitative assay of IgG, Immunochemistry, 8, 871, 10.1016/0019-2791(71)90454-X Frincke, 1980, The major metabolite of fentanyl in the horse, Drug Metab Dispos, 8, 425 Gabriel, 1962, Phenylbutazone: Short-term versus long-term administration to thoroughbreds and standardbreds, J Am Vet Med Assoc, 14, 337 Gerring, 1981, Pharmacokinetics of phenylbutazone and its metabolites in the horse, Equine Vet J, 13, 152, 10.1111/j.2042-3306.1981.tb03472.x Gerken, 1985, Inhibitory effects of intravenous chloramphenicol sodium succinate on the disposition of phenylbutazone in horses, J Pharmacokin Biopharm, 13, 467, 10.1007/BF01059330 Gerken, 1991, Urinary pH effects on the renal clearance of lidocaine and phenylbutazone in exercising horses, The Toxicologist, 11, 97 Houston, 1985, Phenylbutazone and its metabolites in plasma and urine of thoroughbred horses: population distributions and the effects of urinary pH, J Vet Pharmacol Ther, 8, 136, 10.1111/j.1365-2885.1985.tb00937.x Jenny, 1979, Pharmacokinetic interaction of isopropylaminophenazone and phenylbutazone in the horse, J Vet Pharmacol Ther, 2, 101, 10.1111/j.1365-2885.1979.tb00361.x Kaneko, 1989, 900 Lees, 1985, Phenylbutazone in the horse, Vet Rec, 116, 229, 10.1136/vr.116.9.229 Maylin GA: Microtechniques in thin layer chromatography. In Proceedings of the 3rd International Conference of Racing Analysts and Veterinarians. Lexington, KY, 1979, p 3 Maylin, 1974, Disposition of phenylbutazone in the horse, Proc AAEP, 20, 243 McKeever, 1991, Atrial natriuretic peptide during exercise in horses, 368 Mendonça M, Ryan M, Todi F: Glycopyrrolate: detection and elimination in the horse. In Proceedings of the 9th International Conference of Racing Analysts and Veterinarians. New Orleans, 1992, p 327 Moss, 1973, Persistence of phenylbutazone in horses producing acid urines, Vet Rec, 93, 124, 10.1136/vr.93.5.124 Mutlib, 1992, Characterization of xylazine metabolites produced in vivo and in vitro by LC/MS/MS and GC/MS, Drug Metab Dispos, 20, 840 Piperno, 1968, Plasma and urine levels of phenylbutazone in the horse, J Am Vet Med Assoc, 153, 195 Rose, 1982, Bioavailability of phenylbutazone preparations in the horse, Equine Vet J, 14, 234, 10.1111/j.2042-3306.1982.tb02404.x Schott, 1991, Renal responses to high intensity exercise, 361 Smith, 1987, The bioavailability of phenylbutazone in the horse, Xenobiotica, 17, 435, 10.3109/00498258709043950 Smyth, 1990, Pharmacokinetic studies of cimetidine in adult horses, Equine Vet J, 22, 48, 10.1111/j.2042-3306.1990.tb04206.x Snow, 1982, Paste formulation of phenylbutazone, Vet Rec, 111, 353, 10.1136/vr.111.15.353-a Snow, 1982, Paste formulations of phenylbutazone, Vet Rec, 111, 468, 10.1136/vr.111.15.353-a Snow, 1983, Studies on a new paste preparation of phenylbutazone, Vet Rec, 112, 602, 10.1136/vr.112.26.602 Soma, 1985, Plasma and serum concentrations of phenylbutazone and oxyphenbutazone in racing Thoroughbreds 24 hours after treatment with various dosage regimens, Am J Vet Res, 46, 932 Soma LR, Felsburg P, Hopkins J, et al: Enzyme-linked immunoassay (ELISA) for the detection and quantitation of fentanyl: Prototype for a unique system. In Proceedings of the 7th International Conference of Racing Analysts and Veterinarians. Lexington, KY, 1988, p 135 Stevenson, 1990, The influence of furosemide on plasma elimination and urinary excretion of drugs in standardbred horses, J Vet Pharmacol Ther, 13, 93, 10.1111/j.1365-2885.1990.tb00753.x Sullivan, 1982, Factors affecting absorption of non-steroidal anti-inflammatory agents in the horse, Vet Rec, 110, 554, 10.1136/vr.110.24.554 Tobin, 1977, Drug interactions in the horse: effects of chloramphenicol, quinidine, and oxyphenbutazone on phenylbutazone metabolism, Am J Vet Res, 38, 123 Tobin, 1982, “Detection times” and “clearance times” for drugs in horses and other animals, J Vet Pharmacol Ther, 5, 195, 10.1111/j.1365-2885.1982.tb00431.x Tobin, 1986, Phenylbutazone in the horse: A review, J Vet Pharmacol Ther, 9, 1, 10.1111/j.1365-2885.1986.tb00008.x Van Weemen, 1971, Immunoassay using antigen-enzyme conjugates, FEBS Letters, 15, 232, 10.1016/0014-5793(71)80319-8 Weckman TJ, Tobib T, Tai H-H, et al: Detection of fentanyl and fentanyl derivatives using radioimmunoassay and enzyme-linked immunosorbent assay. In Proceedings of the 7th International Conference of Racing Analysts and Veterinarians. Lexington, KY, 1988, p 123 Woods, 1985, Effects of phenylbutazone and oxyphenbutazone on basic drug detection in high performance thin layer chromatographic systems, J Vet Pharmacol Ther, 8, 181, 10.1111/j.1365-2885.1985.tb00942.x