Expression of the human herpesvirus 6A latency-associated transcript U94A impairs cytoskeletal functions in human neural cells
Tài liệu tham khảo
Ablashi, 2014, Classification of HHV-6A and HHV-6B as distinct viruses, Arch. Virol., 159, 863, 10.1007/s00705-013-1902-5
Agut, 2015, Laboratory and clinical aspects of human herpesvirus 6 infections, Clin. Microbiol. Rev., 28, 313, 10.1128/CMR.00122-14
Ahlqvist, 2005, Differential tropism of human herpesvirus 6 (HHV-6) variants and induction of latency by HHV-6A in oligodendrocytes, J Neurovirol, 11, 384, 10.1080/13550280591002379
Albright, 1998, The effect of human herpesvirus-6 (HHV-6) on cultured human neural cells: oligodendrocytes and microglia, J Neurovirol, 4, 486, 10.3109/13550289809113493
Amann, 2001, The Arp2/3 complex nucleates actin filament branches from the sides of pre-existing filaments, Nat. Cell Biol., 3, 306, 10.1038/35060104
Arbuckle, 2010, The latent human herpesvirus-6A genome specifically integrates in telomeres of human chromosomes in vivo and in vitro, Proc. Natl. Acad. Sci. U. S. A., 107, 5563, 10.1073/pnas.0913586107
Arlotta, 2005, Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo, Neuron, 45, 207, 10.1016/j.neuron.2004.12.036
Bacon, 2007, N-WASP regulates extension of filopodia and processes by oligodendrocyte progenitors, oligodendrocytes, and schwann cells-implications for axon ensheathment at myelination, Glia, 55, 844, 10.1002/glia.20505
Basu, 2018, The role of actin cytoskeleton in dendritic spines in the maintenance of long-term memory, Front. Mol. Neurosci., 11, 143, 10.3389/fnmol.2018.00143
Benilova, 2012, The toxic abeta oligomer and Alzheimer's disease: an emperor in need of clothes, Nat. Neurosci., 15, 349, 10.1038/nn.3028
Bera, 2020, AP-2 reduces amyloidogenesis by promoting BACE1 trafficking and degradation in neurons, EMBO Rep., 21, 10.15252/embr.201947954
Bodaleo, 2016, The presynaptic microtubule cytoskeleton in physiological and pathological conditions: lessons from drosophila fragile X syndrome and hereditary spastic paraplegias, Front. Mol. Neurosci., 9, 60, 10.3389/fnmol.2016.00060
Boggs, 2008, Myelin glycosphingolipids, galactosylceramide and sulfatide, participate in carbohydrate-carbohydrate interactions between apposed membranes and may form glycosynapses between oligodendrocyte and/or myelin membranes, Biochim. Biophys. Acta, 1780, 445, 10.1016/j.bbagen.2007.10.015
Boyd, 2013, Insufficient OPC migration into demyelinated lesions is a cause of poor remyelination in MS and mouse models, Acta Neuropathol., 125, 841, 10.1007/s00401-013-1112-y
Britanova, 2008, Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex, Neuron, 57, 378, 10.1016/j.neuron.2007.12.028
Bulfone, 1995, T-brain-1: a homolog of brachyury whose expression defines molecularly distinct domains within the cerebral cortex, Neuron, 15, 63, 10.1016/0896-6273(95)90065-9
Campbell, 2017, Expression of the human herpesvirus 6A latency-associated transcript U94A disrupts human oligodendrocyte progenitor migration, Sci. Rep., 7, 3978, 10.1038/s41598-017-04432-y
Campioni, 2017, Detection of inherited chromosomally integrated HHV-6 (ciHHV-6) in a marker chromosome, Eur. J. Haematol., June 98, 635, 10.1111/ejh.12872
Carbone, 2014, Herpes virus in Alzheimer's disease: relation to progression of the disease, Neurobiol. Aging, 35, 122, 10.1016/j.neurobiolaging.2013.06.024
Carson, 1997, Translocation of myelin basic protein mRNA in oligodendrocytes requires microtubules and kinesin, Cell Motil. Cytoskeleton, 38, 318, 10.1002/(SICI)1097-0169(1997)38:4<318::AID-CM2>3.0.CO;2-#
Caruso, 2009, U94 of human herpesvirus 6 inhibits in vitro angiogenesis and lymphangiogenesis, Proc. Natl. Acad. Sci. U. S. A., 106, 20446, 10.1073/pnas.0905535106
Caselli, 2006, Human herpesvirus 6 (HHV-6) U94/REP protein inhibits betaherpesvirus replication, Virology, 346, 402, 10.1016/j.virol.2005.11.018
Caselli, 2020, The U94 Gene of human herpesvirus 6: a narrative review of its role and potential functions, Cells, 9, 10.3390/cells9122608
Casiraghi, 2012, Gammaherpesvirus latency accentuates EAE pathogenesis: relevance to epstein-barr virus and multiple sclerosis, PLoS Pathog., 8, 10.1371/journal.ppat.1002715
de Castro, 2005, The molecular orchestra of the migration of oligodendrocyte precursors during development, Brain Res. Brain Res. Rev., 49, 227, 10.1016/j.brainresrev.2004.12.034
Chen, 2014, The WAVE regulatory complex links diverse receptors to the actin cytoskeleton, Cell, 156, 195, 10.1016/j.cell.2013.11.048
Chklovskii, 2004, Synaptic connectivity and neuronal morphology: two sides of the same coin, Neuron, 43, 609
Cifelli, 2020, Benzothiazole amphiphiles promote RasGRF1-associated dendritic spine formation in human stem cell-derived neurons, FEBS Open Bio, 10, 386, 10.1002/2211-5463.12788
Cochran, 2014, The dendritic hypothesis for Alzheimer's disease pathophysiology, Brain Res. Bull., 103, 18, 10.1016/j.brainresbull.2013.12.004
Cunniffe, 2021, Promoting remyelination in multiple sclerosis, J. Neurol., 268, 30, 10.1007/s00415-019-09421-x
Daibata, 1999, Inheritance of chromosomally integrated human herpesvirus 6 DNA, Blood, 94, 1545, 10.1182/blood.V94.5.1545.417a25_1545_1549
Dietrich, 2004, Infection with an endemic human herpesvirus disrupts critical glial precursor cell properties, J. Neurosci., 24, 4875, 10.1523/JNEUROSCI.5584-03.2004
Dominguez, 2013, POU-III transcription factors (Brn1, Brn2, and Oct6) influence neurogenesis, molecular identity, and migratory destination of upper-layer cells of the cerebral cortex, Cereb. Cortex, 23, 2632, 10.1093/cercor/bhs252
Donati, 2005, Variant-specific tropism of human herpesvirus 6 in human astrocytes, J. Virol., 79, 9439, 10.1128/JVI.79.15.9439-9448.2005
Fox, 1990, Human herpesvirus 6 in salivary glands, Lancet, 336, 590, 10.1016/0140-6736(90)93392-3
Francis, 1999, Doublecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons, Neuron, 23, 247, 10.1016/S0896-6273(00)80777-1
Fule Robles, 2014, Human herpesvirus types 6 and 7 infection in pediatric hematopoietic stem cell transplant recipients, Ann Transplant, 19, 269, 10.12659/AOT.889995
Galiano, 2006, Myelin basic protein functions as a microtubule stabilizing protein in differentiated oligodendrocytes, J. Neurosci. Res., 84, 534, 10.1002/jnr.20960
Gardell, 2006, Apoptotic effects of human herpesvirus-6A on glia and neurons as potential triggers for central nervous system autoimmunity, J. Clin. Virol., 37, S11, 10.1016/S1386-6532(06)70005-1
Gravel, 2017, Inherited chromosomally integrated human herpesvirus 6 and breast cancer, Cancer Epidemiol. Biomark. Prev., 26, 425, 10.1158/1055-9965.EPI-16-0735
Gravel, 2017, Cell culture systems to study human herpesvirus 6A/B chromosomal integration, J. Virol., 91, 10.1128/JVI.00437-17
Hadziselimovic, 2014, Forgetting is regulated via Musashi-mediated translational control of the Arp2/3 complex, Cell, 156, 1153, 10.1016/j.cell.2014.01.054
Hall, 1998, Persistence of human herpesvirus 6 according to site and variant: possible greater neurotropism of variant a, Clin. Infect. Dis., 26, 132, 10.1086/516280
Harris, 2015, Herpes simplex virus type 1 and other pathogens are key causative factors in sporadic Alzheimer's disease, J. Alzheimers Dis., 48, 319, 10.3233/JAD-142853
Herbert, 2017, Dynein/dynactin is necessary for anterograde transport of mbp mRNA in oligodendrocytes and for myelination in vivo, Proc. Natl. Acad. Sci. U. S. A., 114, E9153, 10.1073/pnas.1711088114
Hlushchenko, 2019, Chemical LTD, but not LTP, induces transient accumulation of gelsolin in dendritic spines, Biol. Chem., 400, 1129, 10.1515/hsz-2019-0110
Hogestyn, 2018, Contributions of neurotropic human herpesviruses herpes simplex virus 1 and human herpesvirus 6 to neurodegenerative disease pathology, Neural Regen. Res., 13, 211, 10.4103/1673-5374.226380
Honda, 2016, The modeling of Alzheimer's disease by the overexpression of mutant presenilin 1 in human embryonic stem cells, Biochem. Biophys. Res. Commun., 469, 587, 10.1016/j.bbrc.2015.12.025
Hoover, 2010, Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration, Neuron, 68, 1067, 10.1016/j.neuron.2010.11.030
Hu, 2014, Calcium influx and postsynaptic proteins coordinate the dendritic filopodium-spine transition, Dev Neurobiol, 74, 1011, 10.1002/dneu.22181
Huang, 2015, Apolipoprotein 4 may increase viral load and seizure frequency in mesial temporal lobe epilepsy patients with positive human herpes virus 6B, Neurosci. Lett., 593, 29, 10.1016/j.neulet.2014.12.063
Hubert, 2011, Unconventional actin conformations localize on intermediate filaments in mitosis, Biochem. Biophys. Res. Commun., 406, 101, 10.1016/j.bbrc.2011.02.002
Itzhaki, 2014, Herpes simplex virus type 1 and Alzheimer's disease: increasing evidence for a major role of the virus, Front. Aging Neurosci., 6, 202, 10.3389/fnagi.2014.00202
Jack, 2016, Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study, Lancet Neurol., 15, 56, 10.1016/S1474-4422(15)00323-3
Janz, 1999, Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I, Neuron, 24, 687, 10.1016/S0896-6273(00)81122-8
Jarrett, 1990, Detection of human herpesvirus-6 DNA in peripheral blood and saliva, J. Med. Virol., 32, 73, 10.1002/jmv.1890320113
Kang, 2012, Persistent infection of a gammaherpesvirus in the central nervous system, Virology, 423, 23, 10.1016/j.virol.2011.11.012
Kaspersen, 2012, Human herpesvirus-6A/B binds to spermatozoa acrosome and is the most prevalent herpesvirus in semen from sperm donors, PLoS One, 7, 10.1371/journal.pone.0048810
Kim, 2006, WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination, J. Neurosci., 26, 5849, 10.1523/JNEUROSCI.4921-05.2006
Koskinen, 2014, Myosin IIb controls actin dynamics underlying the dendritic spine maturation, Mol. Cell. Neurosci., 61, 56, 10.1016/j.mcn.2014.05.008
Koyanagi, 2008, Inhibition of the Rho/ROCK pathway reduces apoptosis during transplantation of embryonic stem cell-derived neural precursors, J. Neurosci. Res., 86, 270, 10.1002/jnr.21502
Lacor, 2007, Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease, J. Neurosci., 27, 796, 10.1523/JNEUROSCI.3501-06.2007
Larner, 2006, Neuroinhibitory molecules in Alzheimer's disease, J. Alzheimers Dis., 10, 75, 10.3233/JAD-2006-10111
Lin, 2018, APOE4 causes widespread molecular and cellular alterations associated with Alzheimer's disease phenotypes in human iPSC-derived brain cell types, Neuron, 98, 1141, 10.1016/j.neuron.2018.05.008
Liu, 2003, Oligodendrocyte process outgrowth in vitro is modulated by epigenetic regulation of cytoskeletal severing proteins, Glia, 44, 264, 10.1002/glia.10290
Liu, 2018, Detection of EBV and HHV6 in the brain tissue of patients with Rasmussen's encephalitis, Virol. Sin., 33, 402, 10.1007/s12250-018-0063-9
Luppi, 1994, Human herpesvirus 6 infection in normal human brain tissue, J. Infect. Dis., 169, 943, 10.1093/infdis/169.4.943
Machesky, 1998, Scar1 and the related wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex, Curr. Biol., 8, 1347, 10.1016/S0960-9822(98)00015-3
Mainen, 1996, Influence of dendritic structure on firing pattern in model neocortical neurons, Nature, 382, 363, 10.1038/382363a0
Masliah, 2001, Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease, Neurology, 56, 127, 10.1212/WNL.56.1.127
Mazur, 2016, Gelsolin interacts with LamR, hnRNP U, nestin, Arp3 and beta-tubulin in human melanoma cells as revealed by immunoprecipitation and mass spectrometry, Eur. J. Cell Biol., 95, 26, 10.1016/j.ejcb.2015.11.001
Menendez, 2016, Resident T cells are unable to control herpes simplex Virus-1 activity in the brain ependymal region during latency, J. Immunol., 197, 1262, 10.4049/jimmunol.1600207
Menon, 2018, Recent advances in branching mechanisms underlying neuronal morphogenesis, F1000Res, 7, 10.12688/f1000research.16038.1
Miyahara, 2018, Unique cell tropism of HHV-6B in an infantile autopsy case of primary HHV-6B encephalitis, Neuropathology, 38, 400, 10.1111/neup.12462
Mock, 2006, Characterization of specific HHV-6 and cell cycle genes implicated in virus-mediated G1/S cell-cycle arrest of glial precursors, Retrovirology, 3, S65, 10.1186/1742-4690-3-S1-S65
Morissette, 2010, Herpesviruses and chromosomal integration, J. Virol., 84, 12100, 10.1128/JVI.01169-10
Mullins, 2000, Actin assembly mediated by Arp2/3 complex and WASP family proteins, Methods Enzymol., 325, 214, 10.1016/S0076-6879(00)25445-1
Munoz-Lasso, 2020, Much more than a scaffold: cytoskeletal proteins in neurological disorders, Cells, 9, 10.3390/cells9020358
Muratore, 2017, Cell-type dependent Alzheimer's disease phenotypes: probing the biology of selective neuronal vulnerability, Stem Cell Reports, 9, 1868, 10.1016/j.stemcr.2017.10.015
Nawaz, 2015, Actin filament turnover drives leading edge growth during myelin sheath formation in the central nervous system, Dev. Cell, 34, 139, 10.1016/j.devcel.2015.05.013
Nieweg, 2015, Alzheimer's disease-related amyloid-beta induces synaptotoxicity in human iPS cell-derived neurons, Cell Death Dis., 6, 10.1038/cddis.2015.72
Nozumi, 2003, Differential localization of WAVE isoforms in filopodia and lamellipodia of the neuronal growth cone, J. Cell Sci., 116, 239, 10.1242/jcs.00233
Oakes, 2018, Lamellipodium is a myosin-independent mechanosensor, Proc. Natl. Acad. Sci. U. S. A., 115, 2646, 10.1073/pnas.1715869115
Ong, 2002, Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics, Mol. Cell. Proteomics, 1, 376, 10.1074/mcp.M200025-MCP200
Osterrieder, 2014, Herpesvirus genome integration into telomeric repeats of host cell chromosomes, Annu Rev Virol, 1, 215, 10.1146/annurev-virology-031413-085422
Pantry, 2013, Persistent human herpesvirus-6 infection in patients with an inherited form of the virus, J. Med. Virol., 85, 1940, 10.1002/jmv.23685
Pedraza, 2014, Induction of oligodendrocyte differentiation and in vitro myelination by inhibition of rho-associated kinase, ASN Neuro, 6, 10.1177/1759091414538134
Portolani, 2005, Post-mortem diagnosis of encephalitis in a 75-year-old man associated with human herpesvirus-6 variant a, J. Med. Virol., 77, 244, 10.1002/jmv.20443
Poulain, 2010, The microtubule network and neuronal morphogenesis: dynamic and coordinated orchestration through multiple players, Mol. Cell. Neurosci., 43, 15, 10.1016/j.mcn.2009.07.012
Rapp, 2000, U94, the human herpesvirus 6 homolog of the parvovirus nonstructural gene, is highly conserved among isolates and is expressed at low mRNA levels as a spliced transcript, Virology, 268, 504, 10.1006/viro.1999.0163
Readhead, 2018, Multiscale analysis of independent Alzheimer's cohorts finds disruption of molecular, genetic, and clinical networks by human herpesvirus, Neuron, 99, 64, 10.1016/j.neuron.2018.05.023
Rotola, 1998, U94 of human herpesvirus 6 is expressed in latently infected peripheral blood mononuclear cells and blocks viral gene expression in transformed lymphocytes in culture, Proc. Natl. Acad. Sci. U. S. A., 95, 13911, 10.1073/pnas.95.23.13911
Russell, 2012, Amyloid-beta acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2, PLoS One, 7, 10.1371/journal.pone.0043201
Saito, 1995, Cellular localization of human herpesvirus-6 in the brains of children with AIDS encephalopathy, J Neurovirol, 1, 30, 10.3109/13550289509111008
Scheff, 1993, Quantitative assessment of synaptic density in the entorhinal cortex in Alzheimer's disease, Ann. Neurol., 34, 356, 10.1002/ana.410340309
Sedlak, 2014, Identification of chromosomally integrated human herpesvirus 6 by droplet digital PCR, Clin. Chem., 60, 765, 10.1373/clinchem.2013.217240
Seo, 2017, Inhibition of p25/Cdk5 attenuates tauopathy in mouse and iPSC models of frontotemporal dementia, J. Neurosci., 37, 9917, 10.1523/JNEUROSCI.0621-17.2017
Serrano-Pozo, 2011, Neuropathological alterations in alzheimer disease, Cold Spring Harb Perspect Med, 1, 10.1101/cshperspect.a006189
Shao, 2017, LINGO-1 regulates oligodendrocyte differentiation through the cytoplasmic gelsolin signaling pathway, J. Neurosci., 37, 3127, 10.1523/JNEUROSCI.3722-16.2017
Sharon, 2017, Human herpesvirus 6A exhibits restrictive propagation with limited activation of the protein kinase R-eIF2alpha stress pathway, J. Virol., 91, 10.1128/JVI.02120-16
Shashikala, 2013, Fodrin in centrosomes: implication of a role of fodrin in the transport of gamma-tubulin complex in brain, PLoS One, 8, 10.1371/journal.pone.0076613
Sholl, 1953, Dendritic organization in the neurons of the visual and motor cortices of the cat, J. Anat., 87, 387
Skuja, 2017, Structural and ultrastructural alterations in human olfactory pathways and possible associations with herpesvirus 6 infection, PLoS One, 12, 10.1371/journal.pone.0170071
Sloane, 2007, WAVE1 and regulation of actin nucleation in myelination, Neuroscientist, 13, 486, 10.1177/1073858407299423
Song, 2001, Cytoskeletal reorganization during the formation of oligodendrocyte processes and branches, Mol. Cell. Neurosci., 17, 624, 10.1006/mcne.2001.0974
Spillane, 2012, Nerve growth factor-induced formation of axonal filopodia and collateral branches involves the intra-axonal synthesis of regulators of the actin-nucleating Arp2/3 complex, J. Neurosci., 32, 17671, 10.1523/JNEUROSCI.1079-12.2012
Spires-Jones, 2014, The intersection of amyloid beta and tau at synapses in Alzheimer's disease, Neuron, 82, 756, 10.1016/j.neuron.2014.05.004
Strenger, 2014, Detection of HHV-6-specific mRNA and antigens in PBMCs of individuals with chromosomally integrated HHV-6 (ciHHV-6), Clin. Microbiol. Infect., 20, 1027, 10.1111/1469-0691.12639
Suetsugu, 2003, Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration, Dev. Cell, 5, 595, 10.1016/S1534-5807(03)00297-1
Sweeney, 2015, A novel role for WAVE1 in controlling actin network growth rate and architecture, Mol. Biol. Cell, 26, 495, 10.1091/mbc.E14-10-1477
Tanaka-Taya, 2004, Human herpesvirus 6 (HHV-6) is transmitted from parent to child in an integrated form and characterization of cases with chromosomally integrated HHV-6 DNA, J. Med. Virol., 73, 465, 10.1002/jmv.20113
Tesini, 2014, Clinical impact of primary infection with roseoloviruses, Curr Opin Virol, 9, 91, 10.1016/j.coviro.2014.09.013
Turner, 2002, Characterisation of a human herpesvirus 6 variant A 'amplicon' and replication modulation by U94-rep 'latency gene', J. Virol. Methods, 105, 331, 10.1016/S0166-0934(02)00130-1
Usenovic, 2015, Internalized tau oligomers cause neurodegeneration by inducing accumulation of pathogenic tau in human neurons derived from induced pluripotent stem cells, J. Neurosci., 35, 14234, 10.1523/JNEUROSCI.1523-15.2015
Vetter, 2001, Propagation of action potentials in dendrites depends on dendritic morphology, J. Neurophysiol., 85, 926, 10.1152/jn.2001.85.2.926
Wagner, 1997, Human herpesvirus-6 (HHV-6)-associated necrotizing encephalitis in Griscelli's syndrome, J. Med. Virol., 53, 306, 10.1002/(SICI)1096-9071(199711)53:3<306::AID-JMV21>3.0.CO;2-D
Wainwright, 2001, Human herpesvirus 6 limbic encephalitis after stem cell transplantation, Ann. Neurol., 50, 612, 10.1002/ana.1251
Ward, 2005, The natural history and laboratory diagnosis of human herpesviruses-6 and -7 infections in the immunocompetent, J. Clin. Virol., 32, 183, 10.1016/j.jcv.2004.11.008
Ward, 2006, Human herpesvirus 6 chromosomal integration in immunocompetent patients results in high levels of viral DNA in blood, sera, and hair follicles, J. Clin. Microbiol., 44, 1571, 10.1128/JCM.44.4.1571-1574.2006
Westberg, 1999, Regulation of neural differentiation by normal and mutant (G654A, amyloidogenic) gelsolin, FASEB J., 13, 1621, 10.1096/fasebj.13.12.1621
Westphal, 2000, Scar/WAVE-1, a wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold, EMBO J., 19, 4589, 10.1093/emboj/19.17.4589
Wu, 2009, {beta}4 tubulin identifies a primitive cell source for oligodendrocytes in the mammalian brain, J. Neurosci., 29, 7649, 10.1523/JNEUROSCI.1027-09.2009
Wyatt, 1990, Variations in the replication and antigenic properties of human herpesvirus 6 strains, J. Infect. Dis., 162, 852, 10.1093/infdis/162.4.852
Yamazaki, 2005, A novel function of WAVE in lamellipodia: WAVE1 is required for stabilization of lamellipodial protrusions during cell spreading, Genes Cells, 10, 381, 10.1111/j.1365-2443.2005.00845.x
Yoshikawa, 2002, Latent infection of human herpesvirus 6 in astrocytoma cell line and alteration of cytokine synthesis, J. Med. Virol., 66, 497, 10.1002/jmv.2172
Zhao, 2006, Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease, Nat. Neurosci., 9, 234, 10.1038/nn1630
Zuchero, 2015, CNS myelin wrapping is driven by actin disassembly, Dev. Cell, 34, 152, 10.1016/j.devcel.2015.06.011