Experimental validation of a dimensional analysis of spheronisation of cylindrical extrudates

Bryan, 2015, Stages in spheronisation: evolution of pellet size and shape during spheronisation of microcrystalline cellulose-based paste extrudates, Powder Technol., 270, 163, 10.1016/j.powtec.2014.10.014 Haring, 2008, Differences in characteristics of pellets prepared by different pelletization methods, Drug Dev. Ind. Pharm., 34, 289, 10.1080/03639040701655960 Vervaet, 1995, Extrusion–spheronisation: a literature review, Int. J. Pharm., 116, 131, 10.1016/0378-5173(94)00311-R Wilson, 2007, Extrusion–spheronisation, 189 Rowe, 1985, Spheronization: a novel pill-making process?, Pharm. Int., 6, 119 Baert, 1993, Study of parameters important in the spheronisation process, Int. J. Pharm., 96, 225, 10.1016/0378-5173(93)90231-4 Liew, 2007, Elucidation of spheroid formation with and without the extrusion step, AAPS PharmSciTech, 8, 1, 10.1208/pt0801010 Koester, 2012, Systematic evaluations regarding interparticular mass transfer in spheronisation, Int. J. Pharm., 431, 84, 10.1016/j.ijpharm.2012.04.045 Bryan, 2015, The effect of mixing on the extrusion–spheronisation of a micro-crystalline cellulose paste, Int. J. Pharm., 479, 1, 10.1016/j.ijpharm.2014.12.028 Sinka, 2011, A first order numerical study of the spheronisation process, Powder Technol., 206, 195, 10.1016/j.powtec.2010.07.013 Sinka, 2015, A model for the deformation of an ellipsoid subject to a large number of successive impacts with special reference to spheronisation, Powder Technol., 270, 592, 10.1016/j.powtec.2014.07.005 Al-Harbi, 2015, Discrete Element Modelling of Particle Collisions in Granular Flows with Special Reference to Spheronisation Bouffard, 2012, Experimental investigation of the effect of particle cohesion on the flow dynamics in a spheronizer, AIChE J., 59, 1491, 10.1002/aic.13955 Koester, 2013, Analysis of particle kinematics in spheronisation via particle image velocimetry, Eur. J. Pharm. Biopharm., 83, 307, 10.1016/j.ejpb.2012.08.013 Lau, 2014, The evolution of pellet size and shape during spheronisation of an extruded microcrystalline cellulose paste, Chem. Eng. Res. Des., 92, 2413, 10.1016/j.cherd.2014.01.018 Adams, 2004, Modelling collisions of soft agglomerates at the continuum length scale, Powder Technol., 140, 268, 10.1016/j.powtec.2004.01.013 Benbow, 1993 Fielden, 1992, The influence of lactose particle size on spheronisation of extrudate processed by a ram extruder, Int. J. Pharm., 81, 205, 10.1016/0378-5173(92)90013-R Heng, 2001, A study of the effects of the physical characteristics of microcrystalline cellulose on performance in extrusion–spheronisation, Pharm. Res., 18, 480, 10.1023/A:1011054310895 Macritchie, 2002, The evaluation of the rheological properties of lactose/microcrystalline cellulose and water mixtures by controlled stress rheometry and the relationship to the production of spherical pellets by extrusion–spheronisation, Eur J. Pharm. Sci., 17, 43, 10.1016/S0928-0987(02)00130-6 Zhang, 2011, A comparison of ram extrusion by single-holed and multi-holed dies for extrusion–spheronisation of microcrystalline-based pastes, Int. J. Pharm., 416, 210, 10.1016/j.ijpharm.2011.05.037 Wilson, 2012, Paste engineering: multi-phase materials and multi-phase flows, Can. J. Chem. Eng., 90, 277, 10.1002/cjce.20656 Kumar, 1999, Fall cone and compression tests on clay-gravel mixtures, Géotechnique, 49, 727, 10.1680/geot.1999.49.6.727 Chopra, 2002, The influence of pellet shape and film coating on the filling of pellets into hard sphere capsules, Eur. J. Pharm. Biopharm., 53, 327, 10.1016/S0939-6411(02)00015-2 Chapman, 1988, Characterisation of the sphericity of particles by the one plane critical stability, J. Pharm. Pharmacol., 40, 503, 10.1111/j.2042-7158.1988.tb05286.x Krueger, 2012, Spheronisation mechanism of MCC II-based pellets, Powder Technol., 238, 176, 10.1016/j.powtec.2011.12.052