Evaluation of the Efficacy of Four Feed Additives Against the Adverse Effects of T-2 Toxin in Growing Broiler Chickens

Leeson, 1995, Trichothecenes, 190 Bauer, 1989, Metabolism of the trichothecenes T-2 toxin, diacetoxyscirpenol, and deoxynivalenol by farm animals, 139 Diaz, 1994, Individual and combined effects of T-2 toxin and DAS in laying hens, Br. Poult. Sci., 35, 393, 10.1080/00071669408417704 Kubena, 1990, Efficacy of a hydrated sodium calcium aluminosilicate to reduce the toxicity of aflatoxin and T-2 toxin, Poult. Sci., 69, 1078, 10.3382/ps.0691078 Kubena, 1993, Efficacy of a hydrated sodium calcium aluminosilicate to reduce the toxicity of aflatoxin and diacetoxiscirpenol, Poult. Sci., 72, 51, 10.3382/ps.0720051 Phillips, 1999, Dietary clay in the chemoprevention of aflatoxin-induced disease, Toxicol. Sci., 52, 118, 10.1093/toxsci/52.suppl_1.118 Aravind, 2003, Efficacy of esterified glucomannan to counteract mycotoxicosis in naturally contaminated feed on performance and serum biochemical and hematological parameters in broilers, Poult. Sci., 82, 571, 10.1093/ps/82.4.571 Ehrlich, 1987, Protein synthesis inhibition by 8-oxo-12,13-epoxytrichothecenes, Biochim. Biophys. Acta, 923, 206, 10.1016/0304-4165(87)90005-5 Binder, E. M., D. Heidler, G. Schatzmayr, N. Thimm, E. Fuchs, R. Krska, and J. Binder. 2000. Microbial detoxification of mycotoxins in animal feed. Pages 21–25 in Proceedings of the 10th Int. IUPAC Symp. Mycotoxins and Phycotoxins, São Paulo, Brazil. Mycofix, Biomin Innovative Animal Nutrition GmbH, Herzogenburg, Austria; Mycosorb, Alltech, Inc., Lexington, Kentucky; MycoAd, Special Nutrients, Inc., Miami, Florida; and Zeolex, Nutrimix, Coyoacán, Mexico. Burmeister, 1971, T-2 toxin production by Fusarium tricinctum in solid substrate, Appl. Microbiol., 21, 739, 10.1128/AEM.21.4.739-742.1971 Lumeij, 1997, Avian clinical biochemistry, 857 Diaz, 1999, The use of selected plasma enzyme activities for the diagnosis of fatty-liver hemorrhagic syndrome in laying hens, Avian Dis., 43, 768, 10.2307/1592746 Statistical analysis. Data (pen means) for all response variables were subjected to ANOVA for a complete randomized design, using Statistix for Windows version 2.0(1998). The main effect was treatment within each week or treatment during the 28-d experimental period. Error was estimated from variation among pens. Variables showing unequal variances according to Bartlett's test (P< 0.05) were analyzed using Kriskal-Wallis 1-way nonparametric ANOVA. Variable means from treatments showing significant differences in the ANOVA were compared using the least significance difference method. Statements of significance are based on P = 0.05 [17]. Diaz, 2002, Evaluation of the efficacy of a feed additive to ameliorate the toxic effects of 4,15-diacetoxiscirpenol in growing chicks, Poult. Sci., 81, 1492, 10.1093/ps/81.10.1492 Diaz, 2001, Naturally occurring toxins relevant to poultry nutrition, 544 Statistix for Windows, 1998