Evaluation of the C3435T polymorphism in the MDR1 gene in patients with hepatocellular carcinoma

El-Serag, 2007, Hepatocellular carcinoma: epidemiology and molecular carcinogenesis, Gastroenterology, 132, 2557, 10.1053/j.gastro.2007.04.061 Roberts, 2008, Sorafenib in liver cancer-Just the beginning, N Engl J Med, 359, 420, 10.1056/NEJMe0802241 Llovet, 2008, Design and endpoints of clinical trials in hepatocellular carcinoma, J Natl Cancer Inst, 100, 698, 10.1093/jnci/djn134 Bruix, 2011, Management of hepatocellular carcinoma: An update, Hepatology, 53, 1020, 10.1002/hep.24199 Llovet, 2008, Sorafenib in advanced hepatocellular carcinoma, N Engl J Med, 359, 378, 10.1056/NEJMoa0708857 Brose, 2000, Genetic predisposition to cancer-cancer etiology., Cancer Medicine., 168 The Human Genome. Disponível em: http://genome.wellcome.ac.uk/ [Acesso em: 28 de Março de 2011]. Gottesman, 1993, Biochemistry of multidrug resistance mediated by the multidrug transporter, Annu Rev Biochem, 62, 385, 10.1146/annurev.bi.62.070193.002125 Gottesman, 2002, Multidrug resistance in cancer: role of ATP-dependent transporters, Nat Rev Cancer, 2, 48, 10.1038/nrc706 Huang, 2011, Influence of MDR1 gene C3435T on peripheral white blood cell counts in workers exposed to benzene, Chi J Ind Hyg Oceup Dis, 2, 20 Hoffmeyer, 2000, Functional polymorphisms of the human multidrug resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo, Proc Natl Acad Sci, 97, 3473, 10.1073/pnas.97.7.3473 Leslie, 2005, Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2 and BCRP (ABCG2) in tissue defense, Toxicol Appl Pharmacol, 204, 216, 10.1016/j.taap.2004.10.012 Jamroziak, 2004, Functional C3435T polymorphism of MDR1 gene: an impact on genetic susceptibility and clinical outcome of childhood acute lymphoblastic leukemia, Eur J Haemato, 72, 314, 10.1111/j.1600-0609.2004.00228.x Gervasini, 2006, Adenosine triphosphate-binding cassette B1 (ABCB1) (multidrug resistance 1) G2677T=A gene polymorphism is associated with high risk of lung cancer, Cancer, 107, 2850, 10.1002/cncr.22332 Sauna, 2001, The mechanism of action of multi-drug-resistance-linked P-glycoprotein, J Bioenerg Biomembr, 33, 481, 10.1023/A:1012875105006 Avendano, 2002, Inhibitors of multidrug resistance to antitumor agents (MDR), Curr Med Chem, 9, 159, 10.2174/0929867023371175 Fromm, 2002, Genetically determined differences in P-glycoprotein function: Implications for disease risk, Toxicology, 182, 299, 10.1016/S0300-483X(02)00297-4 Baekelandt, 2000, P-glycoprotein expression is a marker for chemo therapy resistance and prognosis in advanced ovarian cancer, Anticancer Res, 20, 1061 Alves, 2008, Osteossarcomas humanos de alto grau: imunoexpressão de p53, erb-2 e P-glicoproteína, e correlação com o parâmetro anaplasia, J Bras Patol Med Lab, 44, 107, 10.1590/S1676-24442008000200007 Sjöholm, 2005, Comparison of archival plasma and formalin-fixed paraffin-embedded tissue for genotyping in hepatocellular carcinoma, Cancer Epidemiol Biomarkers Prev, 14, 251, 10.1158/1055-9965.251.14.1 Silva, 2008, Evaluation of hepatic resection for hepatocellular carcinoma on cirrhotic livers, Arq Gastroenterol, 45, 99, 10.1590/S0004-28032008000200002 Fassio, 2010, Etiology of hepatocellular carcinoma in Latin America: a prospective, multicenter, international study, Ann Hepatol, 1, 63, 10.1016/S1665-2681(19)31681-3 Huang, 1992, Overexpression of the MDR1 gene and P-glycoprotein in human hepatocellular carcinoma, J Natl Cancer Inst, 84, 262, 10.1093/jnci/84.4.262 Turgut, 2007, MDR1 C3435T polymorphism in patients with breast cancer, Arch Med Res, 38, 539, 10.1016/j.arcmed.2007.02.005 Taheri, 2010, Effect of MDR1 polymorphism on multidrug resistance expression in breast cancer patients., Genet Mol Res, 12, 34, 10.4238/vol9-1gmr669 Siegsmund, 2002, Association of the P-glycoprotein transporter MDR1 (C3435T) polymorphism with the susceptibility to renal epithelial tumors, J Am Soc Nephrol, 13, 1847, 10.1097/01.ASN.0000019412.87412.BC Farnood, 2007, The frequency of C3435T MDR1 gene polymorphism in Iranian patients with ulcerative colitis, Int J Colorectal Dis, 22, 999, 10.1007/s00384-007-0270-6 Owen, 2005, Relationship between the C3435T and G2677T(A) polymorphisms in the ABCB1 gene and P-glycoprotein expression in human liver, Br J Clin Pharmacol, 59, 365, 10.1111/j.1365-2125.2005.02229.x Wu, 2007, MDR1 gene polymorphisms and risk of recurrence in patients with hepatocellular carcinoma after liver transplantation, J Surg Oncol, 96, 62, 10.1002/jso.20774 Sun, 2010, Relevance of two genes in the multidrug resistance of hepatocellular carcinoma: in vivo and clinical studies, Tumori, 96, 90, 10.1177/030089161009600115 Wang, 2005, Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435>T affects mRNA stability., Pharmacogenet Genomics, 15, 693, 10.1097/01.fpc.0000178311.02878.83