Extra-pleural pneumonectomy versus no extra-pleural pneumonectomy for patients with malignant pleural mesothelioma: clinical outcomes of the Mesothelioma and Radical Surgery (MARS) randomised feasibility study

The Lancet Oncology - Tập 12 Số 8 - Trang 763-772 - 2011
Tom Treasure1, Loı̈c Lang-Lazdunski2, David Waller3, Judith M. Bliss4, Carol Tan5, James Entwisle6, M. Snee7, Mary Claire O’Brien8, Gill Thomas9, Suresh Senan10, Kenneth J. O’Byrne11, Lucy Kilburn4, James Spicer12, David Landau12, John Edwards13, Gill Coombes4, Liz Darlison14, Julian Peto15
1Department of Mathematics, Clinical Operational Research Unit, University College London, London, UK.
2Thoracic Surgery, Guy's and St Thomas' NHS Foundation Trust, London, UK
3Department of Thoracic Surgery, Glenfield Hospital, Leicester, UK
4Clinical Trials & Statistics Unit, Section of Clinical Trials, Institute of Cancer Research, Sutton, UK
5Thoracic Surgery, St George's Hospital, London, UK
6Radiology, Wellington Hospital, Wellington, New Zealand
7St James' Institute of Oncology, St James's University Hospital, Leeds, UK
8Medical Oncology, Royal Marsden NHS Foundation Trust, Sutton, London, UK
9Oncology, Leicester Royal Infirmary, Leicester, UK
10Department of Radiation Oncology, VU University Medical Centre, Amsterdam, Netherlands.
11Oncology, St. James’s Hospital and Trinity College Dublin, Ireland
12Oncology, Guy’s & St Thomas’ NHS Foundation Trust, London, UK
13Thoracic Surgery, Northern General Hospital, Sheffield, UK
14Department of Nursing, Glenfield Hospital, Leicester, UK
15Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK

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Peto, 1995, Continuing increase in mesothelioma mortality in Britain, Lancet, 345, 535, 10.1016/S0140-6736(95)90462-X

Hodgson, 2005, The expected burden of mesothelioma mortality in Great Britain from 2002 to 2050, Br J Cancer, 92, 587, 10.1038/sj.bjc.6602307

Peto, 1999, The European mesothelioma epidemic, Br J Cancer, 79, 666, 10.1038/sj.bjc.6690105

Sugarbaker, 1999, Resection margins, extrapleural nodal status, and cell type determine postoperative long-term survival in trimodality therapy of malignant pleural mesothelioma: results in 183 patients, J Thorac Cardiovasc Surg, 117, 54, 10.1016/S0022-5223(99)70469-1

Rusch, 2001, A phase II trial of surgical resection and adjuvant high-dose hemithoracic radiation for malignant pleural mesothelioma, J Thorac Cardiovasc Surg, 22, 788, 10.1067/mtc.2001.116560

Aziz, 2002, The management of malignant pleural mesothelioma; single centre experience in 10 years, Eur J Cardiothorac Surg, 22, 298, 10.1016/S1010-7940(02)00273-7

Stewart, 2004, The effect of extent of local resection on patterns of disease progression in malignant pleural mesothelioma, Ann Thorac Surg, 78, 245, 10.1016/j.athoracsur.2004.01.034

Treasure, 2004, Pleural mesothelioma: little evidence, still time to do trials, Lancet, 364, 1183, 10.1016/S0140-6736(04)17108-0

Treasure, 2004, Radical surgery for mesothelioma, BMJ, 328, 237, 10.1136/bmj.328.7434.237

Tan, 2002, Survival in surgically diagnosed patients with malignant mesothelioma in current practice, Thorax, 57, 36

Treasure, 2009, The Mesothelioma and Radical Surgery randomized controlled trial: the MARS feasibility study, J Thorac Oncol, 4, 1254, 10.1097/JTO.0b013e3181ae26ae

2001, BTS guidelines: guidelines on the selection of patients with lung cancer for surgery, Thorax, 56, 89, 10.1136/thorax.56.2.89

Rusch, 1995, A proposed new international TNM staging system for malignant pleural mesothelioma. From the International Mesothelioma Interest Group, Chest, 108, 1122, 10.1378/chest.108.4.1122

Cao, 2010, A systematic review of extrapleural pneumonectomy for malignant pleural mesothelioma, J Thorac Oncol, 5, 1692, 10.1097/JTO.0b013e3181ed0489

Weder, 2007, Multicenter trial of neo-adjuvant chemotherapy followed by extrapleural pneumonectomy in malignant pleural mesothelioma, Ann Oncol, 18, 1196, 10.1093/annonc/mdm093

Rea, 2007, Induction chemotherapy, extrapleural pneumonectomy (EPP) and adjuvant hemi-thoracic radiation in malignant pleural mesothelioma (MPM): feasibility and results, Lung Cancer, 57, 89, 10.1016/j.lungcan.2007.02.004

Krug, 2009, Multicenter phase II trial of neoadjuvant pemetrexed plus cisplatin followed by extrapleural pneumonectomy and radiation for malignant pleural mesothelioma, J Clin Oncol, 27, 3007, 10.1200/JCO.2008.20.3943

De Perrot, 2009, Trimodality therapy with induction chemotherapy followed by extrapleural pneumonectomy and adjuvant high-dose hemithoracic radiation for malignant pleural mesothelioma, J Clin Oncol, 27, 1413, 10.1200/JCO.2008.17.5604

Van Schil, 2010, Trimodality therapy for malignant pleural mesothelioma: results from an EORTC phase II multicentre trial, Eur Respir J, 36, 1362, 10.1183/09031936.00039510

Sugarbaker, 2004, Prevention, early detection, and management of complications after 328 consecutive extrapleural pneumonectomies, J Thorac Cardiovasc Surg, 128, 138, 10.1016/j.jtcvs.2004.02.021

Opitz, 2006, Incidence and management of complications after neoadjuvant chemotherapy followed by extrapleural pneumonectomy for malignant pleural mesothelioma, Eur J Cardiothorac Surg, 29, 579, 10.1016/j.ejcts.2006.01.015

Flores, 2008, Extrapleural pneumonectomy versus pleurectomy/decortication in the surgical management of malignant pleural mesothelioma: results in 663 patients, J Thorac Cardiovasc Surg, 135, 620, 10.1016/j.jtcvs.2007.10.054

Rice, 2007, Outcomes after extrapleural pneumonectomy and intensity-modulated radiation therapy for malignant pleural mesothelioma, Ann Thorac Surg, 84, 1685, 10.1016/j.athoracsur.2007.04.076

Tilleman, 2009, Extrapleural pneumonectomy followed by intracavitary intraoperative hyperthermic cisplatin with pharmacologic cytoprotection for treatment of malignant pleural mesothelioma: a phase II prospective study, J Thorac Cardiovasc Surg, 138, 405, 10.1016/j.jtcvs.2009.02.046

Flores, 2007, Prognostic factors in the treatment of malignant pleural mesothelioma at a large tertiary referral center, J Thorac Oncol, 2, 957, 10.1097/JTO.0b013e31815608d9