Ex vivo porcine model for eye, eyelid, and orbit movement analysis of 4-mm ferromagnetic foreign bodies in MRI
Tóm tắt
Ferromagnetic foreign bodies (FFB) present during magnetic resonance imaging (MRI) explorations can lead to tissue injury due to movement, especially in and around the eyes. Ferromagnetic foreign bodies located in the intraocular area, eyelids, and orbit are thus prohibited from undergoing MRI. The aim of the study was to analyze movement of 4-mm ferromagnetic foreign bodies in MRI in the eye, eyelid, and orbit using computed tomography (CT) scan. We developed a porcine model using 12 quarters of fresh porcine heads. Each porcine head included one whole orbit with the ocular globe, orbital fat, muscles, and eyelids. Four-millimeter FFB were implanted in the eye within 2 days post-slaughter, and images were acquired within 5 days post-slaughter. Four-millimeter FFB movement was analyzed after 1.5-Tesla (T) MRI. Four locations were tested: intravitreous, suprachoroidal, intraorbital fat, and intrapalpebral. Movement analysis was assessed using computed tomography (CT) scan. The intravitreous ferromagnetic ball moved 14.0 ± 8.8 mm (p < 0.01), the suprachoroidal ball moved 16.8 ± 5.4 mm (p < 0.01), the intraorbital fat ball moved 5.8 ± 0.9 mm (p > 0.05), and the intrapalpebral ball moved 2.0 ± 0.4 mm (p > 0.05). The ex vivo porcine model was able to study FFB movement. The 4-mm ferromagnetic balls moved in intravitreous and in suprachoroidal locations after MRI.
Tài liệu tham khảo
Detournay. B, Courouve. L (2017). Les insuffisances en matière d’équipement d’imagerie médicale en France. http://www.sfrnet.org/rc/org/sfrnet/htm/Article/2015/20150625-083932-499/src/htm_fullText/fr/2015-014%20ISA%20IRM%20Rapport%2013-05-15.pdf
Schenck JF (2000) Safety of strong, static magnetic fields. J Magn Reson Imaging 12:2–19
Lagouros PA et al (1987) Magnetic resonance imaging and intraocular foreign bodies. Arch Ophthalmol 105:551–553
Williams S, Char DH, Dillon WP, Lincoff N, Moseley M (1988) Ferrous intraocular foreign bodies and magnetic resonance imaging. Am J Ophthalmol 105:398–401
Williamson TH, Smith FW, Forrester JV (1989) Magnetic resonance imaging of intraocular foreign bodies. Br J Ophthalmol 73:555–558
Gunenc U, Ahmet M, Suleyman K, Tugrul P (1992) Magnetic resonance imaging and computed tomography in the detection and localization of intra ocular foreign bodies. Documentia Ophtalmologica 81:369–378. https://doi.org/10.1007/BF00169098
Cullen C, Kendall E, Cui J, Colleaux K, Grahn B (2002) The effects of exposure to a 1.5-tesla magnetic field on intravitreous metallic foreign bodies in rabbits. Graefes Arch Clin Exp Ophthalmol 240:393–402
Duratool (2014) 450 piece steel Ball Assortment V1.0 2057 https://cpc.farnell.com/duratool/d01897/steel-ball-assortment-450pc/dp/FN02654#anchorTechnicalDOCS
Yushkevich PA et al (2006) User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability. NeuroImage 31:1116–1128
Lawrence DA, Lipman AT, Gupta SK, Nacey NC (2015) Undetected intraocular metallic foreign body causing hyphema in a patient undergoing MRI: a rare occurrence demonstrating the limitations of pre-MRI safety screening. Magn Reson Imaging 33:358–361
Platt AS, Wajda BG, Ingram AD, Wei X-C, Ells AL (2017) Metallic intraocular foreign body as detected by magnetic resonance imaging without complications– a case report. Am J Ophthalmol Case Reports 7:76–79
Fernandez-Bueno I, Pastor JC, Gayoso M, Alcalde I (2008) Müller and macrophage-like cell interactions in an organotypic culture of porcine neuroretina. Mol Vis 14:2148–2156
Ruiz-Ederra J et al (2005) The pig eye as a novel model of glaucoma. Exp Eye Res 81:561–569
Nishi O, Nishi K, Nishi Y, Chang S (2008) Capsular bag refilling using a new accommodating intraocular lens. J Cataract Refract Surg 34:302–309
Olsen TW, Sanderson S, Feng X, Hubbard WC (2002) Porcine sclera: thickness and surface area. IOVS Investigative Ophthalmology & Visual Science 43:4
Swindle KE, Hamilton PD, Ravi N (2008) In situ formation of hydrogels as vitreous substitutes: viscoelastic comparison to porcine vitreous. J Biomed Mater Res 87A:656–665
Gor DM, Kirsch CF, Leen J, Turbin R, Von Hagen S (2001) Radiologic differentiation of intraocular glass: evaluation of imaging techniques, glass types, size, and effect of intraocular hemorrhage. Am J Roentgenol 177:1199–1203
Shellock FG (2000) Radiofrequency energy-induced heating during MR procedures: a review. J Magn Reson Imaging 12:30–36