Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells.

Journal of Biological Chemistry - Tập 268 Số 26 - Trang 19650-19655 - 1993
Rüdiger Göke1, Hans-Christoph Fehmann1, Thomas Linn1, Harald Schmidt1, Michael Krause1, John Eng1, Burkhard Göke1
1Department of Internal Medicine, Philipps-University of Marburg, Germany

Tóm tắt

Từ khóa


Tài liệu tham khảo

Zunz, 1929, Arch. Int. Physiol. Biochim., 31, 20

Creutzfeldt, 1979, Diabetologia, 16, 75, 10.1007/BF01225454

Göke, 1991, Eur. J. Clin. Invest., 21, 135, 10.1111/j.1365-2362.1991.tb01802.x

Fehmann, 1992, Mol. Cell. Endocrinol., 85, C39, 10.1016/0303-7207(92)90118-P

Fehmann, 1992, Trends Endocrinol. Metab., 3, 158, 10.1016/1043-2760(92)90165-W

Göke, 1988, J. Endocrinol., 116, 357, 10.1677/joe.0.1160357

Göke, 1989, J. Mol. Endocrinol., 2, 93, 10.1677/jme.0.0020093

Göke, 1992, FEES Lett., 300, 232, 10.1016/0014-5793(92)80852-8

Thorens, 1992, Proc. Natl. Acad. Sci. U. S. A., 89, 8641, 10.1073/pnas.89.18.8641

Fehmann, 1991, Int. J. Pancreatol., 8, 289, 10.1007/BF02952722

Parker, 1984, J. Biol. Chem., 259, 11751, 10.1016/S0021-9258(20)71275-5

Vandermeers, 1984, FEBS Lett., 166, 273, 10.1016/0014-5793(84)80094-0

Eng, 1990, J. Biol. Chem., 265, 20259, 10.1016/S0021-9258(17)30498-2

Eng, 1992, J. Biol. Chem., 267, 7402, 10.1016/S0021-9258(18)42531-8

Raufman, 1991, J. Biol. Chem., 266, 2897, 10.1016/S0021-9258(18)49932-2

Raufman, 1992, J. Biol. Chem., 267, 21432, 10.1016/S0021-9258(19)36628-1

Eng, 1992, Regul. Pept., 40, 142, 10.1016/0167-0115(92)90201-5

Wollheim, 1984, J. Biol. Chem., 259, 2262, 10.1016/S0021-9258(17)43347-3

Richter, 1990, FEBS Lett., 267, 78, 10.1016/0014-5793(90)80292-Q

Richter, 1991, FEBS Lett., 280, 247, 10.1016/0014-5793(91)80303-K

Göke, 1993, Am. J. Physiol, 264, L146, 10.1152/ajpcell.1993.264.1.C146

Richter, 1993, Am. J. Physiol.

Praz, 1983, Biochem. J., 210, 345, 10.1042/bj2100345

Bradford, 1976, Anal. Biochem., 72, 248, 10.1016/0003-2697(76)90527-3

Laemmli, 1970, Nature, 227, 680, 10.1038/227680a0

Gotoh, 1985, Transplantation, 40, 437, 10.1097/00007890-198510000-00018

Fehmann, 1992, Endocrinology, 130, 159, 10.1210/endo.130.1.1309325

Eissele, 1992, Eur. J. Clin. Invest., 22, 283, 10.1111/j.1365-2362.1992.tb01464.x

Holz, 1993, Nature, 361, 362, 10.1038/361362a0

Nauck, 1993, J. Clin. Invest., 30, 301, 10.1172/JCI116186

Gutniak, 1992, N. Engl. J. Med., 326, 1316, 10.1056/NEJM199205143262003