Exendin-4 promotes the vascular smooth muscle cell re-differentiation through AMPK/SIRT1/FOXO3a signaling pathways

Atherosclerosis - Tập 276 - Trang 58-66 - 2018
Zihan Liu1,2, Mengqian Zhang1,2, Tengfei Zhou1,2, Qiang Shen1,2, Xiaomei Qin1,2
1Institute of Cardiovascular Science, Beijing, 100191, China
2Key Laboratory of Molecular Cardiovascular Science of Ministry of Education, Peking University Health Science Center, Beijing, 100191, China

Tài liệu tham khảo

Libby, 2011, Progress and challenges in translating the biology of atherosclerosis, Nature, 473, 317, 10.1038/nature10146 Tabas, 2015, Recent insights into the cellular biology of atherosclerosis, J. Cell Biol., 209, 13, 10.1083/jcb.201412052 Kumar, 2003, Combinatorial control of smooth muscle-specific gene expression, Arterioscler. Thromb. Vasc. Biol., 23, 737, 10.1161/01.ATV.0000065197.07635.BA Gomez, 2012, Smooth muscle cell phenotypic switching in atherosclerosis, Cardiovasc. Res., 95, 156, 10.1093/cvr/cvs115 Zhao, 2014, Exendin-4 alleviates angiotensin II-induced senescence in vascular smooth muscle cells by inhibiting Rac1 activation via a cAMP/PKA-dependent pathway, Am. J. Physiol. Cell Physiol., 307, C1130, 10.1152/ajpcell.00151.2014 Goke, 1993, Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells, J. Biol. Chem., 268, 19650, 10.1016/S0021-9258(19)36565-2 Ueda, 2010, Identification of glycosylated exendin-4 analogue with prolonged blood glucose-lowering activity through glycosylation scanning substitution, Bioorg. Med. Chem. Lett, 20, 4631, 10.1016/j.bmcl.2010.06.002 Kieffer, 1995, Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV, Endocrinology, 136, 3585, 10.1210/endo.136.8.7628397 Mentlein, 1993, Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum, Eur. J. Biochem., 214, 829, 10.1111/j.1432-1033.1993.tb17986.x Ussher, 2014, Cardiovascular actions of incretin-based therapies, Circ. Res., 114, 1788, 10.1161/CIRCRESAHA.114.301958 Goto, 2011, Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces intimal thickening after vascular injury, Biochem. Biophys. Res. Commun., 405, 79, 10.1016/j.bbrc.2010.12.131 Zhou, 2016, Activation of Nrf2 contributes to the protective effect of Exendin-4 against angiotensin II-induced vascular smooth muscle cell senescence, Am. J. Physiol. Cell Physiol., 311, C572, 10.1152/ajpcell.00093.2016 Kassem, 2016, Exendin-4 enhances the differentiation of Wharton's jelly mesenchymal stem cells into insulin-producing cells through activation of various beta-cell markers, Stem Cell Res. Ther., 7, 108, 10.1186/s13287-016-0374-4 Nejad-Dehbashi, 2014, The effects of exendine-4 on insulin producing cell differentiation from rat bone marrow-derived mesenchymal stem cells, Cell J, 16, 187 Luciani, 2010, Differentiating effects of the glucagon-like peptide-1 analogue exendin-4 in a human neuronal cell model, Cell. Mol. Life Sci., 67, 3711, 10.1007/s00018-010-0398-3 Perry, 2002, A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells, J. Pharmacol. Exp. Therapeut., 300, 958, 10.1124/jpet.300.3.958 Xiao-Yun, 2011, Glucagon-like peptide-1 improves proliferation and differentiation of endothelial progenitor cells via upregulating VEGF generation, Med. Sci. Mon. Int. Med. J. Exp. Clin. Res., 17 Finkel, 2009, Recent progress in the biology and physiology of sirtuins, Nature, 460, 587, 10.1038/nature08197 Lan, 2008, SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation, J. Biol. Chem., 283, 27628, 10.1074/jbc.M805711200 Canto, 2009, AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity, Nature, 458, 1056, 10.1038/nature07813 Horio, 2011, Cellular and molecular effects of sirtuins in health and disease, Clin. Sci. (Lond.), 121, 191, 10.1042/CS20100587 Tang, 2008, Suppression of c-Cbl tyrosine phosphorylation inhibits neointimal formation in balloon-injured rat arteries, Circulation, 118, 764, 10.1161/CIRCULATIONAHA.107.761932 Qin, 2007, Laminar shear stress up-regulates the expression of stearoyl-CoA desaturase-1 in vascular endothelial cells, Cardiovasc. Res., 74, 506, 10.1016/j.cardiores.2007.02.014 Li, 2015, Exendin-4 promotes endothelial barrier enhancement via PKA- and Epac1-dependent Rac1 activation, Am. J. Physiol. Cell Physiol., 308, C164, 10.1152/ajpcell.00249.2014 Su, 2001, Redox regulation of vascular smooth muscle cell differentiation, Circ. Res., 89, 39, 10.1161/hh1301.093615 Tang, 2012, Histone deacetylase activity selectively regulates notch-mediated smooth muscle differentiation in human vascular cells, J Am Heart Assoc, 1 Chen, 2011, Cilostazol promotes vascular smooth muscles cell differentiation through the cAMP response element-binding protein-dependent pathway, Arterioscler. Thromb. Vasc. Biol., 31, 2106, 10.1161/ATVBAHA.111.230987 Li, 2008, AMP-activated protein kinase promotes the differentiation of endothelial progenitor cells, Arterioscler. Thromb. Vasc. Biol., 28, 1789, 10.1161/ATVBAHA.108.172452 Tashiro, 2014, A glucagon-like peptide-1 analog liraglutide suppresses macrophage foam cell formation and atherosclerosis, Peptides, 54, 19, 10.1016/j.peptides.2013.12.015 Hardie, 2011, AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function, Genes Dev., 25, 1895, 10.1101/gad.17420111 Correia, 2017, Sirtuins in metabolism, stemness and differentiation, Biochim. Biophys. Acta, 1861, 3444, 10.1016/j.bbagen.2016.09.008 Huang, 2015, SIRT1 and FOXO mediate contractile differentiation of vascular smooth muscle cells under cyclic stretch, Cell. Physiol. Biochem., 37, 1817, 10.1159/000438544 Abid, 2005, Forkhead transcription factors inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia, J. Biol. Chem., 280, 29864, 10.1074/jbc.M502149200 Lalmansingh, 2012, Multiple modes of chromatin remodeling by Forkhead box proteins, Biochim. Biophys. Acta, 1819, 707, 10.1016/j.bbagrm.2012.02.018 Mattagajasingh, 2007, SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase, Proc. Natl. Acad. Sci. U. S. A., 104, 14855, 10.1073/pnas.0704329104 Lim, 2017, Attenuation of carotid neointimal formation after direct delivery of a recombinant adenovirus expressing glucagon-like peptide-1 in diabetic rats, Cardiovasc. Res., 113, 183, 10.1093/cvr/cvw213 Piotrowski, 2013, Circulating concentrations of GLP-1 are associated with coronary atherosclerosis in humans, Cardiovasc. Diabetol., 16, 117, 10.1186/1475-2840-12-117 Yamaoka-Tojo, 2010, Elevated circulating levels of an incretin hormone, glucagon-like peptide-1, are associated with metabolic components in high-risk patients with cardiovascular disease, Cardiovasc. Diabetol., 9, 17, 10.1186/1475-2840-9-17 Sudo, 2017, Inhibition of plaque progression and promotion of plaque stability by glucagon-like peptide-1 receptor agonist: serial in vivo findings from iMap-IVUS in Watanabe heritable hyperlipidemic rabbits, Atherosclerosis, 265, 283, 10.1016/j.atherosclerosis.2017.06.920