Evolutionary aspects of peroxisomes as cell organelles, and of genes encoding peroxisomal proteins

Biology of the Cell - Tập 92 - Trang 389-395 - 2000
Norbert Latruffe1, Joseph Vamecq2
1Université de Bourgogne, LBMC, 6 boulevard Gabriel, 21000 Dijon, France
2Inserm/département de neuropédiatrie, CHU Lille, 2 avenue Oscar-Lambret, 59037 Lille, France

Tóm tắt

Peroxisomes are present in most eukaryotic cell types, and have different enzymatic content and metabolic functions throughout the life scale. The endosymbiotic origin of these DNA‐devoid organelles is supported by evolutionary data concerning genes encoding not only most peroxisomal proteins, but also several transcriptional factors regulating their expression such as peroxisome proliferator‐activated receptors.