Exercise, spinogenesis and cognitive functions
Tài liệu tham khảo
Adkins, 2006, Motor training induces experience-specific patterns of plasticity across motor cortex and spinal cord, Journal of Applied Physiology, 101, 1776, 10.1152/japplphysiol.00515.2006
Ahlskog, 2018, Aerobic exercise: Evidence for a direct brain effect to slow parkinson disease progression, Mayo Clinic Proceedings, 93, 360, 10.1016/j.mayocp.2017.12.015
Ambrogini, 2013, Physical exercise and environment exploration affect synaptogenesis in adult-generated neurons in the rat dentate gyrus: Possible role of BDNF, Brain Research, 1534, 1, 10.1016/j.brainres.2013.08.023
Anderson, 1996, Motor-skill learning: Changes in synaptic organization of the rat cerebellar cortex, Neurobiology of Learning and Memory, 66, 221, 10.1006/nlme.1996.0062
Anderson, 1994, Glial hypertrophy is associated with synaptogenesis following motor-skill learning, but not with angiogenesis following exercise, Glia, 11, 73, 10.1002/glia.440110110
Aoki, 2018, Journal of Neuroscience Research, 96, 1450, 10.1002/jnr.24035
Basso, 2015, Acute exercise improves prefrontal cortex but not hippocampal function in healthy adults, Journal of the International Neuropsychological Society, 21, 791, 10.1017/S135561771500106X
Bennett, 2011, The prefrontal-limbic network in depression: A core pathology of synapse regression, Progress in Neurobiology, 93, 457, 10.1016/j.pneurobio.2011.01.001
Bookout, 2013, FGF21 regulates metabolism and circadian behavior by acting on the nervous system, Nature Medicine, 19, 1147, 10.1038/nm.3249
Brockett, 2015, Physical exercise enhances cognitive flexibility as well as astrocytic and synaptic markers in the medial prefrontal cortex, PLoS One, 10, 10.1371/journal.pone.0124859
Bruel-Jungerman, 2009, Inhibition of PI3K-Akt signaling blocks exercise-mediated enhancement of adult neurogenesis and synaptic plasticity in the dentate gyrus, PLoS One, 4, 10.1371/journal.pone.0007901
Campos, 2017, Exercise induced neuroplasticity to enhance therapeutic outcomes of cognitive remediation in Schizophrenia: Analyzing the role of brai nderived neurotrophic factor, CNS & Neurological Disorders Drug Targets, 16, 638, 10.2174/1871527315666161223142918
Carta, 2019, Cerebellar modulation of the reward circuitry and social behavior, Science, 363, eaav0581, 10.1126/science.aav0581
Cass, 2017, Alzheimer's disease and exercise: A literature review, Current Sports Medicine Reports, 16, 19, 10.1249/JSR.0000000000000332
Chekroud, 2018, Association between physical exercise and mental health in 1.2 million individuals in the USA between 2011 and 2015: A cross-sectional study, Lancet Psychiatry, 5, 739, 10.1016/S2215-0366(18)30227-X
Chen, 2017, NR2A- and NR2B-NMDA receptors and drebrin within postsynaptic spines of the hippocampus correlate with hunger-evoked exercise, Brain Structure & Function, 222, 2271, 10.1007/s00429-016-1341-7
Chen, 2018, Selective activation of parvalbumin interneurons prevents stress-induced synapse loss and perceptual defects, Molecular Psychiatry, 23, 1614, 10.1038/mp.2017.159
Chen, 2016, The role of medial prefrontal corticosterone and dopamine in the antidepressant-like effect of exercise, Psychoneuroendocrinology, 69, 1, 10.1016/j.psyneuen.2016.03.008
Chen, 2017, Treadmill exercise improves motor dysfunction and hyperactivity of the corticostriatal glutamatergic pathway in rats with 6-OHDA-induced Parkinson's disease, Neural Plasticity, 2017, 2583910, 10.1155/2017/2583910
Chen, 2017, Treadmill exercise suppressed stress-induced dendritic spine elimination in mouse barrel cortex and improved working memory via BDNF/TrkB pathway, Translational Psychiatry, 7, 10.1038/tp.2017.41
Chen, 2019, Exercise training improves motor skill learning via selective activation of mTOR, Science Advances, 5, 10.1126/sciadv.aaw1888
Choi, 2018, Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model, Science, 361, 10.1126/science.aan8821
Churchill, 2017, Exercise in an animal model of Parkinson's disease: Motor recovery but not restoration of the nigrostriatal pathway, Neuroscience, 359, 224, 10.1016/j.neuroscience.2017.07.031
Collin, 2004, Motor training compensates for cerebellar dysfunctions caused by oligodendrocyte ablation, Proceedings of the National Academy of Sciences of the United States of America, 101, 325, 10.1073/pnas.0305994101
Crowley, 2019, Exercise as a therapeutic intervention for motor and non-motor symptoms in Parkinson's disease: Evidence from rodent models, Progress in Neurobiology, 172, 2, 10.1016/j.pneurobio.2018.11.003
Cui, 2018, Exercise intervention associated with cognitive improvement in Alzheimer's disease, Neural Plasticity, 2018, 9234105, 10.1155/2018/9234105
Dao, 2015, Moderate treadmill exercise protects synaptic plasticity of the dentate gyrus and related signaling cascade in a rat model of Alzheimer's disease, Molecular Neurobiology, 52, 1067, 10.1007/s12035-014-8916-1
Dao, 2016, Comparison of the effect of exercise on late-phase LTP of the Dentate Gyrus and CA1 of Alzheimer's disease model, Molecular Neurobiology, 53, 6859, 10.1007/s12035-015-9612-5
Dao, 2013, Treadmill exercise prevents learning and memory impairment in Alzheimer's disease-like pathology, Current Alzheimer Research, 10, 507, 10.2174/1567205011310050006
D'Arcangelo, 2000, Interleukin-6 inhibits neurotransmitter release and the spread of excitation in the rat cerebral cortex, The European Journal of Neuroscience, 12, 1241, 10.1046/j.1460-9568.2000.00011.x
Dhar, 2014, Leptin induces hippocampal synaptogenesis via CREB-regulated microRNA-132 suppression of p250GAP, Molecular Endocrinology, 28, 1073, 10.1210/me.2013-1332
Dietrich, 2008, Exercise-induced synaptogenesis in the hippocampus is dependent on UCP2-regulated mitochondrial adaptation, The Journal of Neuroscience, 28, 10766, 10.1523/JNEUROSCI.2744-08.2008
Dietrich, 2005, Exercise affects glutamate receptors in postsynaptic densities from cortical mice brain, Brain Research, 1065, 20, 10.1016/j.brainres.2005.09.038
Dong, 2018, Exercise improves recognition memory and synaptic plasticity in the prefrontal cortex for rats modelling vascular dementia, Neurological Research, 40, 68, 10.1080/01616412.2017.1398389
Eadie, 2005, Voluntary exercise alters the cytoarchitecture of the adult dentate gyrus by increasing cellular proliferation, dendritic complexity, and spine density, Journal of Comparative Neurology, 486, 39, 10.1002/cne.20493
Eddy, 2017, Running wheel exercise reduces renewal of extinguished instrumental behavior and alters medial prefrontal cortex neurons in adolescent, but not adult, rats, Behavioral Neuroscience, 131, 460, 10.1037/bne0000218
Eisch, 2012, Depression and hippocampal neurogenesis: A road to remission?, Science, 338, 72, 10.1126/science.1222941
Elfving, 2013, Transient activation of mTOR following forced treadmill exercise in rats, Synapse, 67, 620, 10.1002/syn.21668
Erickson, 2011, Exercise training increases size of hippocampus and improves memory, Proceedings of the National Academy of Sciences of the United States of America, 108, 3017, 10.1073/pnas.1015950108
Erickson, 2012, Physical activity, brain plasticity, and Alzheimer's disease, Archives of Medical Research, 43, 615, 10.1016/j.arcmed.2012.09.008
Evans, 2017, Metabolism of ketone bodies during exercise and training: Physiological basis for exogenous supplementation, The Journal of Physiology, 595, 2857, 10.1113/JP273185
Falkai, 2017, Aerobic exercise and its effects on cognition in schizophrenia, Current Opinion in Psychiatry, 30, 171, 10.1097/YCO.0000000000000326
Fang, 2013, Effect of treadmill exercise on the BDNF-mediated pathway in the hippocampus of stressed rats, Neuroscience Research, 76, 187, 10.1016/j.neures.2013.04.005
Fattoretti, 2018, Modulatory effect of aerobic physical activity on synaptic ultrastructure in the old mouse hippocampus, Frontiers in Aging Neuroscience, 10, 141, 10.3389/fnagi.2018.00141
Firth, 2017, Aerobic exercise improves cognitive functioning in people with Schizophrenia: A systematic review and meta-analysis, Schizophrenia Bulletin, 43, 546
Foster, 2011, Exercise-induced cognitive plasticity, implications for mild cognitive impairment and Alzheimer's disease, Frontiers in Neurology, 2, 28, 10.3389/fneur.2011.00028
Fuss, 2013, Hippocampal serotonin-1A receptor function in a mouse model of anxiety induced by long-term voluntary wheel running, Synapse, 67, 648, 10.1002/syn.21666
Garcia, 2017, The impact of short and long-term exercise on the expression of arc and ampars during evolution of the 6-Hydroxy-Dopamine animal model of Parkinson's disease, Journal of Molecular Neuroscience, 61, 542, 10.1007/s12031-017-0896-y
Garcia, 2012, Different protocols of physical exercise produce different effects on synaptic and structural proteins in motor areas of the rat brain, Brain Research, 1456, 36, 10.1016/j.brainres.2012.03.059
Garcia-Mesa, 2011, Physical exercise protects against Alzheimer's disease in 3xTg-AD mice, Journal of Alzheimer's Disease, 24, 421, 10.3233/JAD-2011-101635
Garcia-Mesa, 2014, Physical exercise neuroprotects ovariectomized 3xTg-AD mice through BDNF mechanisms, Psychoneuroendocrinology, 45, 154, 10.1016/j.psyneuen.2014.03.021
Geerlings, 2017, Late-life depression, hippocampal volumes, and hypothalamic-pituitary-adrenal axis regulation: A systematic review and meta-analysis, Biological Psychiatry, 82, 339, 10.1016/j.biopsych.2016.12.032
Giles, 2017, Habitual exercise is associated with cognitive control and cognitive reappraisal success, Experimental Brain Research, 235, 3785, 10.1007/s00221-017-5098-x
Giudice, 2017, Muscle as a paracrine and endocrine organ, Current Opinion in Pharmacology, 34, 49, 10.1016/j.coph.2017.05.005
Gomes da Silva, 2012, Early exercise promotes positive hippocampal plasticity and improves spatial memory in the adult life of rats, Hippocampus, 22, 347, 10.1002/hipo.20903
Gomez-Rubio, 2019, The effects of exercise on IL-6 levels and cognitive performance in patients with Schizophrenia, Diseases, 7, 10.3390/diseases7010011
Gordon, 2018, Association of efficacy of resistance exercise training with depressive symptoms: Meta-analysis and meta-regression analysis of randomized clinical trials, JAMA Psychiatry, 75, 566, 10.1001/jamapsychiatry.2018.0572
Greenwood, 2013, Exercise-induced stress resistance is independent of exercise controllability and the medial prefrontal cortex, The European Journal of Neuroscience, 37, 469, 10.1111/ejn.12044
Gumusoglu, 2017, The role of IL-6 in neurodevelopment after prenatal stress, Brain, Behavior, and Immunity, 65, 274, 10.1016/j.bbi.2017.05.015
Guo, 2015, Dynamic rewiring of neural circuits in the motor cortex in mouse models of Parkinson's disease, Nature Neuroscience, 18, 1299, 10.1038/nn.4082
Hamilton, 2015, Voluntary exercise partially reverses neonatal alcohol-induced deficits in mPFC layer II/III dendritic morphology of male adolescent rats, Synapse, 69, 405, 10.1002/syn.21827
Harward, 2016, Autocrine BDNF-TrkB signalling within a single dendritic spine, Nature, 538, 99, 10.1038/nature19766
He, 2017, Voluntary exercise promotes glymphatic clearance of amyloid beta and reduces the activation of astrocytes and microglia in aged mice, Frontiers in Molecular Neuroscience, 10, 144, 10.3389/fnmol.2017.00144
Herring, 2012, Exercise during pregnancy mitigates Alzheimer-like pathology in mouse offspring, The FASEB Journal, 26, 117, 10.1096/fj.11-193193
Herring, 2016, Late running is not too late against Alzheimer's pathology, Neurobiology of Disease, 94, 44, 10.1016/j.nbd.2016.06.003
Hescham, 2009, Effect of exercise on synaptophysin and calcium/calmodulin-dependent protein kinase levels in prefrontal cortex and hippocampus of a rat model of developmental stress, Metabolic Brain Disease, 24, 701, 10.1007/s11011-009-9165-2
Hill, 2019, FGF21 signals protein status to the brain and adaptively regulates food choice and metabolism, Cell Reports, 27, 2934, 10.1016/j.celrep.2019.05.022
Hoffman, 2016, Exercise maintains dendritic complexity in an animal model of posttraumatic stress disorder, Medicine and Science in Sports and Exercise, 48, 2487, 10.1249/MSS.0000000000001038
Hou, 2017, Exercise-induced neuroprotection of the nigrostriatal dopamine system in Parkinson's disease, Frontiers in Aging Neuroscience, 9, 358, 10.3389/fnagi.2017.00358
Hsueh, 2018, Voluntary physical exercise improves subsequent motor and cognitive impairments in a rat model of Parkinson's disease, International Journal of Molecular Sciences, 19, 10.3390/ijms19020508
Huang, 2012, Neurogenomic evidence for a shared mechanism of the antidepressant effects of exercise and chronic fluoxetine in mice, PLoS One, 7, 10.1371/journal.pone.0035901
Iggena, 2019, Physical activity sustains memory retrieval in dopamine-depleted mice previously treated with L-Dopa, Behavioural Brain Research, 369, 111915, 10.1016/j.bbr.2019.111915
Imai, 2016, Synapse formation in monosynaptic sensory-motor connections is regulated by presynaptic rho GTPase Cdc42, The Journal of Neuroscience, 36, 5724, 10.1523/JNEUROSCI.2146-15.2016
Inoue, 2018, Effects of long-term exercise and low-level inhibition of GABAergic synapses on motor control and the expression of BDNF in the motor related cortex, Neurological Research, 40, 18, 10.1080/01616412.2017.1382801
Isaacs, 1992, Exercise and the brain: angiogenesis in the adult rat cerebellum after vigorous physical activity and motor skill learning, Journal of Cerebral Blood Flow and Metabolism, 12, 110, 10.1038/jcbfm.1992.14
Jang, 2018, Endurance exercise mediates neuroprotection against MPTP-mediated Parkinson's disease via enhanced neurogenesis, antioxidant capacity, and autophagy, Neuroscience, 379, 292, 10.1016/j.neuroscience.2018.03.015
Jiang, 2015, CaMKII-dependent dendrite ramification and spine generation promote spatial training-induced memory improvement in a rat model of sporadic Alzheimer's disease, Neurobiology of Aging, 36, 867, 10.1016/j.neurobiolaging.2014.10.018
Jones, 1999, Motor skills training enhances lesion-induced structural plasticity in the motor cortex of adult rats, The Journal of Neuroscience, 19, 10153, 10.1523/JNEUROSCI.19-22-10153.1999
Kao, 2009, Exercise induces cortical plasticity after neonatal spinal cord injury in the rat, The Journal of Neuroscience, 29, 7549, 10.1523/JNEUROSCI.2474-08.2009
Kassa, 2017, Effect of physical exercise and anabolic steroid treatment on spinal motoneurons and surrounding glia of wild-type and ALS mice, Brain Research, 1657, 269, 10.1016/j.brainres.2016.12.029
Kim, 2013, Treadmill exercise ameliorates motor disturbance through inhibition of apoptosis in the cerebellum of valproic acid-induced autistic rat pups, Molecular Medicine Reports, 8, 327, 10.3892/mmr.2013.1518
Kim, 2014, Increase of circulating BDNF levels and its relation to improvement of physical fitness following 12 weeks of combined exercise in chronic patients with schizophrenia: A pilot study, Psychiatry Research, 220, 792, 10.1016/j.psychres.2014.09.020
Kintz, 2017, Treadmill exercise modifies dopamine receptor expression in the prefrontal cortex of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of Parkinson's disease, Neuroreport, 28, 987, 10.1097/WNR.0000000000000865
Kleim, 2007, Motor learning induces astrocytic hypertrophy in the cerebellar cortex, Behavioural Brain Research, 178, 244, 10.1016/j.bbr.2006.12.022
Kramer, 2007, Capitalizing on cortical plasticity: Influence of physical activity on cognition and brain function, Trends in Cognitive Sciences, 11, 342, 10.1016/j.tics.2007.06.009
Kuroda, 2017, Peripherally derived FGF21 promotes remyelination in the central nervous system, The Journal of Clinical Investigation, 127, 3496, 10.1172/JCI94337
Lange-Asschenfeldt, 2008, Alzheimer's disease, cerebrovascular dysfunction and the benefits of exercise: From vessels to neurons, Experimental Gerontology, 43, 499, 10.1016/j.exger.2008.04.002
Lee, 2009, Activation of CaMKII in single dendritic spines during long-term potentiation, Nature, 458, 299, 10.1038/nature07842
Li, 2017, Aerobic exercise regulates Rho/cofilin pathways to rescue synaptic loss in aged rats, PLoS One, 12
Lin, 2012, Different types of exercise induce differential effects on neuronal adaptations and memory performance, Neurobiology of Learning and Memory, 97, 140, 10.1016/j.nlm.2011.10.006
Lin, 2015, Running exercise delays neurodegeneration in amygdala and hippocampus of Alzheimer's disease (APP/PS1) transgenic mice, Neurobiology of Learning and Memory, 118, 189, 10.1016/j.nlm.2014.12.005
Lin, 2018, Physical exercise enhances neuroplasticity and delays Alzheimer's disease, Brain Plasticity, 4, 95, 10.3233/BPL-180073
Liston, 2011, Glucocorticoids are critical regulators of dendritic spine development and plasticity in vivo, Proceedings of the National Academy of Sciences of the United States of America, 108, 16074, 10.1073/pnas.1110444108
Llorens-Martin, 2016, Retroviral induction of GSK-3beta expression blocks the stimulatory action of physical exercise on the maturation of newborn neurons, Cellular and Molecular Life Sciences, 73, 3569, 10.1007/s00018-016-2181-6
Lourenco, 2019, Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models, Nature Medicine, 25, 165, 10.1038/s41591-018-0275-4
Lowe, 2017, Effects of moderate exercise on cortical resilience: A transcranial magnetic stimulation study targeting the dorsolateral prefrontal cortex, Psychosomatic Medicine, 79, 143, 10.1097/PSY.0000000000000361
Lu, 2017, Treadmill exercise exerts neuroprotection and regulates microglial polarization and oxidative stress in a Streptozotocin-induced rat model of sporadic Alzheimer's disease, Journal of Alzheimer's Disease, 56, 1469, 10.3233/JAD-160869
Lu, 2014, Exercise ameliorates depression-like behavior and increases hippocampal BDNF level in ovariectomized rats, Neuroscience Letters, 573, 13, 10.1016/j.neulet.2014.04.053
Lunetta, 2016, Strictly monitored exercise programs reduce motor deterioration in ALS:Preliminary results of a randomized controlled trial, Journal of Neurology, 263, 52, 10.1007/s00415-015-7924-z
Ma, 2017, Physical exercise induces hippocampal neurogenesis and prevents cognitive decline, Behavioural Brain Research, 317, 332, 10.1016/j.bbr.2016.09.067
Mang, 2016, High-intensity aerobic exercise enhances motor memory retrieval, Medicine and Science in Sports and Exercise, 48, 2477, 10.1249/MSS.0000000000001040
Matsui, 2017, Astrocytic glycogen-derived lactate fuels the brain during exhaustive exercise to maintain endurance capacity, Proceedings of the National Academy of Sciences of the United States of America, 114, 6358, 10.1073/pnas.1702739114
Milaneschi, 2017, Leptin dysregulation is specifically associated with major depression with atypical features: Evidence for a mechanism connecting obesity and depression, Biological Psychiatry, 81, 807, 10.1016/j.biopsych.2015.10.023
Minichino, 2014, The role of cerebellum in unipolar and bipolar depression: A review of the main neurobiological findings, Rivista di Psichiatria, 49, 124
Molteni, 2002, Differential effects of acute and chronic exercise on plasticity-related genes in the rat hippocampus revealed by microarray, The European Journal of Neuroscience, 16, 1107, 10.1046/j.1460-9568.2002.02158.x
Moon, 2016, Running-induced systemic Cathepsin B secretion is associated with memory function, Cell Metabolism, 24, 332, 10.1016/j.cmet.2016.05.025
Moriya, 2016, Effects of physical exercise on working memory and prefrontal cortex function in post-stroke patients, Advances in Experimental Medicine and Biology, 923, 203, 10.1007/978-3-319-38810-6_27
Morland, 2017, Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1, Nature Communications, 8, 15557, 10.1038/ncomms15557
Nelson, 2012, Altered synaptic transmission in the hippocampus of transgenic mice with enhanced central nervous systems expression of interleukin-6, Brain, Behavior, and Immunity, 26, 959, 10.1016/j.bbi.2012.05.005
Nigam, 2017, Exercise and BDNF reduce Abeta production by enhancing alpha-secretase processing of APP, Journal of Neurochemistry, 142, 286, 10.1111/jnc.14034
Nishiguchi, 2015, A 12-week physical and cognitive exercise program can improve cognitive function and neural efficiency in community-dwelling older adults: A randomized controlled trial, Journal of the American Geriatrics Society, 63, 1355, 10.1111/jgs.13481
Northey, 2018, Exercise interventions for cognitive function in adults older than 50: A systematic review with meta-analysis, British Journal of Sports Medicine, 52, 154, 10.1136/bjsports-2016-096587
Nybo, 2002, Interleukin-6 release from the human brain during prolonged exercise, The Journal of Physiology, 542, 991, 10.1113/jphysiol.2002.022285
O'Dell, 2012, Running wheel exercise ameliorates methamphetamine-induced damage to dopamine and serotonin terminals, Synapse, 66, 71, 10.1002/syn.20989
Oliveira, 2018, Effects of acute aerobic exercise on rats serum extracellular vesicles diameter, concentration and small rnas content, Frontiers in Physiology, 9, 532, 10.3389/fphys.2018.00532
Pajonk, 2010, Hippocampal plasticity in response to exercise in Schizophrenia, Archives of General Psychiatry, 67, 133, 10.1001/archgenpsychiatry.2009.193
Pedersen, 2011, Exercise-induced liver chemokine CXCL-1 expression is linked to muscle-derived interleukin-6 expression, The Journal of Physiology, 589, 1409, 10.1113/jphysiol.2010.200733
Petzinger, 2013, Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease, Lancet Neurology, 12, 716, 10.1016/S1474-4422(13)70123-6
Pysh, 1979, Exercise during development induces an increase in Purkinje cell dendritic tree size, Science, 206, 230, 10.1126/science.482938
Rafie, 2017, Effect of exercise intervention on the perceptual-motor skills in adolescents with autism, The Journal of Sports Medicine and Physical Fitness, 57, 53, 10.23736/S0022-4707.16.05919-3
Rajasethupathy, 2015, Projections from neocortex mediate top-down control of memory retrieval, Nature, 526, 653, 10.1038/nature15389
Real, 2019, Evaluation of exercise-induced modulation of glial activation and dopaminergic damage in a rat model of Parkinson's disease using [(11)C]PBR28 and [(18)F]FDOPA PET, Journal of Cerebral Blood Flow and Metabolism, 39, 989, 10.1177/0271678X17750351
Real, 2017, Treadmill exercise prevents increase of neuroinflammation markers involved in the dopaminergic damage of the 6-OHDA Parkinson's disease model, Journal of Molecular Neuroscience, 63, 36, 10.1007/s12031-017-0955-4
Ren, 2017, Effects of different training loads on emotional state and mrna and protein expressions of N-methyl-D-aspartate receptor subunits, postsynaptic density 95, and kinesin family member 17 in hippocampus of rats, Medical Science Monitor, 23, 4954, 10.12659/MSM.906781
Revilla, 2014, Physical exercise improves synaptic dysfunction and recovers the loss of survival factors in 3xTg-AD mouse brain, Neuropharmacology, 81, 55, 10.1016/j.neuropharm.2014.01.037
Rodriguez, 2011, Voluntary running and environmental enrichment restores impaired hippocampal neurogenesis in a triple transgenic mouse model of Alzheimer's disease, Current Alzheimer Research, 8, 707, 10.2174/156720511797633214
Rudolph, 2018, Maternal IL-6 during pregnancy can be estimated from newborn brain connectivity and predicts future working memory in offspring, Nature Neuroscience, 21, 765, 10.1038/s41593-018-0128-y
Sacheli, 2018, Habitual exercisers versus sedentary subjects with Parkinson's Disease: Multimodal PET and fMRI study, Movement Disorders, 33, 1945, 10.1002/mds.27498
Safdar, 2016, The potential of endurance exercise-derived exosomes to treat metabolic diseases, Nature Reviews. Endocrinology, 12, 504, 10.1038/nrendo.2016.76
Safdar, 2018, Exosomes as mediators of the systemic adaptations to endurance exercise, Cold Spring Harbor Perspectives in Medicine, 8, 10.1101/cshperspect.a029827
Saraulli, 2017, The long run: Neuroprotective effects of physical exercise on adult neurogenesis from youth to old age, Current Neuropharmacology, 15, 519, 10.2174/1570159X14666160412150223
Sarris, 2014, Lifestyle medicine for depression, BMC Psychiatry, 14, 107, 10.1186/1471-244X-14-107
Schmitz Olin, 2017, The effects of exercise dose on stereotypical behavior in children with autism, Medicine and Science in Sports and Exercise, 49, 983, 10.1249/MSS.0000000000001197
Seo, 2013, Treadmill exercise improves behavioral outcomes and spatial learning memory through up-regulation of reelin signaling pathway in autistic rats, Journal of Exercise Rehabilitation, 9, 220, 10.12965/jer.130003
Shih, 2019, Physical activity mediates the association between striatal dopamine transporter availability and cognition in Parkinson's disease, Parkinsonism & Related Disorders, 10.1016/j.parkreldis.2019.01.027
Shimazu, 2013, Suppression of oxidative stress by beta-hydroxybutyrate, an endogenous histone deacetylase inhibitor, Science, 339, 211, 10.1126/science.1227166
Shin, 2016, Treadmill exercise facilitates synaptic plasticity on dopaminergic neurons and fibers in the mouse model with Parkinson's disease, Neuroscience Letters, 621, 28, 10.1016/j.neulet.2016.04.015
Shinko, 1977, Effect of motor training on evoked potentials and synaptic organization of sensomotor cortical neurons in rats during ontogeny, Neuroscience and Behavioral Physiology, 8, 91, 10.1007/BF01186936
Siette, 2013, Age-specific effects of voluntary exercise on memory and the older brain, Biological Psychiatry, 73, 435, 10.1016/j.biopsych.2012.05.034
Sleiman, 2016, Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body beta-hydroxybutyrate, eLife, 5, e15092, 10.7554/eLife.15092
Song, 2015, Brain-derived neurotrophic factor in Alzheimer's disease: Risk, mechanisms, and therapy, Molecular Neurobiology, 52, 1477, 10.1007/s12035-014-8958-4
Soto, 2015, APOE stabilization by exercise prevents aging neurovascular dysfunction and complement induction, PLoS Biology, 13, 10.1371/journal.pbio.1002279
Stranahan, 2009, Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice, Hippocampus, 19, 951, 10.1002/hipo.20577
Svatkova, 2015, Physical exercise keeps the brain connected: Biking increases white matter integrity in patients with schizophrenia and healthy controls, Schizophrenia Bulletin, 41, 869, 10.1093/schbul/sbv033
Swiatkiewicz, 2017, Increases in brain (1)H-MR glutamine and glutamate signals following acute exhaustive endurance exercise in the rat, Frontiers in Physiology, 8, 19, 10.3389/fphys.2017.00019
Takashima, 2006, GSK-3 is essential in the pathogenesis of Alzheimer's disease, Journal of Alzheimer's Disease, 9, 309, 10.3233/JAD-2006-9S335
Tamakoshi, 2014, Motor skills training promotes motor functional recovery and induces synaptogenesis in the motor cortex and striatum after intracerebral hemorrhage in rats, Behavioural Brain Research, 260, 34, 10.1016/j.bbr.2013.11.034
Tan, 2016, A meta-analytic review of the efficacy of physical exercise interventions on cognition in individuals with autism spectrum disorder and ADHD, Journal of Autism and Developmental Disorders, 46, 3126, 10.1007/s10803-016-2854-x
Tang, 2014, Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits, Neuron, 83, 1131, 10.1016/j.neuron.2014.07.040
Thompson, 2017, Impaired communication between the motor and somatosensory homunculus is associated with poor manual dexterity in autism spectrum disorder, Biological Psychiatry, 81, 211, 10.1016/j.biopsych.2016.06.020
Toscano-Silva, 2010, Hippocampal mossy fiber sprouting induced by forced and voluntary physical exercise, Physiology & Behavior, 101, 302, 10.1016/j.physbeh.2010.05.012
Tsai, 2018, Long-term moderate exercise rescues age-related decline in hippocampal neuronal complexity and memory, Gerontology, 64, 551, 10.1159/000488589
Tsai, 2018, An acute bout of aerobic or strength exercise specifically modifies circulating exerkine levels and neurocognitive functions in elderly individuals with mild cognitive impairment, NeuroImage. Clinical, 17, 272, 10.1016/j.nicl.2017.10.028
Tse, 2018, Choosing an appropriate physical exercise to reduce stereotypic behavior in children with autism spectrum disorders: A non-randomized crossover study, Journal of Autism and Developmental Disorders, 48, 1666, 10.1007/s10803-017-3419-3
Tsiloulis, 2015, Exercise and the regulation of adipose tissue metabolism, Progress in Molecular Biology and Translational Science, 135, 175, 10.1016/bs.pmbts.2015.06.016
Uysal, 2017, Exercise increases leptin levels correlated with IGF-1 in hippocampus and prefrontal cortex of adolescent male and female rats, Journal of Chemical Neuroanatomy, 81, 27, 10.1016/j.jchemneu.2017.02.004
van Dongen, 2016, Physical exercise performed four hours after learning improves memory retention and increases hippocampal pattern similarity during retrieval, Current Biology, 26, 1722, 10.1016/j.cub.2016.04.071
van Praag, 1999, Running enhances neurogenesis, learning, and long-term potentiation in mice, Proceedings of the National Academy of Sciences of the United States of America, 96, 13427, 10.1073/pnas.96.23.13427
van Praag, 1999, Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus, Nature Neuroscience, 2, 266, 10.1038/6368
VanLeeuwen, 2010, Altered AMPA receptor expression with treadmill exercise in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury, Journal of Neuroscience Research, 88, 650
Vanvuchelen, 2007, Nature of motor imitation problems in school-aged boys with autism: A motor or a cognitive problem?, Autism, 11, 225, 10.1177/1362361307076846
Vaynman, 2006, Exercise differentially regulates synaptic proteins associated to the function of BDNF, Brain Research, 1070, 124, 10.1016/j.brainres.2005.11.062
Vereyken, 2007, Chronic interleukin-6 alters the level of synaptic proteins in hippocampus in culture and in vivo, The European Journal of Neuroscience, 25, 3605, 10.1111/j.1460-9568.2007.05615.x
Veronezi, 2016, Evidence for increased motor cortical facilitation and decreased inhibition in atypical depression, Acta Psychiatrica Scandinavica, 134, 172, 10.1111/acps.12565
Vigo, 2016, Estimating the true global burden of mental illness, Lancet Psychiatry, 3, 171, 10.1016/S2215-0366(15)00505-2
Vinel, 2018, The exerkine apelin reverses age-associated sarcopenia, Nature Medicine, 24, 1360, 10.1038/s41591-018-0131-6
Voss, 2013, Bridging animal and human models of exercise-induced brain plasticity, Trends in Cognitive Sciences, 17, 525, 10.1016/j.tics.2013.08.001
Wagner, 2017, Changes in fMRI activation in anterior hippocampus and motor cortex during memory retrieval after an intense exercise intervention, Biological Psychology, 124, 65, 10.1016/j.biopsycho.2017.01.003
Wang, 2014, The cerebellum, sensitive periods, and autism, Neuron, 83, 518, 10.1016/j.neuron.2014.07.016
Wang, 2018, Aberrant development and synaptic transmission of cerebellar cortex in a VPA induced mouse autism model, Frontiers in Cellular Neuroscience, 12, 500, 10.3389/fncel.2018.00500
Wei, 2018, Long-term moderate exercise enhances specific proteins that constitute neurotrophin signaling pathway: A TMT-based quantitative proteomic analysis of rat plasma, Journal of Proteomics, 185, 39, 10.1016/j.jprot.2018.06.017
Woodward, 2018, Hippocampal volume and vasculature before and after exercise in treatment-resistant schizophrenia, Schizophrenia Research, 202, 158, 10.1016/j.schres.2018.06.054
Wrann, 2013, Exercise induces hippocampal BDNF through a PGC-1alpha/FNDC5 pathway, Cell Metabolism, 18, 649, 10.1016/j.cmet.2013.09.008
Wu, 2018, Effects of sevoflurane exposure during mid-pregnancy on learning and memory in offspring rats: Beneficial effects of maternal exercise, Frontiers in Cellular Neuroscience, 12, 122, 10.3389/fncel.2018.00122
Xu, 2017, Running-induced memory enhancement correlates with the preservation of thin spines in the hippocampal area CA1 of old C57BL/6 mice, Neurobiology of Aging, 52, 106, 10.1016/j.neurobiolaging.2017.01.002
Yanagisawa, 2010, Acute moderate exercise elicits increased dorsolateral prefrontal activation and improves cognitive performance with Stroop test, NeuroImage, 50, 1702, 10.1016/j.neuroimage.2009.12.023
Yang, 2015, The effects of aerobic exercise on cognitive function of Alzheimer's disease patients, CNS & Neurological Disorders Drug Targets, 14, 1292, 10.2174/1871527315666151111123319
Yau, 2011, Hippocampal neurogenesis and dendritic plasticity support running-improved spatial learning and depression-like behaviour in stressed rats, PLoS One, 6, 10.1371/journal.pone.0024263
Yau, 2014, Physical exercise-induced hippocampal neurogenesis and antidepressant effects are mediated by the adipocyte hormone adiponectin, Proceedings of the National Academy of Sciences of the United States of America, 111, 15810, 10.1073/pnas.1415219111
Yin, 2018, Decreased cerebral blood flow in the primary motor cortex in major depressive disorder with psychomotor retardation, Progress in Neuro-Psychopharmacology & Biological Psychiatry, 81, 438, 10.1016/j.pnpbp.2017.08.013
Yu, 2017, Systematic review and meta-analysis of randomized, controlled trials on the effect of exercise on serum leptin and adiponectin in overweight and obese individuals, Hormone and Metabolic Research, 49, 164, 10.1055/s-0042-121605
Zhao, 2015, Treadmill exercise enhances synaptic plasticity, but does not alter beta-amyloid deposition in hippocampi of aged APP/PS1 transgenic mice, Neuroscience, 298, 357, 10.1016/j.neuroscience.2015.04.038