Boddy K, Jones CT, Mantell C, Ratcliffe JG, Robinson JS. Changes in plasma ACTH and corticosteroid of the maternal and fetal sheep during hypoxia. Endocrinology. 1974;94:588–591.
Akagi K, Challis JR. Relationship between blood gas values and hormonal response to acute hypoxemia in fetal sheep. Gynecol Obstet Invest. 1990;30:65–70.
Adachi K, Umezaki H, Kaushal KM, Ducsay CA. Long-term hypoxia alters ovine fetal endocrine and physiological responses to hypotension. Am J Physiol Regul Integr Comp Physiol. 2004; 287:R209–R217.
Imamura T, Umezaki H, Kaushal KM, Ducsay CA. Long-term hypoxia alters endocrine and physiologic responses to umbilical cord occlusion in the ovine fetus. J Soc Gynecol Investig. 2004;11:131–140.
Myers DA, Bell PA, Hyatt K, Mlynarczyk M, Ducsay CA. Long-term hypoxia enhances proopiomelanocortin processing in the near-term ovine fetus. Am J Physiol Regul Integr Comp Physiol. 2005;288:R1178–R1184.
Jensen EC, Gallaher BW, Breier BH, Harding JE. The effect of a chronic maternal cortisol infusion on the late-gestation fetal sheep. J Endocrinol. 2002;174:27–36.
Milley JR. Effects of increased cortisol concentration on ovine fetal leucine kinetics and protein metabolism. Am J Physiol. 1995;268:E1114–E1122.
Fowden AL, Szemere J, Hughes P, Gilmour RS, Forhead AJ. The effects of cortisol on the growth rate of the sheep fetus during late gestation. J Endocrinol. 1996;151:97–105.
Liggins GC, Fairclough RJ, Grieves SA, Kendall JZ, Knox BS. The mechanism of initiation of parturition in the ewe. Recent Prog Horm Res. 1973;29:111–159.
Liggins GC, Fairclough RJ, Grieves SA, Forster CS, Knox BS. Parturition in the sheep. Ciba Found Symp. 1977:5–30.
Challis JR, Brooks AN. Maturation and activation of hypothalamic-pituitary adrenal function in fetal sheep. Endocr Rev. 1989;10:182–204.
Yang K, Challis JR. Fetal and adult sheep adrenal cortical cells contain glucocorticoid receptors. Biochem Biophys Res Commun. 1989;162:604–611.
Darbeida H, Naaman E, Durand P. Glucocorticoid induction of the maturation of ovine fetal adrenocortical cells. Biochem Biophys Res Commun. 1987;145:999–1005.
Picard-Hagen N, Darbeida H, Durand P. Glucocorticoids enhance the cholesterol side-chain cleavage activity of ovine adrenocortical mitochondria.J Steroid Biochem Mol Biol. 1995; 55:57–65.
Yang K, Hammond GL, Challis JR. Characterization of an ovine glucocorticoid receptor cDNA and developmental changes in its mRNA levels in the fetal sheep hypothalamus, pituitary gland and adrenal. J Mol Endocrinol. 1992;8: 173–180.
Bamberger CM, Schulte HM, Chrousos GP. Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids. Endocr Rev. 1996;17:245–261.
Aranda A, Pascual A. Nuclear hormone receptors and gene expression. Physiol Rev. 2001;81:1269–1304.
Hollenberg SM, Weinberger C, Ong ES, et al. Primary structure and expression of a functional human glucocorticoid receptor cDNA. Nature. 1985;318:635–641.
Giguere V, Hollenberg SM, Rosenfeld MG, Evans RM. Functional domains of the human glucocorticoid receptor. Cell. 1986;46:645–652.
Oakley RH, Sar M, Cidlowski JA. The human glucocorticoid receptor beta isoform: expression, biochemical properties, and putative function. J Biol Chem. 1996;271:9550–9559.
Oakley RH, Jewell CM, Yudt MR, Bofetiado DM, Cidlowski JA. The dominant negative activity of the human glucocorticoid receptor beta isoform: specificity and mechanisms of action. J Biol Chem. 1999;274:27857–27866.
Hecht K, Carlstedt-Duke J, Stierna P, Gustafsson J, Bronnegard M, Wikstrom AC. Evidence that the beta-isoform of the human glucocorticoid receptor does not act as a physiologically significant repressor. J Biol Chem. 1997;272: 26659–26664.
Otto C, Reichardt HM, Schutz G. Absence of glucocorticoid receptor-beta in mice.J Biol Chem. 1997;272:26665–26668.
Yudt MR, Cidlowski JA. Molecular identification and characterization of a and b forms of the glucocorticoid receptor. Mol Endocrinol. 2001;15:1093–1103.
Lu NZ, Cidlowski JA. Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes. Mol Cell. 2005;18: 331–342.
Duma D, Jewell CM, Cidlowski JA. Multiple glucocorticoid receptor isoforms and mechanisms of post-translational modification. J Steroid Biochem Mol Biol. 2006;102:11–21.
Leonard MO, Godson C, Brady HR, Taylor CT. Potentiation of glucocorticoid activity in hypoxia through induction of the glucocorticoid receptor. J Immunol. 2005;174:2250–2257.
Inouye KE, Chan O, Yue JT, Matthews SG, Vranic M. Effects of diabetes and recurrent hypoglycemia on the regulation of the sympathoadrenal system and hypothalamo-pituitary-adrenal axis. Am J Physiol Endocrinol Metab. 2005;288:E422–E429.
Paust HJ, Loeper S, Else T, et al. Expression of the glucocorticoid receptor in the human adrenal cortex. Exp Clin Endocrinol Diabetes. 2006;114:6–10.
Condon J, Gosden C, Gardener D, et al. Expression of type 2 11beta-hydroxysteroid dehydrogenase and corticosteroid hormone receptors in early human fetal life. J Clin Endocrinol Metab. 1998;83:4490–4497.
Mlynarczyk M, Imamura T, Umezaki H, Kaushal KM, Zhang L, Ducsay CA. Long-term hypoxia changes myometrial responsiveness and oxytocin receptors in the pregnant ewe: differential effects on longitudinal versus circular smooth muscle. Biol Reprod. 2003;69:1500–1505.
Myers DA, Hyatt K, Mlynarczyk M, Bird IM, Ducsay CA. Long-term hypoxia represses the expression of key genes regulating cortisol biosynthesis in the near-term ovine fetus. Am J Physiol Regul Integr Comp Physiol. 2005;289: R1707–R1714.
Ducsay CA, Hyatt K, Mlynarczyk M, Kaushal KM, Myers DA. Long-term hypoxia increases leptin receptors and plasma leptin concentrations in the late-gestation ovine fetus. Am J Physiol Regul Integr Comp Physiol. 2006;291: R1406–R1413.
Ehrhart-Bornstein M, Hinson JP, Bornstein SR, Scherbaum WA, Vinson GP. Intraadrenal interactions in the regulation of adrenocortical steroidogenesis. Endocr Rev. 1998;19: 101–143.
Saoud CJ, Wood CE. Developmental changes and molecular weight of immunoreactive glucocorticoid receptor protein in the ovine fetal hypothalamus and pituitary. Biochem Biophys Res Commun. 1996;229:916–921.
Gupta S, Gyomorey S, Lye SJ, Gibb W, Challis JR. Effect of labor on glucocorticoid receptor (GR(Total), GRalpha, and GRbeta) proteins in ovine intrauterine tissues. J Soc Gynecol Investig. 2003;10:136–144.
Betito K, Diorio J, Meaney MJ, Boksa P. Adrenal phenylethanolamine N-methyltransferase induction in relation to glucocorticoid receptor dynamics: evidence that acute exposure to high cortisol levels is sufficient to induce the enzyme. J Neurochem. 1992;58:1853–1862.
Tai TC, Claycomb R, Her S, Bloom AK, Wong DL. Glucocorticoid responsiveness of the rat phenylethanolamine N-methyltransferase gene. Mol Pharmacol. 2002;61:1385–1392.
Ebert SN, Balt SL, Hunter JP, Gashler A, Sukhatme V, Wong DL. Egr-1 activation of rat adrenal phenylethanolamine N-methyltransferase gene. J Biol Chem. 1994;269: 20885–20898.
Wong DL, Siddall BJ, Ebert SN, Bell RA, Her S. Phenylethanolamine N-methyltransferase gene expression: synergistic activation by Egr-1, AP-2 and the glucocorticoid receptor. Brain Res Mol Brain Res. 1998;61:154–161.
Ducsay CA, Hyatt K, Mlynarczyk M, Root BK, Kaushal KM, Myers DA. Long term hypoxia modulates expression of key genes regulating adrenomedullary function in the late gestation ovine fetus. Am J Physiol Regul Integr Comp Physiol. 2007;293: R1997–R2005.
Wong DL, Tai TC, Wong-Faull DC, Claycomb R, Kvetnansky R. Genetic mechanisms for adrenergic control during stress. Ann N Y Acad Sci. 2004;1018:387–397.
Oakley RH, Webster JC, Sar M, Parker CR Jr, Cidlowski JA. Expression and subcellular distribution of the beta-isoform of the human glucocorticoid receptor. Endocrinology. 1997;138: 5028–5038.