Expression of AEG-1 and microvessel density correlates with metastasis and prognosis of oral squamous cell carcinoma

Human Pathology - Tập 45 - Trang 858-865 - 2014
Xianyin Xia1, Ruirui Du1, Lingbo Zhao1, Wenjing Sun2, Xiumei Wang1
1Department of Dentistry, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China
2Laboratory of Medical Genetics, Harbin Medical University, Harbin 150081, China

Tài liệu tham khảo

Viet, 2012, Biologic mechanisms of oral cancer pain and implications for clinical therapy, J Dent Res, 91, 447, 10.1177/0022034511424156 Cohen, 2004, The expanding role of systemic therapy in head and neck cancer, J Clin Oncol, 22, 1743, 10.1200/JCO.2004.06.147 Cooper, 2004, Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck, N Engl J Med, 350, 1937, 10.1056/NEJMoa032646 Jiang, 2010, Focal adhesion kinase serves as a marker of cervical lymph node metastasis and is a potential therapeutic target in tongue cancer, J Cancer Res Clin Oncol, 136, 1295, 10.1007/s00432-010-0780-4 Kruaysawat, 2010, Survival time and prognostic factors of oral cancer in Ubon Ratchathani Cancer Center, J Med Assoc Thai, 93, 278 Sarkar, 2009, Astrocyte elevated gene-1: far more than just a gene regulated in astrocytes, Cancer Res, 69, 8529, 10.1158/0008-5472.CAN-09-1846 Hu, 2009, The multifaceted role of MTDH/AEG-1 in cancer progression, Clin Cancer Res, 15, 5615, 10.1158/1078-0432.CCR-09-0049 Anttila, 2010, Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1, Nat Genet, 42, 869, 10.1038/ng.652 Lee, 2009, Astrocyte elevated gene-1 contributes to the pathogenesis of neuroblastoma, Oncogene, 28, 2476, 10.1038/onc.2009.93 Lee, 2008, Astrocyte elevated gene-1 activates cell survival pathways through PI3K-Akt signaling, Oncogene, 27, 1114, 10.1038/sj.onc.1210713 Sarkar, 2008, Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1, Cancer Res, 68, 1478, 10.1158/0008-5472.CAN-07-6164 Liu, 2011, Identification of novel variants of metadherin in breast cancer, PLoS One, 6, e17582, 10.1371/journal.pone.0017582 Zhou, 2012, Expression of metadherin/AEG-1 gene is positively related to orientation chemotaxis and adhesion of human hepatocellular carcinoma cell lines of different metastatic potentials, J Huazhong Univ Sci Technolog Med Sci, 32, 353, 10.1007/s11596-012-0061-3 Ash, 2008, LYRIC/AEG-1 overexpression modulates BCCIPalpha protein levels in prostate tumor cells, Biochem Biophys Res Commun, 27, 333, 10.1016/j.bbrc.2008.04.084 Zhang, 2011, Astrocyte elevated gene-1 induces breast cancer proliferation and invasion through upregulating HER2/neu expression, Chin Med J (Engl), 124, 3546 Kikuno, 2007, Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity, Oncogene, 26, 7647, 10.1038/sj.onc.1210572 Qian, 2011, MTDH/AEG-1-based DNA vaccine suppresses lung metastasis and enhances chemosensitivity to doxorubicin in breast cancer, Cancer Immunol Immunother, 60, 883, 10.1007/s00262-011-0997-3 Yoo, 2009, Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression, J Clin Invest, 119, 465, 10.1172/JCI36460 Ke, 2013, Expression characteristics of astrocyte elevated gene-1 (AEG-1) in tongue carcinoma and its correlation with poor prognosis, Cancer Epidemiol, 37, 179, 10.1016/j.canep.2012.10.007 Yao, 2005, Prognostic significance of microvessel density determined by an anti-CD105/endoglin monoclonal antibody in astrocytic tumors: comparison with an anti-CD31 monoclonal antibody, Neuropathology, 25, 201, 10.1111/j.1440-1789.2005.00632.x Miller, 1999, Elevated expression of endoglin, a component of the TGF-beta-receptor complex, correlates with proliferation of tumor endothelial cells, Int J Cancer, 81, 568, 10.1002/(SICI)1097-0215(19990517)81:4<568::AID-IJC11>3.0.CO;2-X Fonsatti, 2003, Endoglin (CD105): a powerful therapeutic target on tumor-associated angiogenetic blood vessels, Oncogene, 22, 6557, 10.1038/sj.onc.1206813 Li, 2011, Significance of AEG-1 expression in correlation with VEGF, microvessel density and clinicopathological characteristics in triple-negative breast cancer, J Surg Oncol, 103, 184, 10.1002/jso.21788 Greene, 2002, 27 Kyzas, 2004, Immunohistochemical expression of vascular endothelial growth factor correlates with positive surgical margins and recurrence in T1 and T2 squamous cell carcinoma (SCC) of the lower lip, Oral Oncol, 40, 941, 10.1016/j.oraloncology.2004.04.018 Yoo, 2011, Astrocyte elevated gene-1 (AEG-1): a multifunctional regulator of normal and abnormal physiology, Pharmacol Ther, 130, 1, 10.1016/j.pharmthera.2011.01.008 Duff, 2003, CD105 is important for angiogenesis: evidence and potential applications, FASEB J, 17, 984, 10.1096/fj.02-0634rev Mărgăritescu, 2008, Endoglin (CD105) and microvessel density in oral squamous cell carcinoma, Rom J Morphol Embryol, 49, 321