Everolimus for the treatment of advanced, non-functional neuroendocrine tumours of the lung or gastrointestinal tract (RADIANT-4): a randomised, placebo-controlled, phase 3 study

The Lancet - Tập 387 Số 10022 - Trang 968-977 - 2016
James C. Yao1, Nicola Fazio2, Simron Singh3, Roberto Buzzoni4, Carlo Carnaghi5, Edward M. Wolin6, Jiří Tomášek7, Markus Raderer8, Harald Lahner9, Maurizio Voi10, Lida Pacaud11, Nicolas Rouyrre11, Carolin Sachs11, Juan W. Valle12, Gianfranco Delle Fave13, Eric Van Cutsem14, Margot E. T. Tesselaar15, Yasuhiro Shimada16, Do‐Youn Oh17, Jonathan Strosberg18, Matthew H. Kulke19, Marianne Pavel20
1University of Texas/MD Anderson Cancer Center, Houston, TX USA
2Istituto Europeo di Oncologia, IRCCS, Milan, Italy
3Sunnybrook Health Sciences Centre, Toronto, ON, Canada
4Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
5IRCCS Istituto Clinico Humanitas, Rozzano, Italy
6Markey Cancer Center, University of Kentucky, Lexington, KY, USA
7Masaryk Memorial Cancer Institute, Faculty of Medicine, Masaryk University, Brno, Czech Republic
8Univ. Klinik f. Innere Medizin I, AKH, Vienna, Austria
9Universitaetsklinikum Essen, Zentrum f. Innere Medizin, Essen, Germany
10Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA
11Novartis Pharma AG, Basel, Switzerland
12Institute of Cancer Studies, University of Manchester, The Christie Hospital, Manchester, UK
13Azienda Ospedaliera Sant'Andrea, Università La Sapienza, Rome, Italy
14University Hospitals Gasthuisberg Leuven and KU Leuven, Leuven, Belgium
15Nederlands Kanker Instituut, Antoni van Leeuwenhoek, Amsterdam, Netherlands
16National Cancer Center Hospital, Tokyo, Japan
17Seoul National University Hospital, Seoul, South Korea
18Moffitt Cancer Center, Tampa, FL, USA
19Dana Farber Cancer Institute, Boston, MA, USA
20Charité, Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany

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