Evaluation of macular and peripapillary vessel flow density in eyes with no known pathology using optical coherence tomography angiography

Muhammad Hassan1, Mohammad Ali Sadiq1, Muhammad Sohail Halim1, Rubbia Afridi1, Mohamed Kamel Soliman2, Salman Sarwar2, Aniruddha Agarwal3, V. Diana2, Quan Dong Nguyen2, Yasir J. Sepah2
1Department of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, CA, 94303, USA
2Ocular Imaging Research and Reading Center, Menlo Park, CA, USA
3Post Graduate Institute of Medical Education and Research, Chandigarh, India

Tóm tắt

Từ khóa


Tài liệu tham khảo

Yu DY, Cringle SJ. Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal disease. Prog Retin Eye Res. 2001;20:175–208.

Yu DY, Cringle SJ, Su EN. Intraretinal oxygen distribution in the monkey retina and the response to systemic hyperoxia. Invest Ophthalmol Vis Sci. 2005;46:4728–33.

Snodderly DM, Weinhaus RS, Choi JC. Neural-vascular relationships in central retina of macaque monkeys (Macaca fascicularis). J Neurosci. 1992;12:1169–93.

Chan G, Balaratnasingam C, Yu PK, Morgan WH, McAllister IL, Cringle SJ, Yu DY. Quantitative morphometry of perifoveal capillary networks in the human retina. Invest Ophthalmol Vis Sci. 2012;53:5502–14.

Pournaras CJ, Rungger-Brandle E, Riva CE, Hardarson SH, Stefansson E. Regulation of retinal blood flow in health and disease. Prog Retin Eye Res. 2008;27:284–330.

Tick S, Rossant F, Ghorbel I, Gaudric A, Sahel JA, Chaumet-Riffaud P, Paques M. Foveal shape and structure in a normal population. Invest Ophthalmol Vis Sci. 2011;52:5105–10.

Marmor MF, Ravin JG. Fluorescein angiography: insight and serendipity a half century ago. Arch Ophthalmol. 2011;129:943–8.

Savastano MC, Lumbroso B, Rispoli M. In vivo characterization of retinal vascularization morphology using optical coherence tomography angiography. Retina. 2015;35:2196–203.

Jia Y, Tan O, Tokayer J, Potsaid B, Wang Y, Liu JJ, Kraus MF, Subhash H, Fujimoto JG, Hornegger J, Huang D. Split-spectrum amplitude-decorrelation angiography with optical coherence tomography. Opt Express. 2012;20:4710–25.

Rispoli M, Savastano MC, Lumbroso B. Capillary network anomalies in branch retinal vein occlusion on optical coherence tomography angiography. Retina. 2015;35:2332–8.

Kuehlewein L, Dansingani KK, de Carlo TE, Bonini Filho MA, Iafe NA, Lenis TL, Freund KB, Waheed NK, Duker JS, Sadda SR, Sarraf D. Optical coherence tomography angiography of type 3 neovascularization secondary to age-related macular degeneration. Retina. 2015;35:2229–35.

Agemy SA, Scripsema NK, Shah CM, Chui T, Garcia PM, Lee JG, Gentile RC, Hsiao YS, Zhou Q, Ko T, Rosen RB. Retinal vascular perfusion density mapping using optical coherence tomography angiography in normals and diabetic retinopathy patients. Retina. 2015;35:2353–63.

Miwa Y, Murakami T, Suzuma K, Uji A, Yoshitake S, Fujimoto M, Yoshitake T, Tamura Y, Yoshimura N. Relationship between functional and structural changes in diabetic vessels in optical coherence tomography angiography. Sci Rep. 2016;6:29064.

Cheng L, Chen X, Weng S, Mao L, Gong Y, Yu S, Xu X. Spectral-domain optical coherence tomography angiography findings in multifocal choroiditis with active lesions. Am J Ophthalmol. 2016;169:145–61.

Gadde SG, Anegondi N, Bhanushali D, Chidambara L, Yadav NK, Khurana A, Sinha Roy A. Quantification of vessel density in retinal optical coherence tomography angiography images using local fractal dimension. Invest Ophthalmol Vis Sci. 2016;57:246–52.

Shahlaee A, Samara WA, Hsu J, Say EA, Khan MA, Sridhar J, Hong BK, Shields CL, Ho AC. In vivo assessment of macular vascular density in healthy human eyes using optical coherence tomography angiography. Am J Ophthalmol. 2016;165:39–46.

Kuehlewein L, Tepelus TC, An L, Durbin MK, Srinivas S, Sadda SR. Noninvasive visualization and analysis of the human parafoveal capillary network using swept source OCT optical microangiography. Invest Ophthalmol Vis Sci. 2015;56:3984–8.

Chakravarthy U, Gardiner TA. Endothelium-derived agents in pericyte function/dysfunction. Prog Retin Eye Res. 1999;18:511–27.

Wang X, Kong X, Jiang C, Li M, Yu J, Sun X. Is the peripapillary retinal perfusion related to myopia in healthy eyes? A prospective comparative study. BMJ Open. 2016;6:e010791.

Liu X, Shen M, Yuan Y, Huang S, Zhu D, Ma Q, Ye X, Lu F. Macular thickness profiles of intraretinal layers in myopia evaluated by ultrahigh-resolution optical coherence tomography. Am J Ophthalmol. 2015;160(53–61):e52.

Samara WA, Say EA, Khoo CT, Higgins TP, Magrath G, Ferenczy S, Shields CL. Correlation of foveal avascular zone size with foveal morphology in normal eyes using optical coherence tomography angiography. Retina. 2015;35:2188–95.

Liu L, Jia Y, Takusagawa HL, Pechauer AD, Edmunds B, Lombardi L, Davis E, Morrison JC, Huang D. Optical coherence tomography angiography of the peripapillary retina in glaucoma. JAMA Ophthalmol. 2015;133:1045–52.

Hollo G. Vessel density calculated from OCT angiography in 3 peripapillary sectors in normal, ocular hypertensive, and glaucoma eyes. Eur J Ophthalmol. 2016;26:e42–5.