FK506-binding protein (FKBP12) regulates ryanodine receptor-evoked Ca2+ release in colonic but not aortic smooth muscle

Bootman, 2001, Calcium signalling—an overview, Semin. Cell Dev. Biol., 12, 3, 10.1006/scdb.2000.0211

Bolton, 1999, Excitation-contraction coupling in gastrointestinal and other smooth muscles, Annu. Rev. Physiol., 61, 85, 10.1146/annurev.physiol.61.1.85

McCarron, 2006, Ca2+ microdomains in smooth muscle, Cell Calcium, 40, 461, 10.1016/j.ceca.2006.08.010

Burdyga, 2005, Action potential refractory period in ureter smooth muscle is set by Ca sparks and BK channels, Nature, 436, 559, 10.1038/nature03834

Nelson, 1995, Relaxation of arterial smooth muscle by calcium sparks, Science, 270, 633, 10.1126/science.270.5236.633

McCarron, 2002, Agonist-induced phasic and tonic responses in smooth muscle are mediated by InsP3, J. Cell Sci., 115, 2207, 10.1242/jcs.115.10.2207

Gordienko, 2002, Crosstalk between ryanodine receptors and IP3 receptors as a factor shaping spontaneous Ca2+-release events in rabbit portal vein myocytes, J. Physiol., 542, 743, 10.1113/jphysiol.2001.015966

Imaizumi, 1998, Ca2+ images and K+ current during depolarization in smooth muscle cells of the guinea-pig vas deferens and urinary bladder, J. Physiol., 510, 705, 10.1111/j.1469-7793.1998.705bj.x

Collier, 2000, Calcium-induced calcium release in smooth muscle: loose coupling between the action potential and calcium release, J. Gen. Physiol., 115, 653, 10.1085/jgp.115.5.653

Burdyga, 1995, Major difference between rat and guinea-pig ureter in the ability of agonists and caffeine to release Ca2+ and influence force, J. Physiol., 489, 327, 10.1113/jphysiol.1995.sp021054

Ganitkevich, 1995, Efficacy of peak Ca2+ currents ICa as trigger of sarcoplasmic reticulum Ca2+ release in myocytes from the guinea-pig coronary artery, J. Physiol., 484, 287, 10.1113/jphysiol.1995.sp020665

Ganitkevich, 1992, Contribution of Ca2+-induced Ca2+ release to the [Ca2+]i transients in myocytes from guinea-pig urinary bladder, J. Physiol., 458, 119, 10.1113/jphysiol.1992.sp019409

Fill, 2002, Ryanodine receptor calcium release channels, Physiol. Rev., 82, 893, 10.1152/physrev.00013.2002

McPherson, 1993, The ryanodine receptor/Ca2+ release channel, J. Biol. Chem., 268, 13765, 10.1016/S0021-9258(19)85166-9

Mironneau, 2001, Contribution of ryanodine receptor subtype 3 to Ca2+ responses in Ca2+-overloaded cultured rat portal vein myocytes, J. Biol. Chem., 276, 11257, 10.1074/jbc.M005994200

Jayaraman, 1992, FK506 binding protein associated with the calcium release channel (ryanodine receptor), J. Biol. Chem., 267, 9474, 10.1016/S0021-9258(19)50114-4

Carmody, 2001, FKBP12 associates tightly with the skeletal muscle type 1 ryanodine receptor, but not with other intracellular calcium release channels, FEBS Lett., 505, 97, 10.1016/S0014-5793(01)02787-9

Gaburjakova, 2001, FKBP12 binding modulates ryanodine receptor channel gating, J. Biol. Chem., 276, 16931, 10.1074/jbc.M100856200

Timerman, 1993, The calcium release channel of sarcoplasmic reticulum is modulated by FK-506-binding protein. Dissociation and reconstitution of FKBP-12 to the calcium release channel of skeletal muscle sarcoplasmic reticulum, J. Biol. Chem., 268, 22992, 10.1016/S0021-9258(19)49416-7

Mayrleitner, 1994, The calcium release channel of sarcoplasmic reticulum is modulated by FK-506 binding protein: effect of FKBP-12 on single channel activity of the skeletal muscle ryanodine receptor, Cell Calcium, 15, 99, 10.1016/0143-4160(94)90048-5

Brillantes, 1994, Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein, Cell, 77, 513, 10.1016/0092-8674(94)90214-3

Bultynck, 2001, Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor, Biochem. J., 354, 413, 10.1042/bj3540413

Bultynck, 2001, The conserved sites for the FK506-binding proteins in ryanodine receptors and inositol 1,4,5-trisphosphate receptors are structurally and functionally different, J. Biol. Chem., 276, 47715, 10.1074/jbc.M106573200

Jeyakumar, 2001, FKBP binding characteristics of cardiac microsomes from diverse vertebrates, Biochem. Biophys. Res. Commun., 281, 979, 10.1006/bbrc.2001.4444

Murayama, 1999, Further characterization of the type 3 ryanodine receptor (RyR3) purified from rabbit diaphragm, J. Biol. Chem., 274, 17297, 10.1074/jbc.274.24.17297

Shou, 1998, Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12, Nature, 391, 489, 10.1038/35146

Van Acker, 2004, The 12kDa FK506-binding protein, FKBP12, modulates the Ca2+-flux properties of the type-3 ryanodine receptor, J. Cell Sci., 117, 1129, 10.1242/jcs.00948

Kaftan, 1996, Effects of rapamycin on ryanodine receptor/Ca2+-release channels from cardiac muscle, Circ. Res., 78, 990, 10.1161/01.RES.78.6.990

Ahern, 1997, Subconductance states in single-channel activity of skeletal muscle ryanodine receptors after removal of FKBP12, Biophys. J., 72, 146, 10.1016/S0006-3495(97)78654-5

Bielefeldt, 1997, Tacrolimus (FK506) modulates calcium release and contractility of intestinal smooth muscle, Cell Calcium, 22, 507, 10.1016/S0143-4160(97)90078-6

Zheng, 2004, Role of FKBP12,6 in hypoxia- and norepinephrine-induced Ca2+ release and contraction in pulmonary artery myocytes, Cell Calcium, 35, 345, 10.1016/j.ceca.2003.09.006

Tang, 2002, Role of FKBP12,6 in cADPR-induced activation of reconstituted ryanodine receptors from arterial smooth muscle, Am. J. Physiol. Heart Circ. Physiol., 282, H1304, 10.1152/ajpheart.00843.2001

Wang, 2004, FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells, Am. J. Physiol. Cell Physiol., 286, C538, 10.1152/ajpcell.00106.2003

Chen, 2004, Protein methylation activates reconstituted ryanodine receptor-Ca release channels from coronary artery myocytes, J. Vasc. Res., 41, 229, 10.1159/000078178

MacMillan, 2005, In smooth muscle, FK506-binding protein modulates IP3 receptor-evoked Ca2+ release by mTOR and calcineurin, J. Cell Sci., 118, 5443, 10.1242/jcs.02657

Ji, 2004, RYR2 proteins contribute to the formation of Ca2+ sparks in smooth muscle, J. Gen. Physiol., 123, 377, 10.1085/jgp.200308999

Weidelt, 2000, Augmentation of SR Ca2+ release by rapamycin and FK506 causes K+-channel activation and membrane hyperpolarization in bladder smooth muscle, Br. J. Pharmacol., 129, 1293, 10.1038/sj.bjp.0703223

Yasutsune, 1999, Vasorelaxation and inhibition of the voltage-operated Ca2+ channels by FK506 in the porcine coronary artery, Br. J. Pharmacol., 126, 717, 10.1038/sj.bjp.0702339

Barg, 1997, Different interactions of cardiac and skeletal muscle ryanodine receptors with FK-506 binding protein isoforms, Am. J. Physiol., 272, C1726, 10.1152/ajpcell.1997.272.5.C1726

Liu, 1991, Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes, Cell, 66, 807, 10.1016/0092-8674(91)90124-H

Liu, 1992, Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity, Biochemistry, 31, 3896, 10.1021/bi00131a002

Cameron, 1995, Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux, Cell, 83, 463, 10.1016/0092-8674(95)90124-8

Shin, 2002, Ca2+-dependent interaction between FKBP12 and calcineurin regulates activity of the Ca2+ release channel in skeletal muscle, Biophys. J., 83, 2539, 10.1016/S0006-3495(02)75265-X

Bandyopadhyay, 2000, Calcineurin regulates ryanodine receptor/Ca2+-release channels in rat heart, Biochem. J., 352, 61, 10.1042/bj3520061

Marks, 1996, Cellular functions of immunophilins, Physiol. Rev., 76, 631, 10.1152/physrev.1996.76.3.631

Heitman, 1991, Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast, Science, 253, 905, 10.1126/science.1715094

Panwalkar, 2004, Mammalian target of rapamycin inhibition as therapy for hematologic malignancies, Cancer, 100, 657, 10.1002/cncr.20026

Brown, 1995, Control of p70 s6 kinase by kinase activity of FRAP in vivo, Nature, 377, 441, 10.1038/377441a0

Law, 2005, Rapamycin: an anti-cancer immunosuppressant?, Crit. Rev. Oncol. Hematol., 56, 47, 10.1016/j.critrevonc.2004.09.009

Sun, 2005, Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition, Cancer Res., 65, 7052, 10.1158/0008-5472.CAN-05-0917

Fischereder, 2004, New immunosuppressive strategies in renal transplant recipients, J. Nephrol., 17, 9

Karatas, 2005, Sirolimus as primary immunosuppression agent in kidney transplant recipients: Akdeniz University experience, Transplant. Proc., 37, 3006, 10.1016/j.transproceed.2005.08.021

McCarron, 2004, Origin and mechanisms of Ca2+ waves in smooth muscle as revealed by localized photolysis of caged inositol 1,4,5-trisphosphate, J. Biol. Chem., 279, 8417, 10.1074/jbc.M311797200

MacMillan, 2005, IP3-mediated Ca2+ increases do not involve the ryanodine receptor, but ryanodine receptor antagonists reduce IP3-mediated Ca2+ increases in guinea-pig colonic smooth muscle cells, J. Physiol., 569, 533, 10.1113/jphysiol.2005.096529

McCarron, 1999, Mitochondrial regulation of the cytosolic Ca2+ concentration and the InsP3-sensitive Ca2+ store in guinea-pig colonic smooth muscle, J. Physiol., 516, 149, 10.1111/j.1469-7793.1999.149aa.x

Dargan, 2002, Modulation of type-1 Ins(1,4,5)P3 receptor channels by the FK506-binding protein, FKBP12, Biochem. J., 361, 401, 10.1042/bj3610401

George, 2003, In situ modulation of the human cardiac ryanodine receptor (hRyR2) by FKBP12.6, Biochem. J., 370, 579, 10.1042/bj20021433

Currie, 1999, Enhanced phosphorylation of phospholamban and downregulation of sarco/endoplasmic reticulum Ca2+ ATPase type 2 (SERCA 2) in cardiac sarcoplasmic reticulum from rabbits with heart failure, Cardiovasc. Res., 41, 135, 10.1016/S0008-6363(98)00241-7

Rusnak, 2000, Calcineurin: form and function, Physiol. Rev., 80, 1483, 10.1152/physrev.2000.80.4.1483

Vallot, 2000, Intracellular Ca2+ handling in vascular smooth muscle cells is affected by proliferation, Arterioscler. Thromb. Vasc. Biol., 20, 1225, 10.1161/01.ATV.20.5.1225

Wagenknecht, 1996, Cryoelectron microscopy resolves FK506-binding protein sites on the skeletal muscle ryanodine receptor, Biophys. J., 70, 1709, 10.1016/S0006-3495(96)79733-3