Exploring prefrontal cortex functions in healthy humans by transcranial electrical stimulation
Tóm tắt
The prefrontal cortex is involved in a multitude of cognitive, emotional, motivational, and social processes, so exploring its specific functions is crucial for understanding human experience and behavior. Functional imaging approaches have largely contributed to the enhancement of our understanding, but might have limitations in establishing causal relationships between physiology and the related psychological and behavioral processes. Non-invasive electrical stimulation with direct or alternating currents can help to enhance our understanding with regard to specific processes, and might provide future protocols able to improve them in case of malfunctions. We review the current state of the field, and provide an outlook for future developments.
Tài liệu tham khảo
Briand LA, Gritton H, Howe WM, Young DA, Sarter M. Modulators in concert for cognition: modulator interactions in the prefrontal cortex. Prog Neurobiol 2007, 83: 69–91.
Courtin J, Bienvenu TC, Einarsson EÖ, Herry C. Medial prefrontal cortex neuronal circuits in fear behavior. Neuroscience 2013, 240: 219–242.
Diamond A. Biological and social influences on cognitive control processes dependent on prefrontal cortex. Prog Brain Res 2011, 189: 319–339.
Goto Y, Yang CR, Otani S. Functional and dysfunctional synaptic plasticity in prefrontal cortex: roles in psychiatric disorders. Biol Psychiatry 2010, 67: 199–207.
Langner R, Eickhoff SB. Sustaining attention to simple tasks: a meta-analytic review of the neural mechanisms of vigilant attention. Psychol Bull 2013, 139: 870–900.
Ray RD, Zald DH. Anatomical insights into the interaction of emotion and cognition in the prefrontal cortex. Neurosci Biobehav Rev 2012, 36: 479–501.
Lett TA, Voineskos AN, Kennedy JL, Levine B, Daskalakis ZJ. treating working memory deficits in schizophrenia: a review of the neurobiology. Biol Psychiatry 2014, 75: 361–370
Luijten M, Machielsen MW, Veltman DJ, Hester R, de Haan L, Franken IH. Systematic review of ERP and fMRI studies investigating inhibitory control and error processing in people with substance dependence and behavioural addictions. J Psychiatry Neurosci 2013, 38: 130052.
Maillet D, Rajah MN. Association between prefrontal activity and volume change in prefrontal and medial temporal lobes in aging and dementia: a review. Ageing Res Rev 2013, 12: 479–489.
Narayanan NS, Rodnitzky RL, Uc EY. Prefrontal dopamine signaling and cognitive symptoms of Parkinson’s disease. J Psychiatry Neurosci 2013, 38: 130052
Trivedi MH, Greer TL. Cognitive dysfunction in unipolar depression: implications for treatment. J Affect Disord 2014, 152–154: 19–27.
Nitsche MA, Cohen LG, Wassermann EM, Priori A, Lang N, Antal A, et al. Transcranial direct current stimulation: State of the art 2008. Brain Stimul 2008, 1: 206–223.
Nitsche MA, Paulus W. Transcranial direct current stimulation—update 2011. Restor Neurol Neurosci 2011, 29: 463–492.
Herrmann CS, Rach S, Neuling T, Strüber D. Transcranial alternating current stimulation: a review of the underlying mechanisms and modulation of cognitive processes. Front Hum Neurosci 2013, 7: 279.
Ziemann U, Paulus W, Nitsche MA, Pascual-Leone A, Byblow WD, Berardelli A, et al. Consensus: Motor cortex plasticity protocols. Brain Stimul 2008, 1: 164–182.
Nitsche MA, Paulus W. Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation. J Physiol 2000, 527: 633–639.
Nitsche MA, Paulus W. Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans. Neurology 2001, 57: 1899–1901.
Nitsche MA, Nitsche MS, Klein CC, Tergau F, Rothwell JC, Paulus W. Level of action of cathodal DC polarisation induced inhibition of the human motor cortex. Clin Neurophysiol 2003a, 114: 600–604.
Nitsche MA, Fricke K, Henschke U, Schlitterlau A, Liebetanz D, Lang N, et al. Pharmacological modulation of cortical excitability shifts induced by transcranial direct current stimulation in humans. J Physiol 2003, 553: 293–301.
Nitsche MA, Jaussi W, Liebetanz D, Lang N, Tergau F, Paulus W. Consolidation of human motor cortical neuroplasticity by D-cycloserine. Neuropsychopharmacology 2004, 29: 1573–1578.
Malenka RC, Bear MF. LTP and LTD: an embarrassment of riches. Neuron 2004, 44: 5–21.
Antal A, Boros K, Poreisz C, Chaieb L, Terney D, Paulus W. Comparatively weak after-effects of transcranial alternating current stimulation (tACS) on cortical excitability in humans. Brain Stimul 2008, 2: 97–105.
Antal A, Paulus W. Transcranial alternating current stimulation (tACS). Front Hum Neurosci 2013, 7: 317.
Ali MM, Sellers KK, Fröhlich F. Transcranial alternating current stimulation modulates large-scale cortical network activity by network resonance. J Neurosci 2013, 27: 11262–11275.
Helfrich RF, Schneider TR, Rach S, Trautmann-Lengsfeld SA, Engel AK, Herrmann CS. Entrainment of brain oscillations by transcranial alternating current stimulation. Curr Biol 2014, 24: 333–339.
Kanai R, Chaieb L, Antal A, Walsh V, Paulus W. Frequency-dependent electrical stimulation of the visual cortex. Curr Biol 2008, 18: 1839–1843.
Zaehle T, Rach S, Herrmann CS. Transcranial alternating current stimulation enhances individual alpha activity in human EEG. PLoS One 2010, 5: e13766.
Mannie ZN, Harmer CJ, Cowen PJ, Norbury R. A functional magnetic resonance imaging study of verbal working memory in young people at increased familial risk of depression. Biol Psychiatry. 2010, 67: 471–477.
Fregni F, Boggio PS, Nitsche M, Bermpohl F, Antal A, Feredoes E, et al. Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory. Exp Brain Res 2005, 166: 23–30.
Ohn SH, Park CI, Yoo WK, Ko MH, Choi KP, Kim GM, et al. Time-dependent effect of transcranial direct current stimulation on the enhancement of working memory. Neuroreport 2008, 19: 43–47.
Zaehle T, Sandmann P, Thorne JD, Jäncke L, Herrmann CS. Transcranial direct current stimulation of the prefrontal cortex modulates working memory performance: combined behavioural and electrophysiological evidence. BMC Neurosci 2011, 12: 2.
Mulquiney PG, Hoy KE, Daskalakis ZJ, Fitzgerald PB. Improving working memory: exploring the effect of transcranial random noise stimulation and transcranial direct current stimulation on the dorsolateral prefrontal cortex. Clin Neurophysiol. 2011, 122: 2384–2389.
Teo F, Hoy KE, Daskalakis ZJ, Fitzgerald PB. Investigating the role of current strength in tdcs modulation of working memory performance in healthy controls. Front Psychiatry 2011, 2: 45
Hoy KE, Emonson MR, Arnold SL, Thomson RH, Daskalakis ZJ, Fitzgerald PB. Testing the limits: Investigating the effect of tDCS dose on working memory enhancement in healthy controls. Neuropsychologia 2013, 51: 1777–1784.
Berryhill ME, Jones KT. tDCS selectively improves working memory in older adults with more education. Neurosci Lett 2012, 521: 148–151.
Kim JH, Kim DW, Chang WH, Kim YH, Kim K, Im CH. Inconsistent outcomes of transcranial direct current stimulation may originate from anatomical differences among individuals: Electric field simulation using individual MRI data. Neurosci Lett 2014, 564C: 6–10.
Meiron O, Lavidor M. Unilateral prefrontal direct current stimulation effects are modulated by working memory load and gender. Brain Stimul 2013, 6: 440–447.
Lally N, Nord CL, Walsh V, Roiser JP. Does excitatory fronto-extracerebral tDCS lead to improved working memory performance? Version 2. F1000Res. 2013, 2: 219.
Jeon SY, Han SJ. Improvement of the working memory and naming by transcranial direct current stimulation. Ann Rehabil Med 2012, 36585–36595.
Polanía R, Nitsche MA, Korman C, Batsikadze G, Paulus W. The importance of timing in segregated theta phase-coupling for cognitive performance. Curr Biol 2012a, 22: 1314–1318.
Meiron O, Lavidor M. Prefrontal oscillatory stimulation modulates access to cognitive control references in retrospective metacognitive commentary. Clin Neurophysiol 2014, 125: 77–82.
Polanía R, Paulus W, Nitsche MA. Noninvasively decoding the contents of visual working memory in the human prefrontal cortex within high-gamma oscillatory patterns. J Cogn Neurosci 2012b, 24: 304–314.
Nelson JT, McKinley RA, Golob EJ, Warm JS, Parasuraman R. Enhancing vigilance in operators with prefrontal cortex transcranial direct current stimulation (tDCS). Neuroimage 2014, 85: 909–917.
Plewnia C, Zwissler B, Längst I, Maurer B, Giel K, Krüger R. Effects of transcranial direct current stimulation (tDCS) on executive functions: influence of COMT Val/Met polymorphism. Cortex 2013, 49: 1801–1807.
Javadi AH, Walsh V. Transcranial direct current stimulation (tDCS) of the left dorsolateral prefrontal cortex modulates declarative memory. Brain Stimul 2012, 5: 231–241.
Javadi AH, Cheng P. Transcranial direct current stimulation (tDCS) enhances reconsolidation of long-term memory. Brain Stimul 2013, 6: 668–674.
Manenti R, Brambilla M, Petesi M, Ferrari C, Cotelli M. Enhancing verbal episodic memory in older and young subjects after non-invasive brain stimulation. Front Aging Neurosci 2013, 5: 49.
Cerruti C, Schlaug G. Anodal transcranial direct current stimulation of the prefrontal cortex enhances complex verbal associative thought. J Cogn Neurosci 2009, 21: 1980–1987.
Metuki N, Sela T, Lavidor M. Enhancing cognitive control components of insight problems solving by anodal tDCS of the left dorsolateral prefrontal cortex. Brain Stimul 2012, 5: 110–115.
Dockery CA, Hueckel-Weng R, Birbaumer N, Plewnia C. Enhancement of planning ability by transcranial direct current stimulation. J Neurosci 2009, 29: 7271–7277.
Santarnecchi E, Polizzotto NR, Godone M, Giovannelli F, Feurra M, Matzen L, et al. Frequency-dependent enhancement of fluid intelligence induced by transcranial oscillatory potentials. Curr Biol 2013, 23: 1449–1453.
Fecteau S, Pascual-Leone A, Zald DH, Liguori P, Théoret H, Boggio PS, et al. Activation of prefrontal cortex by transcranial direct current stimulation reduces appetite for risk during ambiguous decision making. J Neurosci 2007a, 27: 6212–6218.
Fecteau S, Knoch D, Fregni F, Sultani N, Boggio P, Pascual-Leone A. Diminishing risk-taking behavior by modulating activity in the prefrontal cortex: a direct current stimulation study. J Neurosci 2007b, 27: 12500–12505.
Boggio PS, Campanhã C, Valasek CA, Fecteau S, Pascual-Leone A, Fregni F. Modulation of decision-making in a gambling task in older adults with transcranial direct current stimulation. Eur J Neurosci 2010, 31: 593–597.
Pripfl J, Neumann R, Köhler U, Lamm C. Effects of transcranial direct current stimulation on risky decision making are mediated by ‘hot’ and ‘cold’ decisions, personality, and hemisphere. Eur J Neurosci 2013, 38: 3778–3785.
Minati L, Campanhã C, Critchley HD, Boggio PS. Effects of transcranial direct-current stimulation (tDCS) of the dorsolateral prefrontal cortex (DLPFC) during a mixedgambling risky decision-making task. Cogn Neurosci 2012, 3: 80–88.
Knoch D, Nitsche MA, Fischbacher U, Eisenegger C, Pascual-Leone A, Fehr E. Studying the neurobiology of social interaction with transcranial direct current stimulation—the example of punishing unfairness. Cereb Cortex 2008, 18: 1987–1990.
Ruff CC, Ugazio G, Fehr E. Changing social norm compliance with non-invasive brain stimulation. Science 2013, 342: 482–484.
Phan KL, Wager T, Taylor SF, Liberzon I. Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI. Neuroimage 2002, 16: 331–348.
Steele JD, Lawrie SM. Segregation of cognitive and emotional function in the prefrontal cortex: a stereotactic meta-analysis. Neuroimage. 2004, 21: 868–875.
Grimm S, Schmidt CF, Bermpohl F, Heinzel A, Dahlem Y, Wyss M, et al. Segregated neural representation of distinct emotion dimensions in the prefrontal cortex-an fMRI study. Neuroimage 2006, 30: 325–340.
Sergerie K, Lepage M, Armony JL. A face to remember: emotional expression modulates prefrontal activity during memory formation. Neuroimage. 2005, 24: 580–585.
Ueda K, Okamoto Y, Okada G, Yamashita H, Hori T, Yamawaki S. Brain activity during expectancy of emotional stimuli: an fMRI study. Neuroreport 2003, 14: 51–55.
Habel U, Klein M, Kellermann T, Shah NJ, Schneider F. Same or different? Neural correlates of happy and sad mood in healthy males. Neuroimage 2005, 26: 206–214.
Herrington JD, Mohanty A, Koven NS, Fisher JE, Stewart JL, Banich MT, et al. Emotion-modulated performance and activity in left dorsolateral prefrontal cortex. Emotion 2005, 5: 200–207.
Belyi BI. Mental impairment in unilateral frontal tumours: role of the laterality of the lesion. Int J Neurosci 1987, 32: 799–810.
Perini GE. Emotions and personality in complex partial seizures. Psychother Psychosom 1986, 45: 141–148.
Robinson RG, Lipsey JR. Cerebral localization of emotion based on clinical-neuropathological correlations: methodological issues. Psychiatr Dev 1985, 3: 335–347.
Schutter DJ van Honk J. A framework for targeting alternative brain regions with repetitive transcranial magnetic stimulation in the treatment of depression. J Psychiatry Neurosci 2005, 30: 91–97.
Nitsche MA, Koschack J, Pohlers H, Hullemann S, Paulus W, Happe S. Effects of frontal transcranial direct current stimulation on emotional state and processing in healthy humans. Front Psychiatry 2012, 3: 58.
Plazier M, Joos K, Vanneste S, Ost J, De Ridder D. Bifrontal and bioccipital transcranial direct current stimulation (tDCS) does not induce mood changes in healthy volunteers: a placebo controlled study. Brain Stimul 2012, 5: 454–461.
Boggio PS, Zaghi S, Fregni F. Modulation of emotions associated with images of human pain using anodal transcranial direct current stimulation (tDCS). Neuropsychologia. 2009, 47: 212–217.
Maeoka H1, Matsuo A, Hiyamizu M, Morioka S, Ando H. Influence of transcranial direct current stimulation of the dorsolateral prefrontal cortex on pain related emotions: a study using electroencephalographic power spectrum analysis. Neurosci Lett 2012, 512: 12–16.
Peña-Gómez C, Vidal-Piñeiro D, Clemente IC, Pascual-Leone Á, Bartrés-Faz D. Down-regulation of negative emotional processing by transcranial direct current stimulation: effects of personality characteristics. PLoS One 2011, 6: e22812.
Vanderhasselt MA, De Raedt R, Brunoni AR, Campanhã C, Baeken C, Remue J, et al. tDCS over the left prefrontal cortex enhances cognitive control for positive affective stimuli. PLoS One 2013, 8: e62219.
Feeser M, Prehn K, Kazzer P, Mungee A, Bajbouj M. Transcranial direct current stimulation enhances cognitive control during emotion regulation. Brain Stimul 2014, 7: 105–112.
Mungee A, Kazzer P, Feeser M, Nitsche MA, Schiller D, Bajbouj M. Transcranial direct current stimulation of the prefrontal cortex: a means to modulate fear memories. Neuroreport 2014, 25: 480–484.
Edwards D, Cortes M, Datta A, Minhas P, Wassermann EM, Bikson M. Physiological and modeling evidence for focal transcranial electrical brain stimulation in humans: a basis for high-definition tDCS. Neuroimage 2013, 74: 266–275.
Bikson M, Rahman A, Datta A. Computational models of transcranial direct current stimulation. Clin EEG Neurosci 2012, 43176–43183.
Nitsche MA, Doemkes S, Karaköse T, Antal A, Liebetanz D, Lang N, et al. Shaping the effects of transcranial direct current stimulation of the human motor cortex. J Neurophysiol 2007, 97: 3109–3117.
Polanía R, Nitsche MA, Paulus W. Modulating functional connectivity patterns and topological functional organization of the human brain with transcranial direct current stimulation. Hum Brain Mapp 2011, 32: 1236–1249