Evaluation of phenylmethanesulfonyl fluoride (PMSF) as a tracer candidate mapping acetylcholinesterase in vivo

Nuclear Medicine and Biology - Tập 20 - Trang 991-992 - 1993
Toshiaki Irie1, Kiyoshi Fukushi1, Masaomi Iyo1
1Division of Clinical Research, National Institute of Radiological Sciences, Chiba 263, Japan

Tài liệu tham khảo

Bonnot-Lours, 1992, Synthesis of [11C]methylisocyanate. Application to the labelling of a potent acetylcholinesterase inhibitor: [11C]physostigmine, 152 Ellman, 1961, A new and rapid colorimetric determination of acetylcholinesterase activity, Biochem. Pharmacol., 7, 88, 10.1016/0006-2952(61)90145-9 Fahrney, 1963, Sulfonyl fluorides as inhibitors of esterases. I. Rates of reaction with acetyl-cholinesterase, chymotrypsin, and trypsin, J. Am. Chem. Soc., 85, 997, 10.1021/ja00890a037 Glowinski, 1966, Regional studies of catecholamines in the rat brain—I, J. Neurochem., 13, 655, 10.1111/j.1471-4159.1966.tb09873.x Kitz, 1962, Esters of methanesulfonic acid as irreversible inhibitors of acetylcholinesterase, J. Biol. Chem., 237, 3245, 10.1016/S0021-9258(18)50153-8 Lear, 1982, Evaluation of [123I]isopropyliodoamphetamine as a tracer for local cerebral blood flow using direct autoradiographic comparison, J. Cereb. Bld Flow Metab., 21, 179, 10.1038/jcbfm.1982.17 Moss, 1985, The sulfonyl fluorides: CNS-selective cholinesterase inhibitors with potential value in Alzheimer's disease?, 337 Myers, 1954, Inhibition of esterases by the fluorides of organic acids, Nature, 173, 32, 10.1038/173033a0 Prenant, 1990, Synthesis of [11C]-sarin, J. Labelled Cmpd. Radiopharm., 28, 655, 10.1002/jlcr.2580280604 Whitehouse, 1982, Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain, Science, 215, 1237, 10.1126/science.7058341