FIRST EPISODE PSYCHOSIS: EARLY INTERVENTION STRATEGIES WITH SECOND‐GENERATION ANTIPSYCHOTIC MEDICATIONS

International Journal of Clinical Practice - Tập 57 Số 6 - Trang 513-518 - 2003
KE Bryden1,2, David M. Gardner1,2, LC Kopala1,2
1Department of Psychiatry, Dalhousie University, Halifax
2Research and Community Education Group, Nova Scotia Hospital, Dartmouth, Nova Scotia, Canada

Tóm tắt

SUMMARYSchizophrenia is a debilitating chronic illness that has its onset in adolescence or the early years of adulthood. The benefit of early diagnosis and treatment has been acknowledged for decades, although facilitating the early identification of patients with schizophrenia remains a challenge. Research has demonstrated that many individuals are living with the symptoms of Psychosis for prolonged periods in the community, and family physicians are well positioned to identify such patients Community education is an important strategy, in that it increases the general awareness of psychotic illness and lessens the stigma of mental illness, eventually encouraging individuals to seek help. We review here some of the evidence indicating the benefit of early treatment, and describe the strategies to assist in the identification of patients with a first episode of schizophrenia and key treatment modalities available. Ultimately, there is a need for comprehensive, accessible healthcare including medications that have minimal side‐effects and are effective.

Từ khóa


Tài liệu tham khảo

10.1093/schbul/17.2.325

10.1016/S0140-6736(59)91134-1

10.1001/archpsyc.59.10.921

10.1016/S0920-9964(02)00167-6

10.1176/ajp.149.9.1183

10.1001/archpsyc.1993.01820170047006

10.1176/ajp.156.4.544

10.1176/ps.46.11.1166

10.1093/schbul/21.4.527

10.1080/00332747.1992.11024572

McGorry PD, 1995, Handbook of preventive psychiatry, 492

10.1093/schbul/22.2.305

10.1192/bjp.164.4.487

10.1176/ajp.152.7.967

10.1016/S0010-440X(95)90068-3

Clouston TS., 1891, The neuroses of development

Clouston TS., 1892, Clinical lectures on mental diseases

10.1016/0920-9964(90)90197-F

10.1192/bjp.162.1.80

10.1192/bjp.165.4.466

10.1016/S0193-953X(18)30631-2

10.1093/schbul/13.3.477

10.1001/archpsyc.1992.01820030053007

10.1001/archpsyc.1988.01800260109013

10.1136/bmj.302.6792.1576

10.1016/0920-9964(94)00017-3

10.1001/archpsyc.1978.01770260038003

10.1136/bmj.309.6956.699

10.1176/ajp.139.5.640

10.1093/schbul/9.4.571

10.1176/ajp.144.5.666

10.1176/ajp.147.8.1052

10.1176/ajp.152.2.191

10.1093/schbul/22.2.353

10.1001/archpsyc.58.1.33

10.1176/ajp.150.9.1343

10.1176/ajp.152.12.1724

10.1016/0006-3223(95)00500-5

10.1111/j.1600-0447.1996.tb05943.x

Kopala LC, 1998, Risperidone in first episode schizophrenia: improvement in symptoms and pre‐existing extrapyramidal signs, Int J Psych Clin Pract, 2

10.1001/archpsyc.1991.01810320063009

10.1136/bmj.301.6756.837

10.1001/archpsyc.1991.01810280049007

10.1176/ajp.152.8.1210

10.1007/s002130050277

10.1097/00004714-199708000-00011

10.1097/00004714-199710000-00010

10.1001/archpsyc.1997.01830180067009

10.1016/S0920-9964(98)00040-1

10.1176/appi.ajp.159.1.103

10.1093/schbul/22.2.283

10.1016/S0193-953X(18)30644-0

Rhode A, 1988, Current research on suicide and parasuicide, 78

10.1111/j.1600-0447.1990.tb05472.x

10.1176/ajp.149.3.394

10.1176/ajp.150.1.108

10.1176/ajp.154.2.199

10.1176/ajp.151.12.1744

10.1056/NEJM199103143241107

10.1016/0024-3205(95)02037-J

10.1097/00004714-199302000-00004

10.1176/ajp.151.6.825

10.1016/S0925-4927(99)00032-3

10.1016/S0893-133X(96)00218-7

10.1176/appi.ajp.159.2.255

10.1016/S0925-4927(01)00085-3

10.1176/ajp.154.4.457

10.1034/j.1600-0447.2002.2c257a.x

10.1345/aph.19327

10.1345/aph.10280

10.1097/00004714-199604000-00008

10.1016/S0006-3223(97)00190-X

Sciolla A, 1998, Use of antipsychotics in the elderly, Int J Psych Clin Pract, 2

10.1080/13651500050517849

McEvoy JP, 1999, The Expert Consensus Guideline Series: treatment of schizophrenia 1999, J Clin Psychiatry, 60, 1