Evolving Concepts of Keystone Perforator Island Flaps (KPIF): Principles of Perforator Anatomy, Design Modifications, and Extended Clinical Applications

Plastic and Reconstructive Surgery - Tập 137 Số 6 - Trang 1909-1920 - 2016
Anita T. Mohan1,2,3, Charalambos K. Rammos1,2,3, Arya A. Akhavan1,2,3, Jorys Martinez1,2,3, Peter Wu1,2,3, Steven L. Moran1,2,3, Franklin H. Sim1,2,3, Felix Behan1,2,3, Samir Mardini1,2,3, Michel Saint‐Cyr1,2,3
1Australia
2Kingdom
3Minn.

Tóm tắt

Background:

Keystone flaps have demonstrated growing clinical applications in reconstructive surgery in the past decade. This article highlights flap modifications and their versatility for clinical applications and management of complex defects.

Methods:

A retrospective chart review was conducted of consecutive patients undergoing keystone flap reconstruction at the authors’ institution from January of 2012 to December of 2014. Patient demographics, indications, and operative and postoperative details were abstracted.

Results:

Forty-two keystone flaps were performed in 36 patients. Indications included malignant melanoma (n = 14), soft-tissue sarcoma (n = 12), benign pathologic conditions (e.g., exposed hardware, enterocutaneous fistula, tissue necrosis) (n = 6), and nonmelanoma skin cancer (n = 4). Twenty-eight percent received neoadjuvant irradiation, and 70 percent of these were for sarcoma. Locoregional adjunct flaps were performed in eight patients. The deep fascia was nearly completely in a circumferential manner in 18 of 36 patients (50 percent), in 92 percent of the sarcoma reconstructions, and located mainly in the lower extremity. Average defect size was 215 cm2 (range, 4 to 1000 cm2). Average defect size was 474 cm2 and 35.8 cm2 after sarcoma and malignant melanoma resection, respectively. Average flap size was 344 cm2 (range, 5 to 1350 cm2). Ninety percent of cases had flap sizes exceeding the traditional 1:1 ratio. There was no flap loss or partial necrosis. Mean time to mobilization was 1.8 days, and mean hospital length of stay was 6.8 days.

Conclusions:

Keystone flaps offer an excellent versatile tool for reconstructive surgeons. Fundamental principles behind the vascular basis of the keystone flap and its modifications permit their greater utility in complex wounds in the settings of large oncologic resections, irradiation, and trauma.

CLINICAL QUESTION/LEVEL OF EVIDENCE:

Therapeutic, IV.

Từ khóa


Tài liệu tham khảo

Saint-Cyr, 2011, Assessing perforator architecture., Clin Plast Surg, 38, 175, 10.1016/j.cps.2011.03.015

Saint-Cyr, 2009, The perforasome theory: Vascular anatomy and clinical implications., Plast Reconstr Surg, 124, 1529, 10.1097/PRS.0b013e3181b98a6c

Taylor, 1987, The vascular territories (angiosomes) of the body: Experimental study and clinical applications., Br J Plast Surg, 40, 113, 10.1016/0007-1226(87)90185-8

Morris, 2010, The anatomic basis of perforator flaps., Clin Plast Surg, 37, 553, 10.1016/j.cps.2010.06.006

Laungani, 2015, Three-dimensional CT angiography assessment of the impact of the dermis and the subdermal plexus in DIEP flap perfusion., J Plast Reconstr Aesthet Surg, 68, 525, 10.1016/j.bjps.2014.12.004

Geddes, 2003, Perforator flaps: Evolution, classification, and applications., Ann Plast Surg, 50, 90, 10.1097/00000637-200301000-00016

Behan, 2003, The keystone design perforator island flap in reconstructive surgery., ANZ J Surg, 73, 112, 10.1046/j.1445-2197.2003.02638.x

Behan, 2009, Perforator territory of the keystone flap: Use of the dermatomal roadmap., J Plast Reconstr Aesthet Surg, 62, 551, 10.1016/j.bjps.2008.08.078

Khouri, 2011, The keystone island flap: Use in large defects of the trunk and extremities in soft-tissue reconstruction., Plast Reconstr Surg, 127, 1212, 10.1097/PRS.0b013e318205f36f

Saint-Cyr, 2009, Perforator flaps: History, controversies, physiology, anatomy, and use in reconstruction., Plast Reconstr Surg, 4, 132e, 10.1097/PRS.0b013e31819f2c6a

Hu, 2012, The keystone flap for lower extremity defects., Dermatol Surg, 38, 490, 10.1111/j.1524-4725.2011.02236.x

Martinez, 2012, The keystone fasciocutaneous flap in the reconstruction of lower extremity wounds., Dermatol Surg, 38, 484, 10.1111/j.1524-4725.2011.02239.x

Behan, 2012, ‘Perineal keystone design perforator island flap’ for perineal and vulval reconstruction., ANZ J Surg, 82, 381, 10.1111/j.1445-2197.2012.06021.x

Milton, 1971, Experimental studies on island flaps: 1. The surviving length., Plast Reconstr Surg, 48, 574, 10.1097/00006534-197112000-00009

Behan, 2008, Evolution of the fasciocutaneous island flap leading to the keystone flap principle in lower limb reconstruction., ANZ J Surg, 78, 116, 10.1111/j.1445-2197.2007.04382.x

Behan, 1992, The fasciocutaneous island flap: An extension of the angiotome concept., Aust N Z J Surg, 62, 874, 10.1111/j.1445-2197.1992.tb06943.x

Saint-Cyr, 2009, The extended anterolateral thigh flap: Anatomical basis and clinical experience., Plast Reconstr Surg, 123, 1245, 10.1097/PRS.0b013e31819e2718

Monarca, 2012, Keystone flap: Freestyle technique to enhance the mobility of the flap [corrected]., ANZ J Surg, 82, 950, 10.1111/j.1445-2197.2012.06299.x

Moncrieff, 2008, Keystone flap reconstruction of primary melanoma excision defects of the leg: The end of the skin graft?, Ann Surg Oncol, 15, 2867, 10.1245/s10434-008-0018-8

Behan, 2006, Keystone island flap: An alternative reconstructive option to free flaps in irradiated tissue., ANZ J Surg, 76, 407, 10.1111/j.1445-2197.2006.03708.x

Behan, 2013, Quadriceps keystone island flap for radical inguinal lymphadenectomy: A reliable locoregional island flap for large groin defects., ANZ J Surg, 83, 942, 10.1111/j.1445-2197.2011.05790.x

Shayan, 2013, Re: The “keystone concept”: Time for some science., ANZ J Surg, 83, 499, 10.1111/ans.12303

Pelissier, 2007, The keystone design perforator island flap: Part I. Anatomic study., J Plast Reconstr Aesthet Surg, 60, 883, 10.1016/j.bjps.2007.01.072

Rao, 2015, Keystone flap: Versatile flap for reconstruction of limb defects., J Clin Diagn Res, 9, PC05

Gutman, 2011, Keystone design perforator island flap for closure of myelomeningocele., Childs Nerv Syst, 27, 1459, 10.1007/s00381-011-1448-3

Behan, 2010, Use of the keystone island flap for advanced head and neck cancer in the elderly: A principle of amelioration., J Plast Reconstr Aesthet Surg, 63, 739, 10.1016/j.bjps.2009.01.079

Behan, 2011, Yin-yang flaps: The mathematics of two keystone island flaps for reconstructing increasingly large defects., ANZ J Surg, 81, 574, 10.1111/j.1445-2197.2011.05814.x

Behan, 2011, The omega - Ω - variant designs (types A and B) of the keystone perforator island flap., ANZ J Surg, 81, 650, 10.1111/j.1445-2197.2011.05833.x