Exploring the heterogeneity of use-dependent sodium channel inhibitor drugs. II: Drugs described by the modulated receptor hypothesis (MRH) and/or the guarded receptor hypothesis (GRH)

BMC Pharmacology - Tập 7 - Trang 1-1 - 2007
Arpad Mike1, Nora Lenkey1, Robert Karoly1, E Sylvester Vizi1
1Institute of Experimental Medicine, Budapest, Hungary

Tài liệu tham khảo

Lenkey N, Karoly R, Kiss JP, Szasz BK, Vizi ES, Mike A: The mechanism of activity-dependent sodium channel inhibition by the antidepressants fluoxetine and desipramine. Mol Pharmacol. 2006, 70: 2052-2063. 10.1124/mol.106.026419.

Hille B: Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction. J Gen Physiol. 1977, 69: 497-515. 10.1085/jgp.69.4.497.

Starmer CF, Grant AO, Strauss HC: Mechanisms of use-dependent block of sodium channels in excitable membranes by local anesthetics. Biophys J. 1984, 46: 15-27.

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BMC Pharmacology

Tập 7

1-1

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