Evaluation of a pediatric liquid formulation to improve 6-mercaptopurine therapy in children

European Journal of Pharmaceutical Sciences - Tập 83 - Trang 1-7 - 2016
Adam de Beaumais Tiphaine1, Lisa Lynqsie Hjalgrim2, Jacob Nersting2, Joerg Breitkreutz3, Brigitte Nelken4, Martin Schrappe5, Martin Stanulla6, Caroline Thomas7, Yves Bertrand8, Guy Leverger9, André Baruchel10,11, Kjeld Schmiegelow2,12, Evelyne Jacqz-Aigrain1,11
1Department of Pediatric Pharmacology and Pharmacogenetics and Clinical Investigations Center CIC1426 INSERM, Robert Debre Hospital, Assistance Publique Hopitaux de Paris, Paris, France
2Department of Pediatrics and Adolescent Medicine, University Hospital, Copenhagen, Denmark
3Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine-University, Universitätsstrasse 1, Düsseldorf, Germany
4Department of Paediatric Haematology/Oncology, University Hospital of Jeanne de Flandre, Lille, France
5University Medical Center Schleswig-Holstein, Campus Kiel Schwanenweg, Kiel, Germany
6Medical Scholl Hannover, Department of Pediatric Hematology and Oncology, Hannover, Germany
7Immunohematology and Pediatric Oncology Department, Mother Child Hospital, Nantes, France
8Institute of Haematology and Paediatric Oncology, Hospices Civils de Lyon, Lyon, France
9UPMC University Paris 06, Paediatric Haematology Oncology Unit, Armand Trousseau Hospital, Assistance Publique Hopitaux de Paris, Paris, France
10Paediatric Immunology and Haematology Department, Robert Debre Hospital, Assistance Publique Hopitaux de Paris, Paris, France
11University Paris VII Diderot, Paris, France
12Institute of Clinical Medicine, University of Copenhagen, Denmark

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