Evaluating tear clearance rate with optical coherence tomography

Tomlinson, 2005, Assessment of tear film dynamics: quantification approach, Ocul. Surf., 3, 81, 10.1016/S1542-0124(12)70157-X de Paiva, 2004, Tear clearance implications for ocular surface health, Exp. Eye Res., 78, 395, 10.1016/j.exer.2003.08.003 Nelson, 1995, Simultaneous evaluation of tear turnover and corneal epithelial permeability by fluorophotometry in normal subjects and patients with keratoconjunctivitis sicca (KCS), Trans. Am. Ophthalmol. Soc., 93, 709 Pflugfelder, 1998, Evaluation of subjective assessments and objective diagnostic tests for diagnosing tear-film disorders known to cause ocular irritation, Cornea, 17, 38, 10.1097/00003226-199801000-00007 Prabhasawat, 1998, Frequent association of delayed tear clearance in ocular irritation, Br. J. Ophthalmol., 82, 666, 10.1136/bjo.82.6.666 Afonso, 1999, Correlation of tear fluorescein clearance and Schirmer test scores with ocular irritation symptoms, Ophthalmology, 106, 803, 10.1016/S0161-6420(99)90170-7 Macri, 2000, Correlation of the Schirmer 1 and fluorescein clearance tests with the severity of corneal epithelial and eyelid disease, Arch. Ophthalmol., 118, 1632, 10.1001/archopht.118.12.1632 Pflugfelder, 2017, 739 Afonso, 1999, Tear fluid gelatinase B activity correlates with IL-1α concentration and fluorescein clearance in ocular rosacea, Invest. Ophthalmol. Vis. Sci., 40, 2506 Macri, 2000, A standardized visual scale for evaluation of tear fluorescein clearance, Ophthalmology, 107, 1338, 10.1016/S0161-6420(00)00101-9 Dursun, 2002, A mouse model of keratoconjunctivitis sicca, Invest. Ophthalmol. Vis. Sci., 43, 632 Jordan, 1980, Basic tear flow: does it exist?, Ophthalmology, 87, 920, 10.1016/S0161-6420(80)35143-9 Sorbara, 2004, Tear turnover rate is reduced in patients with symptomatic dry eye, Cont. Lens Anterior Eye, 27, 15, 10.1016/j.clae.2003.10.001 Göbbels, 1991, Tear secretion in dry eyes as assessed by objective fluorophotometry, Ger. J. Ophthalmol., 1, 350 Mathers, 1996, Model for ocular tear film function, Cornea, 15, 110, 10.1097/00003226-199603000-00002 Chang, 2001, Delayed tear clearance in contact lens associated papillary conjunctivitis, Curr. Eye Res., 22, 253, 10.1076/ceyr.22.4.253.5504 Kuppens, 1992, Basal tear turnover and topical timolol in glaucoma patients and healthy controls by fluorophotometry, Invest. Ophthalmol. Vis. Sci., 33, 3442 van Best, 1995, Measurement of basal tear turnover using a standardized protocol, Graefe's Arch. Clin. Exp. Ophthalmol., 233, 1, 10.1007/BF00177778 Webber, 1986, Continuous fluorophotometric method of measuring tear turnover rate in humans and analysis of factors affecting accuracy, Med. Biol. Eng. Comput., 24, 386, 10.1007/BF02442693 Xu, 1995, Correlation of tear clearance rate and fluorophotometric assessment of tear turnover, Br. J. Ophthalmol., 79, 1042, 10.1136/bjo.79.11.1042 Webber, 1987, Fluorophotometric measurements of tear turnover rate in normal healthy persons: evidence for a circadian rhythm, Eye, 1, 615, 10.1038/eye.1987.95 Best, 1983, Computer fluorophotometry, Doc. Ophthalmol., 56, 89, 10.1007/BF00154714 Occhipinti, 1988, Fluorophotometric measurement of human tear turnover rate, Curr. Eye Res., 7, 995, 10.3109/02713688809015145 Pearce, 2001, An improved fluorophotometric method for tear turnover assessment, Optom. Vis. Sci., 78, 30, 10.1097/00006324-200101010-00011 Joshi, 1996, A new method for determining corneal epithelial barrier to fluorescein in humans, Invest. Ophthalmol. Vis. Sci., 37, 1008 Benedetto, 1984, In vivo observation of tear dynamics using fluorophotometry, Arch. Ophthalmol., 102, 410, 10.1001/archopht.1984.01040030328030 Mishima, 1966, Determination of tear volume and tear flow, Invest. Ophthalmol. Vis. Sci., 5, 264 Hurwitz, 1975, Quantitative lacrimal scintillography. I. Method and physiological application, Br. J. Ophthalmol., 59, 308, 10.1136/bjo.59.6.308 Chavis, 1978, Quantitative lacrimal scintillography, Arch. Ophthalmol., 96, 2066, 10.1001/archopht.1978.03910060454013 Hilditch, 1983, Lacrimal scintigraphy. I. Compartmental analysis of data, Br. J. Ophthalmol., 67, 713, 10.1136/bjo.67.11.713 Rossomondo, 1972, A new method of evaluating lacrimal drainage, Arch. Ophthalmol., 88, 523, 10.1001/archopht.1972.01000030525010 Maurice, 1992, Use of fluorometry in assessing the efficacy of a cation-sensitive gel as an ophthalmic vehicle: comparison with scintigraphy, J. Pharm. Sci., 81, 615, 10.1002/jps.2600810704 Puffer, 1980, Basal precorneal tear turnover in the human eye, Am. J. Ophthalmol., 89, 369, 10.1016/0002-9394(80)90006-9 Bron, 2007, Methodologies to diagnose and monitor dry eye disease: report of the Diagnostic Methodology Subcommittee of the International Dry Eye WorkShop (2007), Ocul. Surf., 5, 108, 10.1016/S1542-0124(12)70083-6 Zheng, 2014, New method for evaluation of early phase tear clearance by anterior segment optical coherence tomography, Acta Ophthalmol. (Copenh.), 92, e105, 10.1111/aos.12260 Shen, 2009, Upper and lower tear menisci in the diagnosis of dry eye, Invest. Ophthalmol. Vis. Sci., 50, 2722, 10.1167/iovs.08-2704 Czajkowski, 2012, Tear meniscus measurement by spectral optical coherence tomography, Optom. Vis. Sci., 89, 336, 10.1097/OPX.0b013e318242042b Chen, 2009, Lower volumes of tear menisci in contact lens wearers with dry eye symptoms, Invest. Ophthalmol. Vis. Sci., 50, 3159, 10.1167/iovs.08-2794 Chen, 2010, Ultrahigh-resolution measurement by optical coherence tomography of dynamic tear film changes on contact lenses, Invest. Ophthalmol. Vis. Sci., 51, 1988, 10.1167/iovs.09-4389 Wang, 2008, Dynamic distribution of artificial tears on the ocular surface, Arch. Ophthalmol., 126, 619, 10.1001/archopht.126.5.619 Wang, 2006, Repeated measurements of dynamic tear distribution on the ocular surface after instillation of artificial tears, Invest. Ophthalmol. Vis. Sci., 47, 3325, 10.1167/iovs.06-0055 Bartuzel, 2014, Automatic dynamic tear meniscus measurement in optical coherence tomography, Biomed. Opt. Express, 5, 2759, 10.1364/BOE.5.002759 Zheng, 2016, Visualization of tear clearance using anterior segment optical coherence tomography and polymethylmethacrylate particles, Cornea, 35, S78, 10.1097/ICO.0000000000000997 White, 1991, Effect of blinking on tear elimination as evaluated by dacryoscintigraphy, Ophthalmology, 98, 367, 10.1016/S0161-6420(91)32287-5 Patton, 1975, Influence of topical anesthesia on tear dynamics and ocular drug bioavailability in albino rabbits, J. Pharm. Sci., 64, 267, 10.1002/jps.2600640215 Johnson, 2006, Temporal changes in the tear menisci following a blink, Exp. Eye Res., 83, 517, 10.1016/j.exer.2006.02.002 Wu, 2015, The effects of increasing ocular surface stimulation on blinking and tear SecretionOcular stimulation effects on blinking and tear secretion, Invest. Ophthalmol. Vis. Sci., 56, 4211, 10.1167/iovs.14-16313 Sullivan, 2012, Clinical utility of objective tests for dry eye disease: variability over time and implications for clinical trials and disease management, Cornea, 31, 1000, 10.1097/ICO.0b013e318242fd60 Garcia-Lázaro, 2011, Comparison of two artificial tear formulations for dry eye through high-resolution optical coherence tomography, Clin. Exp. Optom., 94, 549, 10.1111/j.1444-0938.2011.00632.x Garcia-Lázaro, 2012, OCT for assessing artificial tears effectiveness in contact lens wearers, Optom. Vis. Sci., 89, E62, 10.1097/OPX.0b013e318237a9d2