Expanded FMR1 alleles are rare in idiopathic Parkinson’s disease

Neurogenetics - Tập 6 - Trang 51-52 - 2004
E. K. Tan1,2,3, Y. Zhao4, K. Y. Puong4, H. Y. Law5, L. L. Chan6, K. Yew1, H. Shen1, V. R. Chandran4, Y. Yuen7, R. Pavanni1,2, M. C. Wong1,2, I. S. Ng5
1Department of Neurology, Singapore General Hospital, Singapore
2National Neuroscience Institute, Singapore
3SingHealth Research, Singapore
4Department of Clinical Research, Singapore General Hospital, Singapore
5KK Women's and Children's Hospital, Singapore
6Department of Diagnostic Radiology, Singapore General Hospital, Singapore
7Department of Health Screening, Singapore General Hospital, Singapore

Tài liệu tham khảo

Hagerman RJ, Leehey M, Heinrichs W, et al (2001) Intention tremor, parkinsonism, and generalized brain atrophy in male carriers of fragile X. Neurology 57:127–130 Jacquemont S, Hagerman RJ, Leehey M, et al (2003) Fragile X premutation tremor/ataxia syndrome: molecular, clinical, and neuroimaging correlates. Am J Hum Genet 72:869–878 Tassone F, Hagerman RJ, Taylor AK, et al (2000) Elevated levels of FMR1 mRNA in carrier males: a new mechanism of involvement in fragile X syndrome. Am J Hum Genet 66:6–15 Leehey, Zhang L, Wheelock V, Tassone F, Hagerman R, Hagerman PJ (2004) A preliminary observation: increased frequency of fragile X expanded alleles in patients that meet the diagnostic criteria for MSA. Mov Disord 19: [Suppl 9]:S339 Tan EK, Zhao Y, Puong KY, et al (2004) Fragile X premutation alleles in SCA, ET, and parkinsonism in an Asian cohort. Neurology 63:362–363 Leehey E, Berry-Kravis E, Jacquemont, Zhang L, Hagerman R, Hagerman PJ (2004) Misdiagnosis of fragile X associated tremor/ataxia syndrome (FXTAS). Mov Disord 19 [Suppl 9]:S338