Expression of OTUB1 in hepatocellular carcinoma and its effects on HCC cell migration and invasion

Acta Biochimica et Biophysica Sinica - Tập 49 Số 8 - Trang 680-688 - 2017
Qinggan Ni1, Jiahui Chen2, Xia Li3, Xiaodong Xu1, Nannan Zhang1, Ang Zhou1, Bin Zhou1, Qian Lü1, Zhong Chen1
1Department of Hepatobiliary Surgery, Affiliated Hospital, Nantong University, Research Institute of Hepatobiliary Surgery of Nantong University, Nantong 226001, China
2Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
3Department of Respiratory Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China

Tóm tắt

Từ khóa


Tài liệu tham khảo

2015, Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy, Oncotarget, 6, 37511, 10.18632/oncotarget.5527

2011, Global cancer statistics, CA Cancer J Clin, 61, 69, 10.3322/caac.20107

2015, Global cancer statistics, 2012, CA Cancer J Clin, 65, 87, 10.3322/caac.21262

2010, Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008, Int J Cancer, 127, 2893, 10.1002/ijc.25516

2007, Hepatocellular carcinoma: trends of incidence and survival in Europe and the United States at the end of the 20th century, Am J Gastroenterol, 102, 1661, 10.1111/j.1572-0241.2007.01337.x

2004, Hepatocellular carcinoma: recent trends in the United States, Gastroenterology, 127, S27, 10.1053/j.gastro.2004.09.013

2008, Survival analysis of patients with transplantable recurrent hepatocellular carcinoma: implications for salvage liver transplant, Arch Surg, 143, 68, 10.1001/archsurg.2007.15

2007, PIVKA-II is a useful tumor marker for recurrent hepatocellular carcinoma after surgical resection, Oncology, 72, 52, 10.1159/000111707

2015, Recent advances in cancer therapeutics, Prog Med Chem, 54, 1, 10.1016/bs.pmch.2014.11.002

2015, Current trends and recent advances in diagnosis, therapy, and prevention of hepatocellular carcinoma, Asian Pac J Cancer Prev, 16, 3595, 10.7314/APJCP.2015.16.9.3595

2012, The ubiquitin code, Annu Rev Biochem, 81, 203, 10.1146/annurev-biochem-060310-170328

2014, Ubiquitination in disease pathogenesis and treatment, Nat Med, 20, 1242, 10.1038/nm.3739

2015, Deubiquitinating enzymes as oncotargets, Oncotarget, 6, 9657, 10.18632/oncotarget.3922

2003, Otubains: a new family of cysteine proteases in the ubiquitin pathway, EMBO Rep, 4, 517, 10.1038/sj.embor.embor824

2009, Defining the human deubiquitinating enzyme interaction landscape, Cell, 138, 389, 10.1016/j.cell.2009.04.042

2005, A genomic and functional inventory of deubiquitinating enzymes, Cell, 123, 773, 10.1016/j.cell.2005.11.007

2000, A novel superfamily of predicted cysteine proteases from eukaryotes, viruses and Chlamydia pneumoniae, Trends Biochem Sci, 25, 50, 10.1016/S0968-0004(99)01530-3

2003, A novel type of deubiquitinating enzyme, J Biol Chem, 278, 23180, 10.1074/jbc.M301863200

2016, OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance, Oncogene, 35, 1433, 10.1038/onc.2015.208

2004, Two isoforms of otubain 1 regulate T cell anergy via GRAIL, Nat Immunol, 5, 45, 10.1038/ni1017

2013, OTUB1 enhances TGFβ signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3, Nat Commun, 4, 2519, 10.1038/ncomms3519

2013, OTUB1 modulates c-IAP1 stability to regulate signalling pathways, EMBO J, 32, 1103, 10.1038/emboj.2013.62

2015, OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo, Mol Cancer, 14, 8, 10.1186/s12943-014-0280-2

2016, OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination, EMBO Mol Med, 8, 288, 10.15252/emmm.201505972

2014, OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer, Mol Cancer, 13, 258, 10.1186/1476-4598-13-258

2016, OTUB1-catalyzed deubiquitination of FOXM1 facilitates tumor progression and predicts a poor prognosis in ovarian cancer, Oncotarget, 7, 36681, 10.18632/oncotarget.9160

1993, Incidence and factors associated with intrahepatic recurrence following resection of hepatocellular carcinoma, Gastroenterology, 105, 488, 10.1016/0016-5085(93)90724-Q

1996, Recurrence of hepatocellular carcinoma after surgery, Br J Surg, 83, 1219, 10.1002/bjs.1800830913

2006, A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells, Nat Med, 12, 410, 10.1038/nm1377

2011, Risk factors, prognosis, and management of early and late intrahepatic recurrence after resection of primary clear cell carcinoma of the liver, Ann Surg Oncol, 18, 1955, 10.1245/s10434-010-1540-z

2004, High alpha-fetoprotein level correlates with high stage, early recurrence and poor prognosis of hepatocellular carcinoma: significance of hepatitis virus infection, age, p53 and beta-catenin mutations, Int J Cancer, 112, 44, 10.1002/ijc.20279

2001, Serum alpha-fetoprotein for diagnosis of hepatocellular carcinoma in patients with chronic liver disease: influence of HBsAg and anti-HCV status, J Hepatol, 34, 570, 10.1016/S0168-8278(00)00053-2

2011, Clinical utility of highly sensitive Lens culinaris agglutinin-reactive alpha-fetoprotein in hepatocellular carcinoma patients with alpha-fetoprotein <20 ng/mL, Cancer Sci, 102, 1025, 10.1111/j.1349-7006.2011.01875.x

2016, OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance, Oncogene, 35, 1433, 10.1038/onc.2015.208

2016, OTUB1 promotes tumor invasion and predicts a poor prognosis in gastric adenocarcinoma, Am J Transl Res, 8, 2234

2016, Restoring mir122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through smad-independent TGF-β pathway, Oncotarget, 7, 71309, 10.18632/oncotarget.11885

2012, TGF beta1 and related-Smads contribute to pulmonary metastasis of hepatocellular carcinoma in mice model, J Exp Clin Cancer Res, 31, 93, 10.1186/1756-9966-31-93

2011, Comparison of adiponectin concentration between pancreatic cancer and colorectal cancer, J Gastrointest Oncol, 2, 232

2010, FOXM1 confers acquired cisplatin resistance in breast cancer cells, Mol Cancer Res, 8, 24, 10.1158/1541-7786.MCR-09-0432

2013, The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment, Oncogene, 32, 4634, 10.1038/onc.2012.491

2011, ATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistance, Mol Cancer Ther, 10, 1046, 10.1158/1535-7163.MCT-11-0024

2016, OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance, Oncogene, 35, 1433, 10.1038/onc.2015.208

2016, Elevated expression of FoxM1 promotes the tumor cell proliferation in hepatocellular carcinoma, Tumour Biol, 37, 1289, 10.1007/s13277-015-3436-9

2013, OTUB1 modulates c-IAP1 stability to regulate signalling pathways, EMBO J, 32, 1103, 10.1038/emboj.2013.62

2013, OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis, Cell, 154, 169, 10.1016/j.cell.2013.05.046

2010, Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6, J Biol Chem, 285, 4291, 10.1074/jbc.M109.074971