Facile synthesis and biological evaluation of heterocyclic compounds containing Diazepam

Aboulwafa, O. M. and Berto, A. G., Synthesis, and antimicrobial activity of Benzo[b]thienyl-1,3,4-oxadiazole, 1,2,4-triazole and thidiazole derivatives.Arch. Die Pharm., 325, 123–127 (1992). Berghot, M. A., Hanna, M. A., and Girges, M. M., Synthesis, Spectral and biological studies of some heterocyclic systems containing anthraquinone.Pharmazie, 47, 340–343 (1993). Berghot, M. A., Heterocyclic groups annulated to 1,4-benzodiazepine systems.Arch. Die Pharm., 325, 285–289 (1992). Cruickshank, R., Duguid, J. P., and Swin, R. L., The practice of medicinal microbiology, Livingstone, London (1975). El-Sayed, O. A., Farghaly, A. M., Habib, N. S., and Khalil, M.A., Synthesis, Anti-microbial activities of novel triazolo-quinolines.Arch. Die Pharm., 324, 249–253 (1991). Goeres, E., Hilgetag, G., and Jung, F., The anticonvulsive action of acetazolamide and its derivatives. Acta physiol.Acad. Sci. Hung., 19, 95–102 (1961). Griffin, D. A. and Sally, K., Preparation of Substituted trinzalylbutanoates as plant growth regulators.Eur. pat. Appl. 199474 (1986), C. A. 106, 98120u (1987). Hara, T., Kayama, Y., Mori, T., Itoh, K., Fujimori, H., Sunami, T., Hashimoto, Y., and Ishimoto, S., Synthesis and biological action of 6-phenyl-pyrrolo[1,2-a][1,4]benzodiazepines.J. Med. Chem., 21, 263–266 (1978). Haffman F., The Roch vandemecumm Roch products or the Egyptian Market. Basel, Switzerland (1980). Krutovskikh, G. N., Rusanov, A. M., Gormeua, G. F., Vatanyam, L. P., and Kolesova, M. B., Radioprotective effect of thiadiazole derivatives.UUSR Khim. Farm. Zh., 11(4), 48–53 (1977). Miyadera, T., Kawamo, Y., Hata, T., Tamur, C., and Tachlkawa R., Reactions of chlorodiazepoxide and diazepamN-oxide with dimethyl acetylene dicarboxylate.Chem. Pharm. Bull., 25, 3247–3251 (1977). Mogilaiah, K., Sveenivasulu, B., and Rao, R.G., Synthesis and antimicrobial activity of 1,3,4-oxadiazolyl-1,8-naphtho pyridines.Indian J. Chem., 35B, 339–344 (1996). Nakajima, R., Take, T. and Nagawa, Y., Pharmacological studies of 6-(4-methyl-1-piprazinyl)morphanthridine.J. Pharmacol., 21, 497–500 (1971). Omodel-Sale, A., Cansonni, P., and Galliani, G., Synthesis and contragestational activity of 3,5-diaryl-S-triazoles.J. Med. Chem. 26, 1187–1189 (1983). Parekh, H. and Trivedi, S., Synthesis of thiadiazole and triazole derivatives as potential antimicrobial agents.Indian J. Chem., 33B, 295–297 (1994). Saad, H., Synthesis of some phyridyloxymethyloxadiazoles, thiadiazole and triazoles of expected pharmacological activity.Indian J. Chem. 35B, 980–985 (1986). Sawhney, S. N., Sharma, P. K., Gupta, S., Singh, G. B., and Starang, B., Synthesis and antiinflammatory activity of some oxadiazoles, thiazoles and triazoles derivatives.Indian J. Chem., 32B, 1190–1195 (1993). Skagins, K. and Zetterberg, B., Antibacterial activity of some compounds structurally related to 1-benzyloxy thiocabonyl-2-salicylidene hydrazine.Antibiot. Chemotherapy, 10, 31–36 (1961). Stefanovich, V. and Cerprini, M., Biological properties of fused heterocyclic Diazepam.J. Pharm. Sci., 60, 78–81 (1971). Sternbach, L. H., The benzodiazepine story.Prog. Drug Res., 22, 229–232 (1978). Sternbach, L. H., The benzodiazepine story.J. Med. Chem., 22, 1–7 (1979). Tanaka, G., Biological active of triazole derivatives., Jpan Kokai 7495973 (1974), C.A. 82, 156320h (1975). Vashi, B. S., Mehta, D. S., and Shah, V.H., Synthesis of 2,5-disubstituted-1,3,4-oxadiazole, 1,3,4-triazole and 1,3,4-thiadiazole derivatives as potential antimicrobial agents.Indian J. Chem., 35B, 111–115 (1996).