Evaluation of serum levels of IL-6, TNF-α, IL-10, IL-2 and IL-4 in patients with chronic hepatitis

Inmunología - Tập 33 - Trang 41-50 - 2014
Antonia Mourtzikou1,2, Maria Alepaki1, Marilena Stamouli3, Abraham Pouliakis1, Anastasios Skliris3, Petros Karakitsos1
1Department of Cytopathology, Attikon University Hospital, Athens, Greece
2Department of Biochemistry, Asklepieio Voulas General Hospital, Athens, Greece
3Department of Biochemistry, Naval and Veterans Hospital, Athens, Greece

Tài liệu tham khảo

Ott, 2012, Global epidemiology of hepatitis B virus infection: new estimates of age-specific HBsAg seroprevalence and endemicity, Vaccine, 30, 2212, 10.1016/j.vaccine.2011.12.116 Lavanchy, 2004, Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures, J Viral Hepat, 11, 97, 10.1046/j.1365-2893.2003.00487.x McMahon, 2005, Epidemiology and natural history of hepatitis B, Semin Liver Dis, 25, 3, 10.1055/s-2005-915644 Averhoff, 2012, Global burden of hepatitis C: considerations for healthcare providers in the United States, Clin Infect Dis, 55, S10, 10.1093/cid/cis361 Shepard, 2005, Global epidemiology of hepatitis C virus infection, Lancet Infect Dis, 5, 558, 10.1016/S1473-3099(05)70216-4 Lavanchy, 2009, The global burden of hepatitis C, Liver Int, 29, 74, 10.1111/j.1478-3231.2008.01934.x Pan, 2005, Natural history and clinical consequences of hepatitis B virus infection, Int J Med Sci, 2, 36, 10.7150/ijms.2.36 Chen, 2006, The natural history of hepatitis C (HCV) infection, Int J Med Sci, 3, 47, 10.7150/ijms.3.47 Reherman, 2005, Immunology of hepatitis B virus and hepatitis C virus infection, Nat Rev Immunol, 5, 215, 10.1038/nri1573 Jacobson Brown, 2001, Immunopathogenesis of hepatitis C viral infection: Th1/Th2 responses and the role of cytokines, Clin Biochem, 34, 167, 10.1016/S0009-9120(01)00210-7 Falasca, 2006, Cytokine patterns correlate with liver damage in patients with chronic hepatitis B and C, Ann Clin Lab Sci, 36, 144 Larrubia, 2009, Cytokines – their pathogenic and therapeutic role in chronic viral hepatitis, Rev Esp Enferm Dig, 101, 343, 10.4321/S1130-01082009000500006 Khan, 2011, Circulating biomarkers and their possible role in pathogenesis of chronic hepatitis B and C viral infections, Ind J Clin Biochem, 26, 161, 10.1007/s12291-010-0098-7 Priimägi, 2005, The role of serum Th1 and Th2 cytokines in patients with chronic hepatitis B and hepatitis C virus infection, Acta Medica Lituanica, 12, 28 Mishra, 2010, Mediators of the immune system and their possible role in pathogenesis of chronic hepatitis B and C viral infections, AsPac J Mol Biol Biotechnol, 18, 341 al_Sharif, 2011, Interleukins and chronic hepatitis, Middle East J Sci Res, 7, 1001 Bertoletti, 2006, The immune response during hepatitis B virus infection, J Gen Virol, 87, 1439, 10.1099/vir.0.81920-0 Wieland, 2005, Stealth and cunning: hepatitis B and hepatitis C viruses, J Virol, 79, 9369, 10.1128/JVI.79.15.9369-9380.2005 Iannacone, 2006, Pathogenetic and antiviral immune responses against hepatitis B virus, Future Virol, 1, 189, 10.2217/17460794.1.2.189 Sobchak, 2004, Immune parameters in patients with chronic hepatitis C and with various histologic changes, Klin Med (Mosk), 82, 49 Toumpanakis, 2007, Molecular mechanisms of action of interleukin-6 (IL-6), Pneumon, 2, 154 Rose-John, 2003, Interleukin-6 biology is coordinated by membrane bound and soluble receptors, Acta Biochim Pol, 50, 603, 10.18388/abp.2003_3654 Gabay, 2006, Interleukin-6 and chronic inflammation, Arthritis Res Ther, 8, S3, 10.1186/ar1917 Cronstein, 2007, Interleukin-6 – a key mediator of systemic and local symptoms in rheumatoid arthritis, Bull NYU Hosp Joint Dis, 65, S11 Soresi, 2006, Interleukin-6 and its soluble receptor in patients with liver cirrhosis and hepatocellular carcinoma, World J Gastroenterol, 12, 2563, 10.3748/wjg.v12.i16.2563 Abd EL-Ghaffar, 2008, Prognostic significance of interleukins determination in liver diseases research, J Med Med Sci, 3, 124 Wong, 2009, High serum interleukin-6 level predicts future hepatocellular carcinoma development in patients with chronic hepatitis B, Int J Cancer, 124, 2766, 10.1002/ijc.24281 Kuo, 2009, HBV replication is significantly reduced by IL-6, J Biomed Sci, 16, 41, 10.1186/1423-0127-16-41 Chen, 2010, Pegylated interferon α-2b up-regulates specific CD8+ T cells in patients with chronic hepatitis B, World J Gastroenterol, 16, 6145, 10.3748/wjg.v16.i48.6145 Lokhande MU, Miquel J, Benito S, Larrubia J-R. HBV & HCV Immunopathogenesis, Viral Hepatitis – Selected Issues of Pathogenesis and Diagnostics, Dr. Sergey Mukomolov (Ed.), ISBN: 978-953-307-760-4, InTech. Available from: http://www.intechopen.com/books/viralhepatitis-selected-issues-of-pathogenesis-and-diagnostics/hbv-hcv-immunopathogenesis. Gao, 2005, Cytokines, STATs and liver disease, Cell Mol Immunol, 2, 92 Zhang, 2011, Cytokine levels in serum of patients with chronic hepatitis C and its significance, Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 27, 301 Nakagawa H., 2009, Serum IL-6 levels and the risk for hepatocarcinogenesis in chronic hepatitis C patients: an analysis based on gender differences, Int J Cancer, 125, 2264, 10.1002/ijc.24720 Tangkijvanich, 2000, Serum interleukin-6 and interferon-gamma levels in patients with hepatitis B-associated chronic liver disease, Asian Pac J Allergy Immunol, 18, 109 Schwabe, 2006, Mechanisms of liver injury: TNF-a-induced liver injury: role of IKK, JNK, ROS pathways, Am J Physiol Gastrointest Liver Physiol, 290, G583, 10.1152/ajpgi.00422.2005 Wullaert A, van Loo G, Heyninck K, Beyaert R. Hepatic TNF signaling and NF-κB: effects on liver homeostasis and beyond. http://edrv.endojournals.org/content/early/2007/04/12/er. 2006-0031.full.pdf. Akpolat, 2005, Relationship between serum cytokine levels and histopathological changes of liver in patients with hepatitis B, World J Gastroenterol, 11, 3260, 10.3748/wjg.v11.i21.3260 Yia, 2003, Hepatitis B virus X protein induces TNF-a expression via down-regulation of selenoprotein P in human hepatoma cell line, HepG2, Biochim Biophys Acta, 1638, 249, 10.1016/S0925-4439(03)00090-5 Liu, 2011, Changes of IL-1, TNF-Alpha, IL-12 and IL-10 levels with chronic liver failure, Surg Sci, 2, 69, 10.4236/ss.2011.22015 Thio, 2004, An analysis of tumor necrosis factor a gene polymorphisms and haplotypes with natural clearance of hepatitis C virus infection, Genes Immun, 5, 294, 10.1038/sj.gene.6364072 Mogensen, 2001, Molecular pathways in virus-induced cytokine production, Microbiol Mol Biol Rev, 65, 131, 10.1128/MMBR.65.1.131-150.2001 Jeng, 2007, Tumor necrosis factor-A 308.2 polymorphism is associated with advanced hepatic fibrosis and higher risk for hepatocellular carcinoma, Neoplasia, 9, 987, 10.1593/neo.07781 Wang, 2003, Increased serum concentrations of tumor necrosis factor-alpha are associated with disease progression and malnutrition in hepatocellular carcinoma, J Chin Med Assoc, 66, 593 Astakhin, 2004, Tumor necrosis factor-alpha and interleukin-4 in the blood sera of chronic hepatitis patients, Zh Mikrobiol Epidemiol Immunobiol, 46 Loginov, 2001, Interleukins in chronic viral hepatitis, Ter Arkh, 73, 17 Helaly GF, Abou Shamaa LA. Tumor necrosis factor-alpha in hepatitis C virus infection: a correlation with viral activity and serum aminotransferases. Available at: http://ejimmunology.tripod.com/previous/jun02/jun02-10.htm. Moura, 2009, Soluble inflammatory markers as predictors of hepatocellular damage and therapeutic response in chronic hepatitis C, Braz J Infect Dis, 13, 375, 10.1590/S1413-86702009000500013 Zdanov, 2004, Structural features of the interleukin-10 family of cytokines, Curr Pharm Des, 10, 3873, 10.2174/1381612043382602 Moore, 2001, Interleukin-10 and the interleukin-10 receptor, Annu Rev Immunol, 19, 683, 10.1146/annurev.immunol.19.1.683 Asadullah, 2003, Interleukin-10 therapy-review of a new approach, Pharmacol Rev, 55, 241, 10.1124/pr.55.2.4 Boyer, 2000, Pathogenesis, diagnosis and management of hepatitis C, J Hepatol, 32, 98, 10.1016/S0168-8278(00)80419-5 Pestka, 2004, Interleukin-10 and related cytokines and receptors, Annu Rev Immunol, 22, 929, 10.1146/annurev.immunol.22.012703.104622 Bruno, 2011, Relationship between circulating interleukin-10 and histological features in patients with chronic C hepatitis, Ann Saudi Med, 31, 360, 10.4103/0256-4947.83215 Kamal, 2003, Serum and intrahepatic cytokine patterns in hepatitis B and C, Egypt J Med Lab Sci (ESIC), 12 Song le, 2003, Serum cytokine profiles associated with clinical presentation in Vietnamese infected with hepatitis B virus, J Clin Virol, 28, 93, 10.1016/S1386-6532(02)00271-8 Gao, 2009, Polymorphisms of some cytokines and chronic hepatitis B and C virus infection, World J Gastroenterol, 15, 5610, 10.3748/wjg.15.5610 Karim, 2007, Serum Interleukin-10 level in patients with chronic hepatitis B infection, Hungar Med J, 1, 241, 10.1556/HMJ.1.2007.2.11 McCaughan, 2004, Fibrosis progression in chronic hepatitis C virus infection, Gut, 53, 318, 10.1136/gut.2003.026393 Abayli, 2003, Serum profile of T helper 1 and T helper 2 cytokines in patients with chronic hepatitis C virus infection, Turk J Gastroenterol, 14, 7 Sofian, 2012, Serum profile of T helper 1 and T helper 2 cytokines in hepatitis C virus infected patients, Hepat Mon, 12, 6156, 10.5812/hepatmon.6156 Malek, 2010, Interleukin-2 receptor signaling: at the interface between tolerance and immunity, Immunity, 33, 153, 10.1016/j.immuni.2010.08.004 Bachmann, 2007, Interleukin 2: from immunostimulation to immunoregulation and back again, EMBO Rep, 8, 1142, 10.1038/sj.embor.7401099 Xiao, 2006, Serum soluble interleukin-2 receptor levels in patients with chronic hepatitis B virus infection and its relation with anti-HBc, World J Gastroenterol, 12, 482, 10.3748/wjg.v12.i3.482 Spanakis, 2002, Cytokine serum levels in patients with chronic HCV infection, J Clin Lab Anal, 16, 40, 10.1002/jcla.2060 Gramenzi, 2005, Cytokine profile of peripheral blood mononuclear cells from patients with different outcomes of hepatitis C virus infection, J Viral Hepat, 12, 525, 10.1111/j.1365-2893.2005.00634.x Persico, 2000, Natural history of hepatitis C virus carriers with persistently normal aminotransferase levels, Gastroenterology, 118, 760, 10.1016/S0016-5085(00)70145-4 Zamorano, 2003, Interleukin-4: a multifunctional cytokine, Inmunología, 22, 215 Aoudjehane, 2007, Interleukin-4 induces human hepatocyte apoptosis through a Fas-independent pathway, FASEB J, 12, 1433, 10.1096/fj.06-6319com Lin, 2003, IL-4 suppresses the expression and the replication of hepatitis B virus in the hepatocellular carcinoma cell line Hep3B, J Immunol, 171, 4708, 10.4049/jimmunol.171.9.4708 Gigi, 2008, Cytokine mRNA expression in hepatitis C virus infection: TH1 predominance in patients with chronic hepatitis C and TH1-TH2 cytokine profile in subjects with self-limited disease, J Viral Hepat, 15, 145 Nejatollahi, 2011, Interferon-gamma, Interleukin-10 and interleukin-4 in the blood sera of patients with chronic hepatitis B virus infection in Shiraz Reuter, 2009, Tumor necrosis factor a induces g-glutamyltransferase expression via nuclear factor-kB in cooperation with Sp1, Biochem Pharmacol, 77, 397, 10.1016/j.bcp.2008.09.041 Ding, 2006, Alterations of biliary biochemical constituents and cytokines in infantile hepatitis syndrome, World J Gastroenterol, 12, 7038, 10.3748/wjg.v12.i43.7038 Farghaly, 2007, Impact of serum interleukin-10 in pathogenesis of chronicity in hepatitis C virus patients, Egypt J Med Microbiol, 16, 301